Cloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin

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Cloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M306724200
P8608Fatcat IDrelease_52c4cv6wkvdxpfnbghfinlegeq
P698PubMed publication ID14525992

P50authorSandor BenyheQ44343306
P2093author name stringAlina-Elena Ilie
Anna Borsodi
Geza Toth
Patrick Pattee
Srinivasa R Nagalla
P2860cites workIsolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptorQ24311708
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Cloning of a delta opioid receptor by functional expressionQ28213132
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterizationQ30800519
cDNAs encoding [D-Ala2]deltorphin precursors from skin of Phyllomedusa bicolor also contain genetic information for three dermorphin-related opioid peptidesQ33646931
Identification of two related pentapeptides from the brain with potent opiate agonist activityQ34134593
Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursorQ34634402
Cloning and sequence analysis of cDNA for porcine β-neo-endorphin/dynorphin precursorQ34707265
Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalinQ34708228
Endogenous opioid peptides: multiple agonists and receptorsQ34986433
A dynorphin-like opioid in the central nervous system of an amphibianQ36297189
Porcine pituitary dynorphin: complete amino acid sequence of the biologically active heptadecapeptideQ36380726
D-alanine in the frog skin peptide dermorphin is derived from L-alanine in the precursorQ36471715
Dermorphin-related peptides from the skin of Phyllomedusa bicolor and their amidated analogs activate two mu opioid receptor subtypes that modulate antinociception and catalepsy in the ratQ37140069
Evidence for a proenkephalin-like precursor in amphibian brainQ37349862
There are three distinct forms of bombesin. Identification of [Leu13]bombesin, [Phe13]bombesin, and [Ser3,Arg10,Phe13]bombesin in the frog Bombina orientalisQ38360022
Endogenous opiates: 1992.Q40728306
Characterization of mu, kappa, and delta opioid binding in amphibian whole brain tissue homogenatesQ43926227
Kinetics and physical parameters of rat brain opioid receptors solubilized by digitonin and CHAPS.Q44346633
Solubilization and characterization of opioid binding sites from frog (Rana esculenta) brainQ44351469
Dynorphin Is a Specific Endogenous Ligand of the κ Opioid ReceptorQ44352111
Biosynthetic origin and receptor conformation of methionine enkephalinQ44925269
Polymorphism and absence of Leu-enkephalin sequences in proenkephalin genes in Xenopus laevisQ46921272
Binding characteristics of the novel highly selective delta agonist, [3H]IIe5,6deltorphin II.Q48149022
Opioids and testicular activity in the frog, Rana esculentaQ48307797
Opiate agonists and antagonists discriminated by receptor binding in brainQ48611095
Distribution of proenkephalin-derived peptides in the brain of Rana esculentaQ69736646
Immunohistochemistry and nerve lesion experiments on the methionine-enkephalin immunopositive neurons in the small intestine of the bullfrog (Rana catesbeiana)Q70586712
P433issue52
P407language of work or nameEnglishQ1860
P921main subjectopioidQ427523
African clawed frogQ654718
P1104number of pages7
P304page(s)53098-53104
P577publication date2003-10-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleCloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin
P478volume278

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cites work (P2860)
Q36576077Are lungfish living fossils? Observation on the evolution of the opioid/orphanin gene family
Q28752305Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates
Q37851161Evolution of POMC: origin, phylogeny, posttranslational processing, and the melanocortins
Q83159353Evolution of gnathostome prodynorphin and proenkephalin: characterization of a shark proenkephalin and prodynorphin cDNAs
Q37799407Observations on the radiation of lobe-finned fishes, ray-finned fishes, and cartilaginous fishes: Phylogeny of the opioid/orphanin gene family and the 2R hypothesis
Q35007416Pathobiology of dynorphins in trauma and disease
Q27318592Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides
Q36125419Trends in the evolution of the proenkephalin and prodynorphin genes in gnathostomes
Q33273166Xendorphin B1, a novel opioid-like peptide determined from a Xenopus laevis brain cDNA library, produces opioid antinociception after spinal administration in amphibians

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