Nanomolar concentrations of epothilone D inhibit the proliferation of glioma cells and severely affect their tubulin cytoskeleton

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Nanomolar concentrations of epothilone D inhibit the proliferation of glioma cells and severely affect their tubulin cytoskeleton is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1050665044
P356DOI10.1023/B:NEON.0000003679.40609.63
P698PubMed publication ID14686728

P2093author name stringDietzmann K
Kirches E
Kropf S
Mawrin C
Kanakis D
Dietzmann A
P2860cites workEpothilone B stabilizes microtubuli of macrophages like taxol without showing taxol-like endotoxin activityQ28247147
Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.Q33614661
Molecular effects of paclitaxel: myths and reality (a critical review).Q33725219
Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activityQ33911979
Subcellular distribution of epothilones in human tumor cellsQ33944889
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.Q34722347
Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.Q36271699
The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude miceQ36541279
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacyQ43606278
New taxanes and epothilone derivatives in clinical trialsQ43997123
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part I: Evaluation of test-specific variablesQ48483676
Thermodynamics of ligand-induced assembly of tubulin.Q52390474
A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothiloneQ73816714
P433issue2
P921main subjectcytoskeletonQ154626
P304page(s)99-106
P577publication date2003-11-01
P1433published inJournal of Neuro-OncologyQ15752119
P1476titleNanomolar concentrations of epothilone D inhibit the proliferation of glioma cells and severely affect their tubulin cytoskeleton
P478volume65

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cites work (P2860)
Q28574198Epothilone D, a microtubule-stabilizing compound, inhibits neointimal hyperplasia after rat carotid artery injury by cell cycle arrest via regulation of G1-checkpoint proteins
Q37236419Epothilones: a novel class of microtubule-stabilizing drugs for the treatment of cancer
Q91603671G2/M inhibitors as pharmacotherapeutic opportunities for glioblastoma: the old, the new, and the future
Q37688393GBM-associated mutations and altered protein expression are more common in young patients
Q39214217Natural Compounds as Modulators of Cell Cycle Arrest: Application for Anticancer Chemotherapies.
Q50239832Neurotransmitter noradrenaline downregulate cytoskeletal protein expression of VSMCs
Q36187046Novel therapeutics in adult malignant brain gliomas
Q37284300Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases
Q44092540Systemic sagopilone (ZK-EPO) treatment of patients with recurrent malignant gliomas.

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