Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk

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Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1152359K
P356DOI10.1371/JOURNAL.PONE.0152359
P932PMC publication ID4811433
P698PubMed publication ID27023073

P50authorCecile JanssensQ58477081
Suman KunduQ37842381
P2093author name stringJannigje G Kers
P2860cites workEstimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studiesQ30834328
The potential of genes and other markers to inform about riskQ33718762
Polygenes, risk prediction, and targeted prevention of breast cancerQ81523323
Public health implications from COGS and potential for risk stratification and screeningQ86499074
Relationship between resistant hypertension and arterial stiffness assessed by brachial-ankle pulse wave velocity in the older patientQ34166925
Evaluation of the discriminative accuracy of genomic profiling in the prediction of common complex diseasesQ34328816
Combined associations of genetic and environmental risk factors: implications for prevention of breast cancerQ34736112
Genome-based prediction of common diseases: advances and prospectsQ34851798
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Polygenic susceptibility to prostate and breast cancer: implications for personalised screeningQ34977428
Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screeningQ35136955
Waist circumference and insulin resistance: a community based cross sectional study on reproductive aged Iranian womenQ35207065
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosisQ35602297
High-sensitivity C-reactive protein to detect metabolic syndrome in a centrally obese population: a cross-sectional analysisQ35984531
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Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer riskQ36858843
Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetesQ37149397
Personalized screening for cancers: should we consider polygenic profiling?Q37333975
Incorporating genomics into breast and prostate cancer screening: assessing the implicationsQ37614763
Variations in predicted risks in personal genome testing for common complex diseasesQ39395332
Predictive testing for complex diseases using multiple genes: fact or fiction?Q40306679
Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and resultsQ41110676
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesBayes' theoremQ182505
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)e0152359
P577publication date2016-03-29
P1433published inPLOS OneQ564954
P1476titleConstructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk
P478volume11

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Q89561075Cost-Effectiveness of Risk-Stratified Colorectal Cancer Screening Based on Polygenic Risk: Current Status and Future Potentialcites workP2860

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