Inferring positive selection in humans from genomic data

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Inferring positive selection in humans from genomic data is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1050086689
P356DOI10.1186/S13323-015-0023-1
P932PMC publication ID4381672
P698PubMed publication ID25834723
P5875ResearchGate publication ID274396835

P2093author name stringWolfgang Stephan
Andreas Wollstein
P2860cites workThe Correlation between Relatives on the Supposition of Mendelian InheritanceQ7727667
Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan dataQ21144969
The role of geography in human adaptationQ21145001
The origin of European cattle: evidence from modern and ancient DNAQ21147044
Genetic adaptation to high altitude in the Ethiopian highlandsQ21184015
The genetic architecture of adaptations to high altitude in EthiopiaQ21563365
A map of recent positive selection in the human genomeQ21563624
The distribution of fitness effects of new deleterious amino acid mutations in humansQ22065135
Evidence for variable selective pressures at MC1RQ22066136
Potential etiologic and functional implications of genome-wide association loci for human diseases and traitsQ22066284
Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in south Europeans.Q50485708
An improved method for estimating the rate of fixation of favorable mutations based on DNA polymorphism data.Q52332693
The geometry of adaptationQ59057231
The theory of a clineQ79556269
The signature of positive selection on standing genetic variationQ82187447
A new test for detecting recent positive selection that is free from the confounding impacts of demographyQ84740295
Fitness and its role in evolutionary geneticsQ22122004
The genetic theory of adaptation: a brief historyQ22122021
Initial sequence of the chimpanzee genome and comparison with the human genomeQ22122468
Detecting recent positive selection in the human genome from haplotype structureQ22122511
Genetics of Lactase Persistence and Lactose IntoleranceQ22255636
Genome-wide detection and characterization of positive selection in human populationsQ23000444
A test of neutral molecular evolution based on nucleotide dataQ24532207
Statistical method for testing the neutral mutation hypothesis by DNA polymorphismQ24532326
Statistical tests of neutrality of mutationsQ24532850
The effect of deleterious mutations on neutral molecular variationQ24532876
Genetic signatures of strong recent positive selection at the lactase geneQ24533797
Soft sweeps: molecular population genetics of adaptation from standing genetic variationQ24544984
Hitchhiking under positive Darwinian selectionQ24548125
Genome-wide association studies for complex traits: consensus, uncertainty and challengesQ24550632
Adaptations to local environments in modern human populationsQ24563289
Sequencing of 50 human exomes reveals adaptation to high altitudeQ24599025
A map of human genome variation from population-scale sequencingQ24617794
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlandersQ24623640
Hundreds of variants clustered in genomic loci and biological pathways affect human heightQ24630979
Out of Africa: modern human origins special feature: explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from AfricaQ24646508
Signals of recent positive selection in a worldwide sample of human populationsQ24651949
Convergent adaptation of human lactase persistence in Africa and EuropeQ24655819
A haplotype map of the human genomeQ24679827
Two routes to functional adaptation: Tibetan and Andean high-altitude nativesQ24681902
Recent human adaptation: genomic approaches, interpretation and insightsQ26830849
Methods to detect selection on noncoding DNAQ26852755
Human pigmentation genes under environmental selectionQ26865756
The International HapMap ProjectQ27860695
On the number of segregating sites in genetical models without recombinationQ28206543
A human genome diversity cell line panelQ28214742
Constructing genomic maps of positive selection in humans: where do we go from here?Q36825567
Pattern of polymorphism after strong artificial selection in a domestication eventQ36986615
Correcting estimators of theta and Tajima's D for ascertainment biases caused by the single-nucleotide polymorphism discovery processQ37102670
A population genomic approach to map recent positive selection in model speciesQ37216758
From evolutionary genetics to human immunology: how selection shapes host defence genesQ37642585
On detecting incomplete soft or hard selective sweeps using haplotype structureQ37716134
Genetic hitchhiking versus background selection: the controversy and its implicationsQ37716247
Colorful DNA polymorphisms in humansQ38099134
Genetic architecture of quantitative traits and complex diseases.Q38167224
Impact of range expansions on current human genomic diversityQ38243238
The Red Queen's long race: human adaptation to pathogen pressureQ38244562
Population differentiation as a test for selective sweepsQ39682956
Effects of population size and mutation rate on the evolution of mutational robustnessQ39789176
Detecting a local signature of genetic hitchhiking along a recombining chromosome.Q41778534
Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphismsQ41821274
The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs.Q41827047
SweeD: likelihood-based detection of selective sweeps in thousands of genomesQ41920946
Informativeness of genetic markers for inference of ancestry.Q42035885
Second-order moments of segregating sites under variable population sizeQ42526432
Consequences of population structure on genes under balancing selectionQ42660584
Positive selection can create false hotspots of recombinationQ42712694
The structure of linkage disequilibrium around a selective sweepQ42874971
A Neutral Explanation for the Correlation of Diversity with Recombination Rates in HumansQ42927602
Analytical results on the neutral non-equilibrium allele frequency spectrum based on diffusion theoryQ43438404
Evidence for polygenic adaptation to pathogens in the human genomeQ45718642
Stochastic patterns of polymorphism after a selective sweep over a subdivided populationQ46200177
Detecting strong positive selection in the genomeQ46361017
Non-equilibrium theory of the allele frequency spectrumQ46543740
Gene flow and natural selection in oceanic human populations inferred from genome-wide SNP typingQ46704622
Molecular genetics of human pigmentation diversityQ28238551
The hitch-hiking effect of a favourable geneQ28241578
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNAQ28244310
Recent and ongoing selection in the human genomeQ28253753
Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its applicationQ28268693
Genetic evidence for the convergent evolution of light skin in Europeans and East AsiansQ28279959
Genetic evidence for high-altitude adaptation in TibetQ28282435
SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humansQ28287208
Adaptive protein evolution at the Adh locus in DrosophilaQ28302478
Evolution of lactase persistence: an example of human niche constructionQ28742209
The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptationQ28744550
Positive natural selection in the human lineageQ29614585
The effect of change in population size on DNA polymorphismQ29614672
Molecular signatures of natural selectionQ29614731
Natural selection on protein-coding genes in the human genomeQ29615352
Whole-genome patterns of common DNA variation in three human populationsQ29616283
Interrogating a high-density SNP map for signatures of natural selectionQ29618614
The "hitchhiking effect" revisitedQ30004196
Detecting natural selection in genomic dataQ30701255
Population genetic analysis of ascertained SNP dataQ30978101
Genomic regions exhibiting positive selection identified from dense genotype dataQ31013514
A new approach for using genome scans to detect recent positive selection in the human genomeQ33288248
Assessing the evolutionary impact of amino acid mutations in the human genomeQ33339383
An investigation of the statistical power of neutrality tests based on comparative and population genetic dataQ33376943
Searching for footprints of positive selection in whole-genome SNP data from nonequilibrium populationsQ33560640
Genome-wide signals of positive selection in human evolutionQ33657712
Understanding and using quantitative genetic variationQ33743116
Identifying positive selection candidate loci for high-altitude adaptation in Andean populations.Q33801169
Simultaneous inference of selection and population growth from patterns of variation in the human genomeQ33841217
The hitchhiking effect on the site frequency spectrum of DNA polymorphisms.Q33965382
A population genetic signal of polygenic adaptationQ34015195
Using environmental correlations to identify loci underlying local adaptationQ34082239
A composite of multiple signals distinguishes causal variants in regions of positive selectionQ34091559
The genetic architecture of quantitative traitsQ34100924
Classic selective sweeps were rare in recent human evolutionQ34165349
Ascertainment bias in studies of human genome-wide polymorphism.Q34206539
Learning about human population history from ancient and modern genomes.Q34208814
Evidence of widespread selection on standing variation in Europe at height-associated SNPsQ34294735
Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in EuropeansQ34305121
Andean and Tibetan patterns of adaptation to high altitudeQ34324271
Adaptive fixation in two-locus models of stabilizing selection and genetic driftQ34336704
Genetical structure of populationsQ34352694
Selection and adaptation in the human genomeQ34356042
The impact of whole-genome sequencing on the reconstruction of human population historyQ34401955
Lactase persistence alleles reveal partial East African ancestry of southern African Khoe pastoralists.Q34413753
High genomic deleterious mutation rates in hominidsQ34491535
Allele frequency distribution under recurrent selective sweepsQ34587933
The hitchhiking effect on linkage disequilibrium between linked neutral lociQ34588489
Signatures of positive selection in genes associated with human skin pigmentation as revealed from analyses of single nucleotide polymorphisms.Q34603456
Homozygosity and linkage disequilibrium.Q34614942
Linkage disequilibrium as a signature of selective sweepsQ34645314
How reliable are empirical genomic scans for selective sweeps?Q34655368
Genomic signatures of positive selection in humans and the limits of outlier approachesQ34881979
Adaptive evolution of loci covarying with the human African Pygmy phenotypeQ36095609
Adaptation – not by sweeps aloneQ36299201
Limited evidence for classic selective sweeps in African populationsQ36466280
Detecting signatures of selection through haplotype differentiation among hierarchically structured populationsQ36643912
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)5
P577publication date2015-04-01
P1433published inInvestigative GeneticsQ15816652
P1476titleInferring positive selection in humans from genomic data
P478volume6

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cites work (P2860)
Q58735723A Gene-Based Positive Selection Detection Approach to Identify Vaccine Candidates Using as a Test Case Protozoan Pathogen
Q47948028Detecting gene subnetworks under selection in biological pathways
Q92951697Genetic Variation in Human Gene Regulatory Factors Uncovers Regulatory Roles in Local Adaptation and Disease
Q33825082Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy
Q38631839Genomic resources and their influence on the detection of the signal of positive selection in genome scans
Q36735472Heterochrony as Diachronically Modified Cell-Cell Interactions
Q38902399Heterozygosity increases microsatellite mutation rate
Q28082728Population genetic studies in the genomic sequencing era
Q35957460S/HIC: Robust Identification of Soft and Hard Sweeps Using Machine Learning
Q53406877Selection on the regulation of sympathetic nervous activity in humans and chimpanzees.

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