Suppressive effects of irbesartan on inflammation and apoptosis in atherosclerotic plaques of apoE-/- mice: molecular imaging with 14C-FDG and 99mTc-annexin A5.

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Suppressive effects of irbesartan on inflammation and apoptosis in atherosclerotic plaques of apoE-/- mice: molecular imaging with 14C-FDG and 99mTc-annexin A5. is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...989338Z
P356DOI10.1371/JOURNAL.PONE.0089338
P932PMC publication ID3929710
P698PubMed publication ID24586699
P5875ResearchGate publication ID260447971

P50authorYuji KugeQ100497115
Nagara TamakiQ112438951
Songji ZhaoQ121411256
P2093author name stringToru Nakano
Yan Zhao
Yoshikazu Tanaka
Hiroshi Takemoto
Tetsuya Yoshida
Tatsuo Kobayashi
Ayahisa Watanabe
Keita Fukao
P2860cites workComparing angiotensin II receptor blockers on benefits beyond blood pressureQ30360678
Vascular inflammation and the renin-angiotensin systemQ33960784
Localization of deoxyglucose and annexin A5 in experimental atheroma correlates with macrophage infiltration but not lipid deposition in the lesionQ50567621
Comparison of 99mTc-annexin A5 with 18F-FDG for the detection of atherosclerosis in ApoE-/- mice.Q50698610
Anti-inflammatory drug evaluation in ApoE-/- mice by ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging.Q51320363
Angiotensin II Type 1 Receptor Blockade Does Not Enhance Apoptotic Cell Death During Ischemia and Reperfusion in Humans In VivoQ57779571
Increased NADH-Oxidase–Mediated Superoxide Production in the Early Stages of AtherosclerosisQ63365783
Intratumoral distribution of tritiated fluorodeoxyglucose in breast carcinoma: I. Are inflammatory cells important?Q71749211
Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JEQ73575738
Irbesartan reduces common carotid artery intima-media thickness in hypertensive patients when compared with atenolol: the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) studyQ80183412
Rosiglitazone, a PPAR-γ agonist, inhibits VEGF secretion by peripheral blood mononuclear cells and ROS production by human leukocytesQ85071634
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The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studiesQ37158159
In vivo detection and imaging of phosphatidylserine expression during programmed cell deathQ37403902
Improvement of metabolic syndrome by irbesartan via the PPARγ/HGF pathway in apolipoprotein E knockout miceQ38300981
Pioglitazone modulates vascular inflammation in atherosclerotic rabbits noninvasive assessment with FDG-PET-CT and dynamic contrast-enhanced MR imagingQ38469591
A small difference in the molecular structure of angiotensin II receptor blockers induces AT1 receptor-dependent and -independent beneficial effectsQ39674136
Role of reactive oxygen species and Bax in oxidized low density lipoprotein-induced apoptosis of human monocytes.Q40011856
The new angiotensin II receptor antagonist, irbesartan: pharmacokinetic and pharmacodynamic considerationsQ41687064
Angiotensin AT1 receptor antagonist irbesartan decreases lesion size, chemokine expression, and macrophage accumulation in apolipoprotein E-deficient miceQ42656141
Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activityQ42807756
Pleiotropic effects of angiotensin II receptor blocker in hypertensive patientsQ44574645
Attenuation of apoptosis by telmisartan in atherosclerotic plaques of apolipoprotein E-/- mice: evaluation using technetium 99m-annexin A5.Q45069731
Molecular mechanisms of irbesartan suppressing atherosclerosis in high cholesterol-diet apolipoprotein E knock-out miceQ46231951
Stabilization of carotid atheroma assessed by quantitative ultrasound analysis in nonhypercholesterolemic patients with coronary artery diseaseQ46833419
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
atherosclerosisQ12252367
P304page(s)e89338
P577publication date2014-02-19
P1433published inPLOS OneQ564954
P1476titleSuppressive effects of irbesartan on inflammation and apoptosis in atherosclerotic plaques of apoE-/- mice: molecular imaging with 14C-FDG and 99mTc-annexin A5.
P478volume9

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cites work (P2860)
Q50200870A Comparison of [(99m)Tc]Duramycin and [(99m)Tc]Annexin V in SPECT/CT Imaging Atherosclerotic Plaques
Q47866518A review of molecular imaging of atherosclerosis and the potential application of dendrimer in imaging of plaque
Q52577506Annexins in Glaucoma.
Q39728613Detection of atherosclerotic plaques in ApoE-deficient mice using (99m)Tc-duramycin
Q39043966Recent Advances in the Development of PET/SPECT Probes for Atherosclerosis Imaging