scholarly article | Q13442814 |
P50 | author | David B McGuigan | Q58049555 |
Jason Charng | Q86042189 | ||
Samuel G. Jacobson | Q42410256 | ||
P2093 | author name string | Elise Heon | |
Alejandro J Roman | |||
Artur V Cideciyan | |||
Malgorzata Swider | |||
Mychajlo S Kosyk | |||
Rebecca Sheplock | |||
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Centrosomal-ciliary gene CEP290/NPHP6 mutations result in blindness with unexpected sparing of photoreceptors and visual brain: implications for therapy of Leber congenital amaurosis | Q28305398 | ||
Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy | Q30498337 | ||
Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years | Q30537764 | ||
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A "melanopic" spectral efficiency function predicts the sensitivity of melanopsin photoreceptors to polychromatic lights. | Q34202211 | ||
Melanopsin gene polymorphism I394T is associated with pupillary light responses in a dose-dependent manner | Q34337125 | ||
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Full-field stimulus testing (FST) to quantify visual perception in severely blind candidates for treatment trials. | Q50947743 | ||
Outcome Measures for Clinical Trials of Leber Congenital Amaurosis Caused by the Intronic Mutation in the CEP290 Gene. | Q50998128 | ||
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Disorders of the pupil | Q84160445 | ||
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A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction | Q34541141 | ||
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Photon capture and signalling by melanopsin retinal ganglion cells. | Q34913494 | ||
Pseudo-fovea formation after gene therapy for RPE65-LCA. | Q34999841 | ||
Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy | Q35132187 | ||
Toward a clinical protocol for assessing rod, cone, and melanopsin contributions to the human pupil response | Q35221107 | ||
Pupillary Responses to High-Irradiance Blue Light Correlate with Glaucoma Severity | Q35753239 | ||
Rhodopsin and Melanopsin Contributions to the Early Redilation Phase of the Post-Illumination Pupil Response (PIPR). | Q36109184 | ||
Full-Field Pupillary Light Responses, Luminance Thresholds, and Light Discomfort Thresholds in CEP290 Leber Congenital Amaurosis Patients | Q36252686 | ||
Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans | Q36448953 | ||
Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutants | Q36709692 | ||
Adaptation to steady light by intrinsically photosensitive retinal ganglion cells | Q36820224 | ||
Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics | Q36937189 | ||
Defining the residual vision in leber congenital amaurosis caused by RPE65 mutations | Q37317693 | ||
The influence of intrinsically-photosensitive retinal ganglion cells on the spectral sensitivity and response dynamics of the human pupillary light reflex. | Q37480948 | ||
Variations in NPHP5 in patients with nonsyndromic leber congenital amaurosis and Senior-Loken syndrome. | Q37635389 | ||
Postretinal Structure and Function in Severe Congenital Photoreceptor Blindness Caused by Mutations in the GUCY2D Gene. | Q37641855 | ||
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Leber congenital amaurosis caused by Lebercilin (LCA5) mutation: retained photoreceptors adjacent to retinal disorganization. | Q39973030 | ||
Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis | Q40523047 | ||
Overlap of abnormal photoreceptor development and progressive degeneration in Leber congenital amaurosis caused by NPHP5 mutation. | Q41643474 | ||
Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells | Q42288630 | ||
Determination of Rod and Cone Influence to the Early and Late Dynamic of the Pupillary Light Response | Q42786166 | ||
Treatment possibilities for retinitis pigmentosa | Q42852876 | ||
Melanopsin is expressed in PACAP-containing retinal ganglion cells of the human retinohypothalamic tract | Q45124600 | ||
Quantifying rod photoreceptor-mediated vision in retinal degenerations: dark-adapted thresholds as outcome measures | Q45238349 | ||
Human retinal disease from AIPL1 gene mutations: foveal cone loss with minimal macular photoreceptors and rod function remaining | Q45862739 | ||
Leber congenital amaurosis caused by an RPGRIP1 mutation shows treatment potential | Q45866090 | ||
Retinal optogenetic therapies: clinical criteria for candidacy | Q45886746 | ||
Photoreceptor degeneration in vitamin A deprivation and retinitis pigmentosa: the equivalent light hypothesis. | Q46607690 | ||
Pupillary correlates of light-evoked melanopsin activity in humans | Q46762339 | ||
Synaptic influences on rat ganglion-cell photoreceptors | Q48164141 | ||
Melanopsin-expressing ganglion cells in human retina: Morphology, distribution, and synaptic connections. | Q48342205 | ||
Defining Outcomes for Clinical Trials of Leber Congenital Amaurosis Caused by GUCY2D Mutations | Q48827784 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | retinal ganglion cell | Q927337 |
photoreceptor protein | Q7187894 | ||
P304 | page(s) | 3215-3224 | |
P577 | publication date | 2017-06-01 | |
P1433 | published in | Investigative Ophthalmology Visual Science | Q6060707 |
P1476 | title | Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells | |
P478 | volume | 58 |
Q54935899 | A Robust Optomotor Assay for Assessing the Efficacy of Optogenetic Tools for Vision Restoration. |
Q90152961 | Leber Congenital Amaurosis (LCA): Potential for Improvement of Vision |
Q54558127 | Sleep in Children with Congenital Malformations of the Central Nervous System. |
Q89844598 | Transient pupillary light reflex in CEP290- or NPHP5-associated Leber congenital amaurosis: Latency as a potential outcome measure of cone function |
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