Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor

scientific article

Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0968-0896(00)00228-5
P698PubMed publication ID11197334

P50authorRosanna TedescoQ73376252
P2093author name stringStauffer SR
Huang Y
Katzenellenbogen JA
Tedesco R
Coletta CJ
P2860cites workMolecular basis of agonism and antagonism in the oestrogen receptorQ27746278
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifenQ27766417
Rapid chromatographic technique for preparative separations with moderate resolutionQ29391396
Solid-phase synthesis of tetrasubstituted pyrazoles, novel ligands for the estrogen receptorQ30885083
The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding siteQ34419702
Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-betaQ34490307
Hydroxylated 2,3-diarylindenes: synthesis, estrogen receptor binding affinity, and binding orientation considerationsQ42192692
Comparative QSAR analysis of estrogen receptor ligandsQ46485077
Photoaffinity labels for estrogen binding proteins of rat uterusQ47954177
2-Arylindenes and 2-arylindenones: molecular structures and considerations in the binding orientation of unsymmetrical nonsteroidal ligands to the estrogen receptorQ69703169
Regioselective synthesis of 1,3,5-triaryl-4-alkylpyrazoles: novel ligands for the estrogen receptorQ74240190
Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogensQ74659510
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
ligand bindingQ61659151
binding pocketQ61659196
P304page(s)141-150
P577publication date2001-01-01
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleEstrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor
P478volume9