Schizophrenia: Evidence implicating hippocampal GluN2B protein and REST epigenetics in psychosis pathophysiology

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Schizophrenia: Evidence implicating hippocampal GluN2B protein and REST epigenetics in psychosis pathophysiology is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.NEUROSCIENCE.2015.07.038
P932PMC publication ID5550101
P698PubMed publication ID26211447

P2093author name stringC A Tamminga
R S Zukin
P2860cites workHippocampal deformities in the unaffected siblings of schizophrenia subjects.Q48131112
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Regional specificity of hippocampal volume reductions in first-episode schizophrenia.Q52000520
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REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.Q52049234
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Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophreniaQ34590284
Hippocampal volume is reduced in schizophrenia and schizoaffective disorder but not in psychotic bipolar I disorder demonstrated by both manual tracing and automated parcellation (FreeSurfer).Q34700980
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Hippocampal network dynamics constrain the time lag between pyramidal cells across modified environments.Q37131466
Epigenetic mechanisms mediating the long-term effects of maternal care on development.Q37145451
Polycomb complexes and epigenetic statesQ37148660
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Selective abnormal modulation of hippocampal activity during memory formation in first-episode psychosisQ38395289
Reduced hippocampal activation during encoding and recognition of words in schizophrenia patientsQ38427558
Impaired hippocampal recruitment during normal modulation of memory performance in schizophreniaQ38430593
NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII.Q40359235
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Creating a false memory in the hippocampusQ42281296
Early life experience alters response of adult neurogenesis to stressQ42465236
Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans ratsQ42525938
Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses.Q43757912
Temporal lobe metabolic differences in medication-free outpatients with schizophrenia via the PET-600.Q43782953
Left hemisphere dysfunction and left hemisphere overactivation in schizophreniaQ44608634
Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity.Q45181366
Hippocampal volumes in schizophrenic twinsQ46211788
Dissociation between medial temporal lobe and basal ganglia memory systems in schizophrenia.Q46436004
Neonatal isolation delays the developmental decline of long-term depression in the CA1 region of rat hippocampusQ46681207
Dorsal hippocampus, CA3, and CA1 lesions disrupt temporal sequence completionQ46735145
Transgenic inhibition of synaptic transmission reveals role of CA3 output in hippocampal learningQ46792400
NR2A-/- mice lack long-term potentiation but retain NMDA receptor and L-type Ca2+ channel-dependent long-term depression in the juvenile superior colliculus.Q46852225
Communal nesting, an early social enrichment, affects social competences but not learning and memory abilities at adulthoodQ48108720
CA3 NMDA receptors are required for experience-dependent shifts in hippocampal activityQ48118107
P407language of work or nameEnglishQ1860
P921main subjectpathophysiologyQ1135939
psychosisQ170082
schizophreniaQ41112
P1104number of pages10
P304page(s)233-242
P577publication date2015-07-23
P1433published inNeuroscienceQ15708571
P1476titleSchizophrenia: Evidence implicating hippocampal GluN2B protein and REST epigenetics in psychosis pathophysiology
P478volume309

Reverse relations

cites work (P2860)
Q50015658A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia.
Q41195184Abnormalities of signal transduction networks in chronic schizophrenia
Q54220901Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro.
Q48258093Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia
Q92442047News about the Role of the Transcription Factor REST in Neurons: From Physiology to Pathology
Q30355619Spatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia.

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