Advances in high-field magnetic resonance spectroscopy in Alzheimer's disease

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Advances in high-field magnetic resonance spectroscopy in Alzheimer's disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.2174/1567205011666140302200312
P932PMC publication ID4108086
P698PubMed publication ID24597505
P5875ResearchGate publication ID260561310

P50authorKenneth RockwoodQ57982861
P2093author name stringXiaowei Song
Robert Bartha
Ningnannan Zhang
Yunting Zhang
Steven Beyea
Ryan D'Arcy
P2860cites work1 H MR Spectroscopy of the Brain: Absolute Quantification of Metabolites 1Q22065378
Alzheimer's DiseaseQ22248111
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseQ24595802
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseQ29547554
Increased glucose concentration in the hippocampus in early Alzheimer's disease following oral glucose ingestionQ30440916
In vivo 1H NMR spectroscopy of the human brain at 9.4 T: initial resultsQ30474364
Proton MRS in mild cognitive impairmentQ30606675
Magnetic resonance spectroscopy in Alzheimer's diseaseQ30630699
Role of Increased Cerebral myo‐Inositol in the Dementia of Down SyndromeQ45307554
An MRI brain atrophy and lesion index to assess the progression of structural changes in Alzheimer's disease, mild cognitive impairment, and normal aging: a follow-up study.Q45715352
Comparison of machine learning techniques with classical statistical models in predicting health outcomes.Q45966672
A multicenter (1)H-MRS study of the medial temporal lobe in AD and MCI.Q46006742
Conversion to dementia in mild cognitive impairment is associated with decline of N-actylaspartate and creatine as revealed by magnetic resonance spectroscopy.Q46019129
Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopyQ46412580
Absolute quantification in proton magnetic resonance spectroscopy is superior to relative ratio to discriminate Alzheimer's disease from Binswanger's diseaseQ46490260
Conversion of MCI to dementia: Role of proton magnetic resonance spectroscopyQ46528864
Choline ingestion increases the resonance of choline-containing compounds in human brain: an in vivo proton magnetic resonance studyQ42278805
Combining MRI and MRS to distinguish between Alzheimer's disease and healthy controlsQ42905311
Absolute Quantification in Proton Magnetic Resonance Spectroscopy Is Useful to Differentiate Amnesic Mild Cognitive Impairment from Alzheimer’s Disease and Healthy AgingQ42944825
Memantine versus donepezil in mild to moderate Alzheimer's disease: a randomized trial with magnetic resonance spectroscopyQ43252674
Increased glutamate in the hippocampus after galantamine treatment for Alzheimer diseaseQ43260715
Dynamics of brain structure and cognitive function in the Alzheimer's disease neuroimaging initiativeQ43683015
In vivo 1H NMR spectroscopy of the human brain at 7 T.Q43732942
Biexponential transverse relaxation (T(2)) of the proton MRS creatine resonance in human brainQ43866051
Proton MR spectroscopic study at 3 Tesla on glutamate/glutamine in Alzheimer's diseaseQ43941006
Longitudinal quantitative proton magnetic resonance spectroscopy of the hippocampus in Alzheimer's diseaseQ44147111
Impaired visual recognition memory in amnestic mild cognitive impairment is associated with mesiotemporal metabolic changes on magnetic resonance spectroscopic imagingQ44266860
Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3 TQ44441773
Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopyQ44643487
A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brainQ44878088
Regional metabolic changes in the hippocampus and posterior cingulate area detected with 3-Tesla magnetic resonance spectroscopy in patients with mild cognitive impairment and Alzheimer diseaseQ44940013
High cerebral scyllo-inositol: a new marker of brain metabolism disturbances induced by chronic alcoholismQ45039345
Proton spectroscopy in Alzheimer's disease and cognitive impairment no dementia: a community-based studyQ46622896
High field (1)H MRS of the hippocampus after donepezil treatment in Alzheimer disease.Q46770368
Focally elevated creatine detected in amyloid precursor protein (APP) transgenic mice and Alzheimer disease brain tissueQ46788465
Validation of glutathione quantitation from STEAM spectra against edited 1H NMR spectroscopy at 4T: application to schizophreniaQ46829361
Proton MRS of the unilateral substantia nigra in the human brain at 4 tesla: detection of high GABA concentrations.Q46891214
Magnetic resonance spectroscopic study of Alzheimer's disease and frontotemporal dementia/Pick complex.Q46973579
A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's diseaseQ47401613
A localized double-quantum filter for in vivo detection of taurineQ48124229
Factors affecting the quantification of short echo in-vivo 1H MR spectra: prior knowledge, peak elimination, and filteringQ48152149
Identification of Scyllo-inositol in proton NMR spectra of human brain in vivo.Q48368950
Spectral editing technique for the in vitro and in vivo detection of taurineQ48434937
Robust fully automated shimming of the human brain for high-field 1H spectroscopic imagingQ48500479
On areas of transition between entorhinal allocortex and temporal isocortex in the human brain. Normal morphology and lamina-specific pathology in Alzheimer's diseaseQ48538921
Changes of hippocampal N-acetyl aspartate and volume in Alzheimer's disease. A proton MR spectroscopic imaging and MRI studyQ48577021
Hippocampal metabolites and memory performances in patients with amnestic mild cognitive impairment and Alzheimer's diseaseQ48628708
Longitudinal magnetic resonance spectroscopy as marker of cognitive deterioration in mild cognitive impairmentQ48665796
The return of the frequency sweep: designing adiabatic pulses for contemporary NMR.Q48691421
Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS.Q48732771
On the identification of cerebral metabolites in localized1H NMR spectra of human brainIn vivoQ48763413
Automatic quantitation of localized in vivo 1H spectra with LCModelQ48842365
Single-voxel proton MRS of the human brain at 1.5T and 3.0T.Q48899796
Improved quantification of in vivo 1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fittingQ48930170
Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementiasQ49039021
Quantitative proton MR spectroscopic imaging of the human brainQ49094238
Evaluation of common structural brain changes in aging and Alzheimer disease with the use of an MRI-based brain atrophy and lesion index: a comparison between T1WI and T2WI at 1.5T and 3T.Q49100694
Using proton magnetic resonance spectroscopy to identify mild cognitive impairmentQ49162235
Longitudinal study of amnesic patients at high risk for Alzheimer's disease: clinical, neuropsychological and magnetic resonance spectroscopy features.Q51108602
Brain oxidative stress: detection and mapping of anti-oxidant marker 'Glutathione' in different brain regions of healthy male/female, MCI and Alzheimer patients using non-invasive magnetic resonance spectroscopy.Q51173688
Executive function is associated with brain proton magnetic resonance spectroscopy in amnestic mild cognitive impairment.Q51972858
Similar 1H magnetic resonance spectroscopic metabolic pattern in the medial temporal lobes of patients with mild cognitive impairment and Alzheimer disease.Q52001947
Morphological changes in the human cerebral cortex in dementiaQ53182084
Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.Q53234286
Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease.Q53236578
1-H MRS changes in dorsolateral prefrontal cortex after donepezil treatment in patients with mild to moderate Alzheimer's disease.Q53319688
Utility of different MR modalities in mild cognitive impairment and its use as a predictor of conversion to probable dementia.Q53394958
1H NMR chemical shift selective (CHESS) imagingQ57530731
Comparison of the quantification precision of human short echo time1H spectroscopy at 1.5 and 4.0 TeslaQ63894296
Measurement of the magnetic susceptibility effect in high-field NMR imagingQ68335776
Estimation of metabolite concentrations from localized in vivo proton NMR spectraQ72319396
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standardQ80406112
Neurochemical alterations of the entorhinal cortex in amnestic mild cognitive impairment (aMCI): a three-year follow-up studyQ84141182
Magnetic resonance spectroscopy in AD.Q30640894
Magnetic resonance spectroscopy in common dementiasQ30660402
High-field magnetic resonance techniques for brain researchQ30884505
High-field proton MRS of human brainQ30886341
Proton magnetic resonance spectroscopy: clinical applications in patients with brain lesionsQ30909042
1H-MRS evaluation of metabolism in Alzheimer's disease and vascular dementia.Q30945792
A review of 1H MR spectroscopy findings in Alzheimer's diseaseQ31030920
A review of chemical issues in 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and cholineQ31033036
N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brainQ31034516
Differential aging of the brain: patterns, cognitive correlates and modifiersQ31055402
The clinical value of proton magnetic resonance spectroscopy in adult brain tumours.Q31090249
Alzheimer disease: postmortem neuropathologic correlates of antemortem 1H MR spectroscopy metabolite measurementsQ31159878
Magnetic resonance spectroscopy of neurotransmitters in human brain.Q33187959
Short echo time 1H-MRSI of the human brain at 3T with minimal chemical shift displacement errors using adiabatic refocusing pulsesQ33304310
Proton magnetic resonance spectroscopy in dementias and mild cognitive impairmentQ33462288
Methodology of H NMR Spectroscopy of the Human Brain at Very High Magnetic FieldsQ33533781
Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRSQ33745448
In vivo 1H NMR spectroscopy of the human brain at high magnetic fields: metabolite quantification at 4T vs. 7T.Q33745500
MR spectroscopy and spectroscopic imaging of the brainQ33807151
Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plansQ33842520
Metabolism and functions of glutathione in brain.Q33908238
Regional neurochemical profiles in the human brain measured by ¹H MRS at 7 T using local B₁ shimming.Q33964122
N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).Q34029600
In vivo detection of serine in the human brain by proton magnetic resonance spectroscopy (1H-MRS) at 7 TeslaQ34067236
7-T MR--from research to clinical applications?Q34079073
Magnetic resonance imaging based clinical research in Alzheimer's diseaseQ34123178
Statin users without an APOE-epsilon4 allele have increased insulin resistanceQ34155597
Short echo time proton magnetic resonance spectroscopy in Alzheimer's disease: a longitudinal multiple time point studyQ34247831
2012 Alzheimer's disease facts and figuresQ34260109
Review: taurine: a "very essential" amino acid.Q34312980
Regional myo-inositol concentration in mild cognitive impairment Using 1H magnetic resonance spectroscopic imagingQ34576451
Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging.Q34652032
Association of 1H-MR spectroscopy and cerebrospinal fluid biomarkers in Alzheimer's disease: diverging behavior at three different brain regionsQ34665673
Reduced hippocampal glutamate in Alzheimer diseaseQ34985347
Noninvasive quantification of ascorbate and glutathione concentration in the elderly human brainQ35056484
Brain metabolic correlates of decision making in amnestic mild cognitive impairmentQ35097548
Magnetic resonance spectroscopy, β-amyloid load, and cognition in a population-based sample of cognitively normal older adultsQ35210272
Magnetic resonance spectroscopy in the prediction of early conversion from amnestic mild cognitive impairment to dementia: a prospective cohort studyQ35319467
Scyllo-inositol in normal aging human brain: 1H magnetic resonance spectroscopy study at 4 TeslaQ35677156
Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imagingQ35677174
The incidence of MCI differs by subtype and is higher in men: the Mayo Clinic Study of AgingQ35758628
Comparison of single-shot localization methods (STEAM and PRESS) for in vivo proton NMR spectroscopyQ35792156
In vivo magnetic resonance spectroscopy of GABA: a methodological reviewQ36060201
Evidence for ordering of Alzheimer disease biomarkersQ36071403
Proton MR spectroscopy-detectable major neurotransmitters of the brain: biology and possible clinical applicationsQ36232627
Combining structural brain changes improves the prediction of Alzheimer's disease and mild cognitive impairmentQ36374662
Spatial localization in NMR spectroscopy in vivoQ36448283
Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxiaQ36626001
Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatmentQ36789901
Clinical applications of proton MR spectroscopyQ36815275
Observation of resolved glucose signals in 1H NMR spectra of the human brain at 4 TeslaQ36818274
Magnetic resonance spectroscopy (MRS) in the evaluation of pediatric brain tumors, Part I: Introduction to MRS.Q36832435
Brain metabolism differs in Alzheimer's disease and Parkinson's disease dementiaQ37010486
Single voxel magnetic resonance spectroscopy at 3 Tesla in a memory disorders clinic: early right hippocampal NAA/Cr loss in mildly impaired subjectsQ37097465
1H magnetic resonance spectroscopy in dementiaQ37150637
MR spectroscopy for assessment of memantine treatment in mild to moderate Alzheimer dementiaQ37150803
Measurement sequences for single voxel proton MR spectroscopy.Q37206676
White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI.Q37319527
Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypesQ37345411
Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS studyQ37407266
Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy studyQ37462401
Neuroimaging results impose new views on Alzheimer's disease--the role of amyloid revisedQ37971458
Longitudinal metabolic and cognitive changes in mild cognitive impairment patientsQ38389274
Metabolite investigation in both anterior and posterior cingulate gyri in Alzheimer's disease spectrum using 3-tesla MR spectroscopyQ38461379
Functional investigation of bilateral posterior cingulate gyri using multivoxel MR spectroscopyQ38463897
Magnetic resonance characterization of ischemic tissue metabolismQ39979430
Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus.Q40028844
Elevated brain scyllo-inositol concentrations in patients with Alzheimer's diseaseQ40243026
Utilization of glutamine and of TCA cycle constituents as precursors for transmitter glutamate and GABA.Q40559826
In vivo spectroscopic quantification of the N-acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: effects of normal agingQ41614051
An Open-Label Exploratory Study with Memantine: Correlation between Proton Magnetic Resonance Spectroscopy and Cognition in Patients with Mild to Moderate Alzheimer's DiseaseQ42103589
P275copyright licenseCreative Commons Attribution 2.5 GenericQ18810333
P433issue4
P921main subjectproton NMRQ1979695
brainQ1073
nervous systemQ9404
Alzheimer's diseaseQ11081
biomedical investigative techniqueQ66648976
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)367-388
P577publication date2014-05-01
P1433published inCurrent Alzheimer ResearchQ5195031
P1476titleAdvances in high-field magnetic resonance spectroscopy in Alzheimer's disease
P478volume11

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cites work (P2860)
Q891220131H MRS spectroscopy in preclinical autosomal dominant Alzheimer disease
Q55031002Acupuncture therapy in treating migraine: results of a magnetic resonance spectroscopy imaging study.
Q30910766Anatomical, functional and molecular biomarker applications of magnetic resonance neuroimaging
Q90049842Brain Amide Proton Transfer Imaging of Rat With Alzheimer's Disease Using Saturation With Frequency Alternating RF Irradiation Method
Q33701135Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images
Q92463658European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)
Q92671500Functional MRI technologies in the study of medication treatment effect on Alzheimer's disease
Q35276630HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease?
Q37430416Human Neural Stem Cell Transplantation Rescues Cognitive Defects in APP/PS1 Model of Alzheimer's Disease by Enhancing Neuronal Connectivity and Metabolic Activity
Q35857773Neurometabolic characteristics in the anterior cingulate gyrus of Alzheimer's disease patients with depression: a (1)H magnetic resonance spectroscopy study
Q36177915Quantitative in vivo neurochemical profiling in humans: where are we now?
Q51761581Royal Jelly Reduces Cholesterol Levels, Ameliorates Aβ Pathology and Enhances Neuronal Metabolic Activities in a Rabbit Model of Alzheimer's Disease.

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