NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy

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NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PBIO.1001409
P932PMC publication ID3479101
P698PubMed publication ID23109907
P5875ResearchGate publication ID232739674

P50authorBryan D. CrawfordQ41191609
P2093author name stringClarissa A Henry
Michelle F Goody
Andre Khalil
Meghan W Kelly
Christine J Reynolds
P2860cites workNicotinamide riboside kinase structures reveal new pathways to NAD+Q21145891
p53 activation by knockdown technologiesQ21563456
Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGEQ24301093
Spatial and temporal expression of the beta1D integrin during mouse developmentQ24316487
Mutations in the integrin alpha7 gene cause congenital myopathyQ24317420
A comparative study of alpha-dystroglycan glycosylation in dystroglycanopathies suggests that the hypoglycosylation of alpha-dystroglycan does not consistently correlate with clinical severityQ24321993
Absence of integrin alpha 7 causes a novel form of muscular dystrophyQ24323372
Integrin ligands at a glanceQ24600618
Paxillin comes of ageQ24657852
The zebrafish candyfloss mutant implicates extracellular matrix adhesion failure in laminin alpha2-deficient congenital muscular dystrophyQ24681141
Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brainQ25255947
Time-lapse analysis and mathematical characterization elucidate novel mechanisms underlying muscle morphogenesisQ27313686
Stages of embryonic development of the zebrafishQ27860947
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humansQ27937147
Dystroglycan is a binding protein of laminin and merosin in peripheral nerveQ28238540
Congenital muscular dystrophies with defective glycosylation of dystroglycan: a population studyQ28238656
Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptorQ28254849
Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrixQ28296676
Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophyQ28297222
Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryoQ28505714
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signalingQ28589349
Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null miceQ28590908
Ral-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migrationQ30393951
Dynamic formation of microenvironments at the myotendinous junction correlates with muscle fiber morphogenesis in zebrafishQ30486454
Basal lamina strengthens cell membrane integrity via the laminin G domain-binding motif of alpha-dystroglycanQ30489039
The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachmentQ30490034
Zebrafish orthologs of human muscular dystrophy genesQ33279472
Drug screening in a zebrafish model of Duchenne muscular dystrophy.Q33845739
Influence of nicotinic acid on serum cholesterol in man.Q33972172
Niaspan treatment induces neuroprotection after strokeQ34079520
An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.Q34091913
The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix depositionQ34225519
Heterozygous deletion of a 2-Mb region including the dystroglycan gene in a patient with mild myopathy, facial hypotonia, oral-motor dyspraxia and white matter abnormalitiesQ34329257
Bridging structure with function: structural, regulatory, and developmental role of lamininsQ34582955
Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathiesQ34766986
A dystroglycan mutation associated with limb-girdle muscular dystrophy.Q34767085
Controlling morpholino experiments: don't stop making antisense.Q34769101
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complexQ34774115
Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic miceQ35083511
Activity and distribution of paxillin, focal adhesion kinase, and cadherin indicate cooperative roles during zebrafish morphogenesisQ35670172
Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophyQ35952091
Characterization of the laminin gene family and evolution in zebrafish.Q51891008
Laminins, via heparan sulfate proteoglycans, participate in zebrafish myotome morphogenesis by modulating the pattern of Bmp responsiveness.Q51894650
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.Q52200996
Soft substrates drive optimal differentiation of human healthy and dystrophic myotubes.Q53295077
Intramuscular degeneration process in Duchenne muscular dystrophy--investigation by longitudinal MR imaging of the skeletal musclesQ68202880
Alpha 6 integrin distribution in human embryonic and adult tissuesQ72050139
Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrinQ83309941
Alpha 6 integrin is important for myogenic stem cell differentiationQ84565378
A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.Q36232550
Molecular and cellular adaptations to chronic myotendinous strain injury in mdx mice expressing a truncated dystrophinQ37089639
Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophyQ37194805
Enhancing cardiovascular disease risk reduction: raising high-density lipoprotein levels.Q37539675
Direct effects of the pathogenic mutation on satellite cell function in muscular dystrophyQ37764976
Dystroglycanopathies: coming into focusQ37852376
Magnetic resonance imaging of skeletal muscle in patients with Duchenne muscular dystrophy--serial axial and sagittal section studiesQ41895993
Overexpression of mini-agrin in skeletal muscle increases muscle integrity and regenerative capacity in laminin-alpha2-deficient mice.Q42478963
Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.Q42489627
Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesisQ42568079
Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression.Q42827022
Niacin improves renal lipid metabolism and slows progression in chronic kidney diseaseQ43251558
Extracellular matrix components direct porcine muscle stem cell behaviorQ43255771
CD117-positive cells in adult human heart are localized in the subepicardium, and their activation is associated with laminin-1 and alpha6 integrin expressionQ44775190
Combined haploid and insertional mutation screen in the zebrafishQ45184325
Laminin alpha1 chain reduces muscular dystrophy in laminin alpha2 chain deficient miceQ45876189
Genes required for functional glycosylation of dystroglycan are conserved in zebrafishQ46480449
Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.Q47073130
Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva.Q47073234
Zebrafish mutants identify an essential role for laminins in notochord formation.Q48297604
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemiaQ48616927
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmuscular dystrophyQ1137767
Danio rerioQ169444
Laminin, gamma 1Q29829508
P304page(s)e1001409
P577publication date2012-10-23
P1433published inPLOS BiologyQ1771695
P1476titleNAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy
P478volume10