Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data

scientific article

Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/PST.1619
P932PMC publication ID4283755
P698PubMed publication ID24789367
P5875ResearchGate publication ID262026870

P50authorTim FriedeQ58452336
Nigel StallardQ43132046
Nick ParsonsQ53112989
Cornelia U KunzQ55473027
P2093author name stringSusan Todd
P2860cites workCombining multiple comparisons and modeling techniques in dose-response studiesQ81145375
Adaptive designs in clinical drug development--an Executive Summary of the PhRMA Working GroupQ83841990
On closed testing procedures with special reference to ordered analysis of varianceQ29041733
Testing and estimation in flexible group sequential designs with adaptive treatment selectionQ36327917
Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: general conceptsQ36593604
Adaptive designs for confirmatory clinical trialsQ37389417
Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trialQ38483164
A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpointsQ42130183
Adaptive designs for pivotal trials: discussion points from the PSI Adaptive Design Expert Group.Q42602448
An adaptive seamless phase II/III design for oncology trials with subpopulation selection using correlated survival endpointsQ44262116
Interim analysis of continuous long-term endpoints in clinical trials with longitudinal outcomes.Q44446094
A confirmatory seamless phase II/III clinical trial design incorporating short-term endpoint informationQ45374094
Adaptive sample size calculations in group sequential trialsQ47213254
Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosisQ48152166
Time-to-event analysis with treatment arm selection at interim.Q51534010
Evaluation of experiments with adaptive interim analyses.Q52364596
Multiplicity and flexibility in clinical trials.Q53025596
A Multiple Comparison Procedure for Comparing Several Treatments with a ControlQ56838307
Recursive Combination TestsQ57305829
A group-sequential design for clinical trials with treatment selectionQ57430672
P433issue4
P921main subjectphase II clinical trialQ42824440
phase III clinical trialQ42824827
P304page(s)238-246
P577publication date2014-05-02
P1433published inPharmaceutical StatisticsQ7180744
P1476titleData-driven treatment selection for seamless phase II/III trials incorporating early-outcome data
P478volume13

Reverse relations

cites work (P2860)
Q38963322Adaptive graph-based multiple testing procedures
Q41883714Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations.
Q86499109Clinical trials submitted to the JID: place your bet and show us your hand
Q39073427Development of a Bayesian response-adaptive trial design for the Dexamethasone for Excessive Menstruation study
Q34465354Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate: Results of a Phase III Study
Q41857207Type I error rates of multi-arm multi-stage clinical trials: strong control and impact of intermediate outcomes.

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