Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.

scientific article

Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/MP500443X
P932PMC publication ID4224523
P698PubMed publication ID25271556
P5875ResearchGate publication ID266380750

P50authorChunqi QianQ61139649
Xiaoyuan ChenQ67123714
Gang NiuQ67137291
Dale O KiesewetterQ67137408
Xuyi YueQ116997808
P2093author name stringYu Wang
Zhe Wang
Lei Zhu
Ying Ma
P2860cites workMatrix metalloproteinasesQ28140451
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Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applicationsQ33692926
Matrix metalloproteinases in tumour invasion and metastasisQ33765792
Matrix metalloproteinases: discrete elevations in essential hypertension and hypertensive end-stage renal diseaseQ33872836
Systematic study of protein detection mechanism of self-assembling 19F NMR/MRI nanoprobes toward rational design and improved sensitivityQ33941540
Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivoQ34032588
A symmetrical fluorous dendron-cyanine dye-conjugated bimodal nanoprobe for quantitative 19F MRI and NIR fluorescence bioimagingQ34052606
In vivo positron emission tomography imaging of protease activity by generation of a hydrophobic product from a noninhibitory protease substrateQ34054507
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly.Q34542211
Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivoQ34861321
In vivo volumetric photoacoustic molecular angiography and therapeutic monitoring with targeted plasmonic nanostars.Q35024494
MMP-Activated Fluorescence Imaging Detects Early Joint Inflammation in Collagen-Antibody-Induced Arthritis in CC-Chemokine Receptor-2-Null Mice, In-VivoQ35094676
In vivo optical imaging of membrane-type matrix metalloproteinase (MT-MMP) activityQ35592730
The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemiaQ35780951
Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies.Q35878888
1H/19F magnetic resonance molecular imaging with perfluorocarbon nanoparticles.Q36336344
Avoiding steric congestion in dendrimer growth through proportionate branching: a twist on da Vinci's rule of tree branchingQ36802314
Gadolinium-modulated 19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imagingQ37003678
Tracking immune cells in vivo using magnetic resonance imagingQ37455363
Development of novel tumor-targeted theranostic nanoparticles activated by membrane-type matrix metalloproteinases for combined cancer magnetic resonance imaging and therapyQ37624281
Characterization of early neovascular response to acute lung ischemia using simultaneous (19)F/ (1)H MR molecular imaging.Q37626285
Quantitative magnetic resonance fluorine imaging: today and tomorrowQ37766558
New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progressionQ37948607
Clinical perspectives of hybrid proton-fluorine magnetic resonance imaging and spectroscopyQ38065015
Imaging of MMP activity in postischemic cardiac remodeling using radiolabeled MMP-2/9 activatable peptide probesQ39228772
Radioactive smart probe for potential corrected matrix metalloproteinase imagingQ39268473
Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticlesQ39498407
MMP-2: expression, activation and inhibitionQ41105675
Multi-chromatic pH-activatable 19F-MRI nanoprobes with binary ON/OFF pH transitions and chemical-shift barcodesQ42606243
Proteinase activity and receptor cleavage: mechanism for insulin resistance in the spontaneously hypertensive rat.Q43134563
CXCR4-targeted and MMP-responsive iron oxide nanoparticles for enhanced magnetic resonance imagingQ43138300
Specific detection and imaging of enzyme activity by signal-amplifiable self-assembling (19)F MRI probesQ43874065
Dual-function probe to detect protease activity for fluorescence measurement and 19F MRI.Q46057320
Paramagnetic relaxation-based 19f MRI probe to detect protease activityQ46836886
Relaxometric studies of gadolinium-functionalized perfluorocarbon nanoparticles for MR imaging.Q50623896
On-off regulation of 19F magnetic resonance signals based on pH-sensitive PEGylated nanogels for potential tumor-specific smart 19F MRI probes.Q50923531
A tumor-environment-responsive nanocarrier that evolves its surface properties upon sensing matrix metalloproteinase-2 and initiates agglomeration to enhance T₂ relaxivity for magnetic resonance imagingQ57184908
Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imagingQ57185539
Peripheral blood level alterations of TIMP-1, MMP-2 and MMP-9 in patients with type 1 diabetesQ77067755
Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivoQ79792625
Alterations in peripheral blood levels of TIMP-1, MMP-2, and MMP-9 in patients with type-2 diabetesQ80349976
Potent mechanism-based inhibitors for matrix metalloproteinasesQ80940021
Heat-initiated detection for reduced glutathione with ¹⁹F NMR probes based on modified gold nanoparticlesQ85484542
P4510describes a project that usesmagnetic resonance imagingQ161238
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)4208-4217
P577publication date2014-10-13
P1433published inMolecular PharmaceuticsQ3011140
P1476titleNovel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.
P478volume11

Reverse relations

cites work (P2860)
Q64086888Accelerated F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement
Q55086950Fluorinated EuII-based multimodal contrast agent for temperature- and redox-responsive magnetic resonance imaging.
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Q36373909Multifunctional nanoprobes for both fluorescence and 19F magnetic resonance imaging
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Q38761680Small BODIPY Probes for Combined Dual (19) F MRI and Fluorescence Imaging
Q38798242The N-terminus of the yeast G protein-coupled receptor Ste2p plays critical roles in surface expression, signaling, and negative regulation
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