Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome

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Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...629088R
P356DOI10.1371/JOURNAL.PONE.0029088
P932PMC publication ID3237596
P698PubMed publication ID22194994
P5875ResearchGate publication ID51921109

P50authorJacqueline StockleyQ56697387
Prabhakar RajanQ60976609
Cedric SimillionQ37368009
David J ElliottQ38323411
Hing Y LeungQ40453449
P2093author name stringMichael Q Zhang
Chaolin Zhang
Caroline Dalgliesh
Craig N Robson
Gabriela Kalna
Kelly Armstrong
Luke Gaughan
Phillippa J Carling
Sushma N Grellscheid
Thomas Buist
P2860cites workAn integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progressionQ24313269
The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancerQ24318348
The program of androgen-responsive genes in neoplastic prostate epitheliumQ24535711
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Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer modelQ24644698
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Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancerQ24670460
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Statistical significance for genomewide studiesQ24681264
Transcriptional programs activated by exposure of human prostate cancer cells to androgenQ24802648
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Alternative isoform regulation in human tissue transcriptomesQ27861118
Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cellsQ28217743
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarraysQ28235146
Molecular determinants of resistance to antiandrogen therapyQ28236889
The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partnersQ28269653
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencingQ29547470
Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicingQ30439381
Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genesQ31892738
A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants.Q33286653
Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cellsQ34042356
The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferasesQ34295310
Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathwaysQ34562010
Exon arrays provide accurate assessments of gene expressionQ35906488
Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatmentQ37134137
The meaning of nonsenseQ37182097
Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screenQ37262522
Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitroQ37332423
Alternative splicing and biological heterogeneity in prostate cancerQ37573399
The changing therapeutic landscape of castration-resistant prostate cancerQ37913983
The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptorQ38293539
Identification and validation of novel androgen-regulated genes in prostate cancerQ38341527
Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.Q38344704
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesisQ39538459
Microarray coupled to quantitative RT-PCR analysis of androgen-regulated genes in human LNCaP prostate cancer cellsQ39861422
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.Q40089132
Differential regulation of clusterin and its isoforms by androgens in prostate cellsQ40200381
Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteinsQ40248475
Identification of a novel Wee1 isoformQ42816283
Coordinate regulation of transcription and splicing by steroid receptor coregulatorsQ44177314
Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse modelQ46616183
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjecttranscriptomeQ252857
P304page(s)e29088
P577publication date2011-12-14
P1433published inPLOS OneQ564954
P1476titleIdentification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome
P478volume6

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cites work (P2860)
Q33855473A mutation in a splicing factor that causes retinitis pigmentosa has a transcriptome-wide effect on mRNA splicing.
Q38365327A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation.
Q38132132Alternative splicing programs in prostate cancer
Q42880656Androgen receptor genomic regulation
Q57135534Androgen-dependent alternative mRNA isoform expression in prostate cancer cells
Q83227835Androgen-regulated transcription of drives alternative splicing patterns in prostate cancer
Q35543453Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells
Q35063756Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration
Q53779715Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.
Q38757500Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
Q39341456Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases
Q39984274Lyn tyrosine kinase regulates androgen receptor expression and activity in castrate-resistant prostate cancer
Q39093621Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy
Q43119456Novel 5' fusion partners of ETV1 and ETV4 in prostate cancer
Q38909020Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer
Q39145696Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing
Q39223617RNA splicing and splicing regulator changes in prostate cancer pathology
Q40393450The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells.
Q38259961The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer.
Q33922376The role of mRNA splicing in prostate cancer

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