Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy

scientific article

Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1002595063
P356DOI10.1038/SREP37148
P932PMC publication ID5107909
P698PubMed publication ID27841332

P2093author name stringEiketsu Sho
Zaijun Zhang
Simon M Y Lee
Guohui Li
Ivan K Chu
Pei Yu
Gaoxiao Zhang
Yewei Sun
Yuqiang Wang
Quan Quan
Henry C H Law
Samuel S W Szeto
Michael K W Siu
P2860cites workImproving the efficacy of translational medicine by optimally integrating health care, academia and industryQ82831752
Myelination and the trophic support of long axonsQ83162670
Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical studyQ44300705
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicentersQ44418044
Antioxidative and thrombolytic TMP nitrone for treatment of ischemic strokeQ46368657
Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.Q48158692
Proteomic analysis of mouse brain cortex identifies metabolic down-regulation as a general feature of ischemic pre-conditioningQ48438033
Tetramethylpyrazine Promotes Migration of Neural Precursor Cells via Activating the Phosphatidylinositol 3-Kinase PathwayQ48451254
Vimentin participates in microglia activation and neurotoxicity in cerebral ischemia.Q48479135
A latent neurogenic program in astrocytes regulated by Notch signaling in the mouseQ48491021
Therapeutic effects of tetramethylpyrazine nitrone in rat ischemic stroke modelsQ48606610
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brainQ48629603
Changes in the concentrations of cerebral proteins following occlusion of the middle cerebral artery in ratsQ48963833
Experimental thromboembolic stroke in cynomolgus monkeyQ49048442
Edaravone (3-Methyl-1-Phenyl-2-Pyrazolin-5-one), A Novel Free Radical Scavenger, for Treatment of Cardiovascular DiseasesQ56911324
Strength Training Associated with Task-Oriented Training to Enhance Upper-Limb Motor Function in Elderly Patients with Mild Impairment After StrokeQ59676728
NXY-059 for the treatment of acute ischemic strokeQ80768385
Astrocytes promote myelination in response to electrical impulsesQ24547572
Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeysQ24654374
Ligustrazine monomer against cerebral ischemia/reperfusion injuryQ26862626
Pathobiology of ischaemic stroke: an integrated viewQ28141682
Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagyQ28286093
NXY-059 for acute ischemic strokeQ28296316
Mechanisms and functional implications of adult neurogenesisQ29547295
Mammalian neural stem cellsQ29547657
1,026 experimental treatments in acute strokeQ29615509
Neuronal replacement from endogenous precursors in the adult brain after strokeQ29615772
Functional neurogenesis in the adult hippocampusQ29618708
Angiogenesis, neurogenesis and brain recovery of function following injuryQ33718009
Neurogenesis and inflammation after ischemic stroke: what is known and where we go from hereQ34727139
Ischemic stroke treated with Ligusticum chuanxiongQ35197165
Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell InjuryQ36236194
Nitrones as therapeutics in age-related diseasesQ36379608
Temporal profile of astrocytes and changes of oligodendrocyte-based myelin following middle cerebral artery occlusion in diabetic and non-diabetic ratsQ36646844
Life after cerovive: a personal perspective on ischemic neuroprotection in the post-NXY-059 era.Q36810934
Missing steps in the STAIR case: a Translational Medicine perspective on the development of NXY-059 for treatment of acute ischemic strokeQ36853648
Improving outcome after stroke: overcoming the translational roadblockQ37091669
Metabolic downregulation: a key to successful neuroprotection?Q37227909
The role of glutamate in neuronal ischemic injury: the role of spark in fireQ37951747
Understanding secondary injuryQ38018613
Molecular structure, localization, and possible functions of the myelin-associated enzyme 2',3'-cyclic nucleotide 3'-phosphodiesteraseQ39213287
Nitrone-based free radical traps as neuroprotective agents in cerebral ischaemia and other pathologies.Q41301334
Angiogenesis, neurogenesis and neuroplasticity in ischemic strokeQ41423822
Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cellsQ42423397
Neuroprotection and enhanced neurogenesis by tetramethylpyrazine in adult rat brain after focal ischemiaQ43054730
Tetramethylpyrazine promotes proliferation and differentiation of neural stem cells from rat brain in hypoxic condition via mitogen-activated protein kinases pathway in vitroQ43141450
Pharmacokinetics of tetramethylpyrazine in rat blood and brain using microdialysisQ43557159
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)37148
P577publication date2016-11-14
P1433published inScientific ReportsQ2261792
P1476titleTetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
P478volume6

Reverse relations

cites work (P2860)
Q88564646JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain
Q48092764Neuroprotective Effect and Mechanism of Action of Tetramethylpyrazine Nitrone for Ischemic Stroke Therapy
Q99631496Phase I safety, tolerability, and pharmacokinetic studies of tetramethylpyrazine nitrone in healthy Chinese volunteers
Q92344195Production of tetra-methylpyrazine using engineered Corynebacterium glutamicum
Q47327198Tetramethylpyrazine nitrone activates the BDNF/Akt/CREB pathway to promote post-ischaemic neuroregeneration and recovery of neurological functions in rats
Q38979665Tetramethylpyrazine nitrone protects retinal ganglion cells against N-methyl-d-aspartate-induced excitotoxicity.

Search more.