The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C.

scientific article published in October 2000

The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M002603200
P698PubMed publication ID10880509
P5875ResearchGate publication ID12437588

P50authorMarc ParmentierQ1444262
P2093author name stringAkerman KE
Kukkonen JP
Detheux M
Lund PE
Uustare A
Shariatmadari R
P2860cites workDirect activation of human TRPC6 and TRPC3 channels by diacylglycerolQ22001504
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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviorQ24315738
Coassembly of TRP and TRPL Produces a Distinct Store-Operated ConductanceQ24316255
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activityQ24317782
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositidesQ24529828
Cloning and functional expression of a human Ca2+-permeable cation channel activated by calcium store depletionQ28115710
Significance of PIP2 hydrolysis and regulation of phospholipase C isozymesQ28618735
Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systemsQ34854732
TRP2: a candidate transduction channel for mammalian pheromone sensory signaling.Q36370749
Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedbackQ36411634
Muscarinic receptor-operated Ca2+ influx in transfected fibroblast cells is independent of inositol phosphates and release of intracellular Ca2+.Q36784360
On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins.Q37088812
'Quantal' Ca2+ release and the control of Ca2+ entry by inositol phosphates--a possible mechanismQ37919365
The second extracellular loop of CCR5 is the major determinant of ligand specificity.Q39427062
Sequential activation of different Ca2+ entry pathways upon cholinergic stimulation in mouse pancreatic acinar cellsQ39489651
Receptor-activated Ca2+ influx: how many mechanisms for how many channels?Q40752868
Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channelsQ40896605
Muscarinic receptor activation of arachidonate-mediated Ca2+ entry in HEK293 cells is independent of phospholipase C.Q40992449
Ionic currents underlying HTRP3 mediated agonist-dependent Ca2+ influx in stably transfected HEK293 cellsQ41060052
Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled ReceptorQ41323162
Receptor-activated Ca2+ inflow in animal cells: a variety of pathways tailored to meet different intracellular Ca2+ signalling requirementsQ41860670
Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologuesQ41964579
Evidence for two pathways of receptor-mediated Ca2+ entry in hepatocytesQ42069402
The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytesQ42165243
Histamine-induced Ca2+ entry precedes Ca2+ mobilization in bovine adrenal chromaffin cellsQ42256380
Sphingosine mobilizes intracellular calcium in human neutrophilsQ42288358
Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion.Q42795855
Slow calcium-dependent inactivation of depletion-activated calcium current. Store-dependent and -independent mechanisms.Q45970573
Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptorQ46074332
Distribution of orexin receptor mRNA in the rat brainQ48347303
2APB, 2-aminoethoxydiphenyl borate, a membrane-penetrable modulator of Ins(1,4,5)P3-induced Ca2+ releaseQ48605432
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.Q52568167
Second messenger-activated calcium influx in rat peritoneal mast cells.Q54104148
Inositol 1,3,4,5-tetrakisphosphate activates an endothelial Ca2+-permeable channelQ59066937
P433issue40
P407language of work or nameEnglishQ1860
P304page(s)30806-30812
P577publication date2000-10-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C
P478volume275