Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model

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Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1001388708
P356DOI10.1186/1471-2164-14-848
P932PMC publication ID4046658
P698PubMed publication ID24299188
P5875ResearchGate publication ID259152454

P2093author name stringBin Yang
Jun Ren
Lusheng Huang
Hui Yang
Congying Chen
Chenlong Liu
Zhijun Zeng
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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locusQ24633183
A single IGF1 allele is a major determinant of small size in dogsQ24645092
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChipQ24657931
A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulationQ27340503
SOAP2: an improved ultrafast tool for short read alignmentQ28247469
Regulator of G protein signaling (RGS16) inhibits hepatic fatty acid oxidation in a carbohydrate response element-binding protein (ChREBP)-dependent mannerQ28306219
Mapping the genetic architecture of gene expression in human liverQ28472693
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscleQ28586493
The Creb1 coactivator Crtc1 is required for energy balance and fertilityQ30439853
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequencesQ33265403
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Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: the Erasmus Rucphen Family StudyQ33556143
Tlr2 is critical for diet-induced metabolic syndrome in a murine model.Q33694600
Detection of quantitative trait loci affecting serum cholesterol, LDL, HDL, and triglyceride in pigsQ33959900
Mapping quantitative trait loci in crosses between outbred lines using least squaresQ33962544
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.Q34094985
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndromeQ34209480
Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in miceQ34360242
Mapping determinants of human gene expression by regional and genome-wide associationQ34421244
A genome-wide investigation of expression characteristics of natural antisense transcripts in liver and muscle samples of pigsQ34533893
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Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice.Q35764372
Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.Q35921527
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammalsQ35941759
Mapping complex disease traits with global gene expressionQ35997212
Finding genes and variants for lipid levels after genome-wide association analysisQ36882615
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice.Q37245689
Liver-specific deficiency of serine palmitoyltransferase subunit 2 decreases plasma sphingomyelin and increases apolipoprotein E levelsQ37446891
Integrating expression profiling and whole-genome association for dissection of fat traits in a porcine modelQ41426194
Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.Q42823401
P4510describes a project that usesgenome-wide association studyQ1098876
P407language of work or nameEnglishQ1860
P921main subjectgenome-wide association studyQ1098876
P304page(s)848
P577publication date2013-12-03
P1433published inBMC GenomicsQ15765854
P1476titleGenetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model
P478volume14

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cites work (P2860)
Q34184693A genome-wide association analysis for porcine serum lipid traits reveals the existence of age-specific genetic determinants.
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Q92993037About the existence of common determinants of gene expression in the porcine liver and skeletal muscle
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Q47996900Evaluation of the causality of the low-density lipoprotein receptor gene (LDLR) for serum lipids in pigs
Q40419692Functional and association studies of the cholesteryl ester transfer protein (CETP) gene in a Wannan Black pig model
Q35907693Genetic determinants of pig birth weight variability
Q35677068Genome-Wide Association Analysis for Blood Lipid Traits Measured in Three Pig Populations Reveals a Substantial Level of Genetic Heterogeneity
Q37218558Genome-wide association studies and gene expression profiles of rheumatoid arthritis: An analysis.
Q64064553Genome-wide association studies for 30 haematological and blood clinical-biochemical traits in Large White pigs reveal genomic regions affecting intermediate phenotypes
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Q34460087Sexually dimorphic genetic architecture of complex traits in a large-scale F2 cross in pigs

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