Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM.

scientific article

Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YMETH.2016.02.007
P932PMC publication ID4848141
P698PubMed publication ID26884261

P50authorJoachim FrankQ28833112
Abbas OurmazdQ88035458
P2860cites workStructure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29Q24293558
Conformations of macromolecules and their complexes from heterogeneous datasetsQ27024241
Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation processQ27639298
Locking and unlocking of ribosomal motionsQ27641675
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sitesQ27666149
Structural characterization of mRNA-tRNA translocation intermediatesQ27678288
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunitQ27680505
Structure of the TRPV1 ion channel determined by electron cryo-microscopyQ27680759
Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EMQ27698054
Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPaseQ27700838
Ribosome. The structure of the human mitochondrial ribosomeQ28115987
Ribosome structure and the mechanism of translationQ28209121
RELION: implementation of a Bayesian approach to cryo-EM structure determinationQ29547673
A ratchet-like inter-subunit reorganization of the ribosome during translocationQ29619258
Likelihood-based classification of cryo-EM images using FREALIGNQ30352230
Nonlinear Laplacian spectral analysis for time series with intermittency and low-frequency variabilityQ30505948
Trajectories of the ribosome as a Brownian nanomachineQ30608405
Particle migration analysis in iterative classification of cryo-EM single-particle dataQ30873021
Heterogeneity of large macromolecular complexes revealed by 3D cryo-EM variance analysisQ33392802
Automated multi-model reconstruction from single-particle electron microscopy dataQ33525212
Structure and dynamics of a processive Brownian motor: the translating ribosomeQ34104360
Structure of a mammalian ryanodine receptorQ34451822
Capturing transition paths and transition states for conformational rearrangements in the ribosomeQ34727629
Structural snapshots of actively translating human ribosomesQ35608572
Cryo-EM: A Unique Tool for the Visualization of Macromolecular ComplexityQ35638563
Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.Q35729265
A Bayesian view on cryo-EM structure determination.Q35859527
Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromoleculeQ36567293
Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructionsQ36698585
Structure of ratcheted ribosomes with tRNAs in hybrid statesQ36964252
Structural dynamics of the ribosomeQ37291893
Ribosome structure and dynamics during translocation and terminationQ37700669
Spontaneous intersubunit rotation in single ribosomes.Q41208124
Story in a sample-the potential (and limitations) of cryo-electron microscopy applied to molecular machinesQ41611006
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopyQ41618424
Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections.Q41623466
Unsupervised classification of single particles by cluster tracking in multi-dimensional spaceQ41625759
Ab initio structure determination from electron microscopic images of single molecules coexisting in different functional statesQ41792141
Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosomeQ41914975
Bayesian algorithms for recovering structure from single-particle diffraction snapshots of unknown orientation: a comparison.Q51539659
Classification of heterogeneous electron microscopic projections into homogeneous subsets.Q51912354
Correspondence analysis of aligned images of biological particles.Q52714012
Use of multivariate statistics in analysing the images of biological macromoleculesQ52745385
Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization.Q54449974
From cryo-EM, multiple protein structures in one shotQ79460802
Coupling of ribosomal L1 stalk and tRNA dynamics during translation elongationQ81254271
P921main subjectcryogenic electron microscopyQ5190506
P304page(s)61-67
P577publication date2016-02-13
P1433published inMethodsQ6823859
P1476titleContinuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM.
P478volume100

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