scholarly article | Q13442814 |
P819 | ADS bibcode | 2012PLoSO...730075P |
P356 | DOI | 10.1371/JOURNAL.PONE.0030075 |
P932 | PMC publication ID | 3267722 |
P698 | PubMed publication ID | 22299030 |
P5875 | ResearchGate publication ID | 239785274 |
P50 | author | Nicholas W Morrell | Q60960702 |
Ian M. Adcock | Q38803002 | ||
P2093 | author name string | Paul D Upton | |
Mark J D Griffiths | |||
Stephen J Wort | |||
Rachel J Davies | |||
Dongmin Shao | |||
John E S Park | |||
Patricia Desouza | |||
P2860 | cites work | BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo | Q24307458 |
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells | Q24309588 | ||
Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia | Q64045883 | ||
Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation | Q68069838 | ||
Bosentan therapy for pulmonary arterial hypertension | Q77801473 | ||
Signaling by ALK5 mediates TGF-beta-induced ET-1 expression in endothelial cells: a role for migration and proliferation | Q80005826 | ||
Localization of endothelin receptors in bleomycin-induced pulmonary fibrosis in the rat | Q80852841 | ||
Transforming growth factor-beta induces endothelin-1 expression through activation of the Smad signaling pathway | Q81663164 | ||
Endothelin receptor expression in idiopathic pulmonary arterial hypertension: effect of bosentan and epoprostenol treatment | Q83619736 | ||
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. | Q42823613 | ||
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor | Q43952396 | ||
Signaling molecules in nonfamilial pulmonary hypertension | Q44305028 | ||
Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy | Q45091702 | ||
Endothelin-1 enhances cell migration via matrix metalloproteinase-9 up-regulation in brain astrocytes | Q48258310 | ||
Proliferative stimulation of the vascular Endothelin-1 axis in vitro and ex vivo by infection with Chlamydia pneumoniae. | Q52596124 | ||
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage. | Q52927963 | ||
Bone morphogenic protein-9 stimulates endothelin-1 release from human pulmonary microvascular endothelial cells: a potential mechanism for elevated ET-1 levels in pulmonary arterial hypertension. | Q54665302 | ||
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension | Q55670914 | ||
Deletion of Endothelial Cell Endothelin B Receptors Does Not Affect Blood Pressure or Sensitivity to Salt | Q56987910 | ||
Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension | Q57149168 | ||
Endothelin-1 in the lungs of patients with pulmonary hypertension | Q58622178 | ||
Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats | Q61712109 | ||
Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling | Q24313348 | ||
BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes | Q24315830 | ||
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells | Q24315838 | ||
The selectivity of protein kinase inhibitors: a further update | Q24654622 | ||
Bone morphogenetic protein-9 is a circulating vascular quiescence factor | Q24657942 | ||
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6 | Q28140674 | ||
Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway | Q28243967 | ||
BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis | Q28289169 | ||
Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension | Q28572271 | ||
The specificities of protein kinase inhibitors: an update | Q30014834 | ||
ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression | Q30811602 | ||
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension | Q34043809 | ||
BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension | Q34180789 | ||
Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts. | Q34402832 | ||
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family | Q35559673 | ||
Role of endothelin-1 in neovascularization of ovarian carcinoma | Q35829525 | ||
Evidence for the presence of endothelin ETA receptors in endothelial cells in situ on the aortic side of porcine aortic valve | Q35872700 | ||
IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation | Q36497326 | ||
Drug Insight: endothelin-receptor antagonists for pulmonary arterial hypertension in systemic rheumatic diseases | Q36577383 | ||
Pulmonary hypertension due to BMPR2 mutation: a new paradigm for tissue remodeling? | Q36634716 | ||
Endothelin receptor antagonism and cancer | Q37428046 | ||
Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites | Q37433354 | ||
Controlling of bone morphogenetic protein signaling | Q37671293 | ||
The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension | Q37854945 | ||
ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif | Q38855307 | ||
Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells | Q39635816 | ||
Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase | Q39665350 | ||
Functional implication of BMP4 expression on angiogenesis in malignant melanoma | Q40195197 | ||
Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. | Q41946175 | ||
Differential effects of BMP signaling on parvalbumin and somatostatin interneuron differentiation | Q42040440 | ||
Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity | Q42442261 | ||
Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cells | Q42820799 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | endothelium | Q111140 |
P304 | page(s) | e30075 | |
P577 | publication date | 2012-01-27 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production | |
P478 | volume | 7 |
Q47856805 | ALK1 signaling in development and disease: new paradigms. |
Q38140116 | Activin receptor-like kinase 1 as a target for anti-angiogenesis therapy. |
Q34467651 | An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis |
Q36498604 | BMP signaling in mesenchymal stem cell differentiation and bone formation |
Q28296361 | BMP9 is a proliferative and survival factor for human hepatocellular carcinoma cells |
Q36796379 | BMP9 signaling in stem cell differentiation and osteogenesis |
Q36731449 | BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells |
Q37561236 | Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension. |
Q37080802 | Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence |
Q38332401 | Emerging roles of BMP9 and BMP10 in hereditary hemorrhagic telangiectasia. |
Q34982792 | Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells |
Q33738647 | Endothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling. |
Q37671796 | Endothelial signaling and the molecular basis of arteriovenous malformation |
Q36378875 | Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. |
Q38627317 | Morphogenic Peptides in Regeneration of Load Bearing Tissues |
Q37215728 | Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension. |
Q38199567 | Potential roles of bone morphogenetic protein (BMP)-9 in human liver diseases |
Q36473791 | The Prodomain-Containing BMP9 Produced from a Stable Line Effectively Regulates the Differentiation of Mesenchymal Stem Cells |
Q38218507 | The role of BMPs in endothelial cell function and dysfunction |
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