Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells

scientific article

Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/MOLEHR/GAV058
P932PMC publication ID4664393
P698PubMed publication ID26502803

P2093author name stringLi Zhou
Yu Zhou
Wen-Zhe Ho
Ming Sang
Jian-Guo Wu
Jie-Liang Li
Shi Liu
Ke Zhuang
Jin-Biao Liu
Jian-Feng Gao
P2860cites workTLR9 and RIG-I signaling in human endocervical epithelial cells modulates inflammatory responses of macrophages and dendritic cells in vitroQ24318849
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The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the glucocorticoid receptorQ33631772
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Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?Q35173777
Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivoQ35803282
Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I AgonistsQ35861232
A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challengeQ35871689
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Induction of interferon-γ contributes to Toll-like receptor 3-mediated herpes simplex virus type 1 inhibition in astrocytesQ36138293
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Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon productionQ36684310
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Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.Q36978882
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Activation of toll-like receptor-3 induces interferon-lambda expression in human neuronal cellsQ37116204
Herpes simplex virus 1-encoded tegument protein VP16 abrogates the production of beta interferon (IFN) by inhibiting NF-κB activation and blocking IFN regulatory factor 3 to recruit its coactivator CBP.Q37123477
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Activation of Toll-like receptors inhibits herpes simplex virus-1 infection of human neuronal cellsQ37603985
Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa.Q37844936
CpG DNA stimulates autoreactive immature B cells in the bone marrowQ38302173
RIG-I from waterfowl and mammals differ in their abilities to induce antiviral responses against influenza A virusesQ38942594
Herpes simplex virus type 2 virion host shutoff protein suppresses innate dsRNA antiviral pathways in human vaginal epithelial cellsQ39532187
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Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA.Q40501018
Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cellsQ40545654
The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/betaQ40745643
Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signalingQ40748984
Proteomic analysis of the occlusion-derived virus of Clostera anachoreta granulovirusQ41074763
Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteinsQ41088834
Development of a novel thermostable Newcastle disease virus vaccine vector for expression of a heterologous gene.Q41518884
Interferon lambda 1 expression in cervical cells differs between low-risk and high-risk human papillomavirus-positive women.Q42238119
Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2.Q42453950
The complete mitochondrial genome sequence of Metzia formosae (Cypriniformes, Cyprinidae).Q42617495
Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women.Q45388640
An international, randomized, double-blind, placebo-controlled, study of valacyclovir for the suppression of herpes simplex virus type 2 genital herpes in newly diagnosed patientsQ45395249
Herpes simplex virus 2 virion host shutoff protein interferes with type I interferon production and responsivenessQ45656675
P433issue12
P921main subjecttoll-like receptorQ408004
P304page(s)917-929
P577publication date2015-10-26
P1433published inMolecular Human ReproductionQ15761794
P1476titleInduction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells
P478volume21

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cites work (P2860)
Q57473488Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells
Q37571601Functional Roles of Pattern Recognition Receptors That Recognize Virus Nucleic Acids in Human Adipose-Derived Mesenchymal Stem Cells.
Q90386579Human Cervical Epithelial Cells Release Antiviral Factors and Inhibit HIV Replication in Macrophages
Q53681760IFN-λs inhibit Hantaan virus infection through the JAK-STAT pathway and expression of Mx2 protein.
Q47141979Interferon Lambda Genetics and Biology in Regulation of Viral Control
Q37670446Interferon Lambda: Modulating Immunity in Infectious Diseases
Q33439601Severe fever with thrombocytopenia syndrome virus inhibits exogenous Type I IFN signaling pathway through its NSs invitro
Q40076047The Us2 Gene Product of Herpes Simplex Virus 2 modulates NF-κB activation by targeting TAK1.

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