The role of ion channelopathies in sudden cardiac death: implications for clinical practice

scientific article

The role of ion channelopathies in sudden cardiac death: implications for clinical practice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3109/07853890.2013.783994
P698PubMed publication ID23651009

P2093author name stringChristopher L-H Huang
Claire A Martin
Gareth D K Matthews
P2860cites workMiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmiaQ22009462
Cardiac conduction defects associate with mutations in SCN5AQ22010507
Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillationQ24293547
A cardiac arrhythmia syndrome caused by loss of ankyrin-B functionQ24295030
Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leakQ24296910
A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 geneQ24297875
Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmiasQ24298971
Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channelQ24300840
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humansQ24608179
Epidemiology of sudden cardiac death: clinical and research implicationsQ24650947
Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org)Q24654954
Functional effects of KCNE3 mutation and its role in the development of Brugada syndromeQ24655604
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac deathQ24675134
Determinants of incomplete penetrance and variable expressivity in heritable cardiac arrhythmia syndromesQ27030767
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardiaQ28201561
Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)Q28206505
The genetic basis of Brugada syndrome: a mutation updateQ28252115
Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden deathQ28278262
Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardiaQ28279395
Catecholaminergic polymorphic ventricular tachycardiaQ28287523
The mechanism of catecholaminergic polymorphic ventricular tachycardia may be triggered activity due to delayed afterdepolarizationQ28306389
Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to agingQ28593454
Modelling the long QT syndrome with induced pluripotent stem cellsQ29620092
Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published dataQ31111759
"Brugada" syndrome: clinical data and suggested pathophysiological mechanismQ31913453
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.Q33145274
Autosomal recessive catecholamine- or exercise-induced polymorphic ventricular tachycardia: clinical features and assignment of the disease gene to chromosome 1p13-21.Q33146452
Yield of genetic screening in inherited cardiac channelopathies: how to prioritize access to genetic testing.Q43266239
Paradoxic abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevationQ43858714
Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndromeQ44648714
Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypesQ44723715
Delay in right ventricular activation contributes to Brugada syndromeQ44781964
Gender difference and drug challenge in Brugada syndromeQ44803535
Are women with severely symptomatic brugada syndrome different from men?Q46056314
Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndromeQ46201813
High-density substrate mapping in Brugada syndrome: combined role of conduction and repolarization heterogeneities in arrhythmogenesis.Q46269742
Phenotypic variability and unusual clinical severity of congenital long-QT syndrome in a founder populationQ46301151
Mutation in the KCNQ1 gene leading to the short QT-interval syndromeQ47438291
Compound mutations: a common cause of severe long-QT syndromeQ47857406
Postmortem long QT syndrome genetic testing for sudden unexplained death in the youngQ48480320
Long-term follow-up of patients from a randomised trial of atrial versus ventricular pacing for sick-sinus syndrome.Q50632243
Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction: two-year findings from the Oregon Sudden Unexpected Death Study.Q50778872
Clinical course and risk stratification of patients affected with the Jervell and Lange-Nielsen syndrome.Q51145417
QTc behavior during exercise and genetic testing for the long-QT syndrome.Q51498727
Sudden death in the general population in Okinawa: incidence and causes of death.Q53732503
A complex double deletion in LMNA underlies progressive cardiac conduction disease, atrial arrhythmias, and sudden death.Q54383005
Survivors of Out-of-Hospital Cardiac Arrest With Apparently Normal Heart: Need for Definition and Standardized Clinical EvaluationQ55970441
The prevalence, incidence and prognostic value of the Brugada-type electrocardiogram: a population-based study of four decadesQ33146752
Natural history of Brugada syndrome: insights for risk stratification and managementQ33147491
Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.Q33147854
Body surface area of ST elevation and the presence of late potentials correlate to the inducibility of ventricular tachyarrhythmias in Brugada syndromeQ33148073
Proposed diagnostic criteria for the Brugada syndrome: consensus reportQ33148286
Risk stratification in the long-QT syndrome.Q33148941
Implantable cardioverter defibrillator in high-risk long QT syndrome patientsQ33148945
Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heartQ33148999
Short QT Syndrome: a familial cause of sudden deathQ33149259
Efficacy of quinidine in high-risk patients with Brugada syndromeQ33151791
Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: a molecular autopsy of 49 medical examiner/coroner's casesQ33152066
Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndromeQ33152228
Arrhythmogenic right ventricular dysplasia: a United States experienceQ33153393
Risk stratification of individuals with the Brugada electrocardiogram: a meta-analysisQ33154041
Mouse models of long QT syndromeQ33154363
Outcome after implantation of a cardioverter-defibrillator in patients with Brugada syndrome: a multicenter studyQ33154495
Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardiaQ33155477
Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndromeQ33156201
Repolarization heterogeneity in the right ventricular outflow tract: correlation with ventricular arrhythmias in Brugada patients and in an in vitro canine Brugada modelQ33156240
Sudden cardiac arrest associated with early repolarizationQ33156255
Long-term prognosis of probands with Brugada-pattern ST-elevation in leads V1-V3.Q33157954
Long-term prognosis of patients diagnosed with Brugada syndrome: Results from the FINGER Brugada Syndrome RegistryQ33158291
Idiopathic ventricular fibrillationQ33160592
Risk stratification in Brugada syndrome: results of the PRELUDE (PRogrammed ELectrical stimUlation preDictive valuE) registry.Q33160801
Brugada syndrome 2012.Q33161523
Catecholaminergic polymorphic ventricular tachycardia in children. A 7-year follow-up of 21 patientsQ33173888
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndromeQ33174622
Early repolarizationQ33539317
A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotypeQ33572315
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testingQ33655317
Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevationQ33876613
The syndrome of right bundle branch block ST segment elevation in V1 to V3 and sudden death--the Brugada syndromeQ33935865
Ventricular fibrillation with prominent early repolarization associated with a rare variant of KCNJ8/KATP channelQ34015485
Early repolarization: electrocardiographic phenotypes associated with favorable long-term outcomeQ34027142
Genetics of sudden cardiac deathQ34203505
Sudden death associated with short-QT syndrome linked to mutations in HERG.Q34283788
Short QT syndrome: pharmacological treatmentQ34314532
Cellular basis for the electrocardiographic J waveQ34370136
Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.Q34385271
Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.Q34395488
Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registryQ34422572
Arrhythmogenic marker for the sudden unexplained death syndrome in Thai men.Q34444862
Out-of-hospital cardiac arrest in the 1990's: a population-based study in the Maastricht area on incidence, characteristics and survivalQ34445532
Brugada syndrome: from cell to bedsideQ34667046
Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutationQ34785746
Mapping of reentrant spontaneous polymorphic ventricular tachycardia in a Scn5a+/- mouse modelQ34979810
Estradiol promotes sudden cardiac death in transgenic long QT type 2 rabbits while progesterone is protectiveQ35427930
Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardiaQ36037969
Reduced Na(+) and higher K(+) channel expression and function contribute to right ventricular origin of arrhythmias in Scn5a+/- miceQ36079245
Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromesQ36140857
The congenital long QT syndromes from genotype to phenotype: clinical implicationsQ36335249
Cardiac channel molecular autopsy: insights from 173 consecutive cases of autopsy-negative sudden unexplained death referred for postmortem genetic testing.Q36399631
The role of molecular autopsy in unexplained sudden cardiac deathQ36443125
From pulsus to pulseless: the saga of cardiac alternansQ36489923
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cellsQ37005193
Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillationQ37156064
Prevalence of the congenital long-QT syndrome.Q37442080
Early repolarization syndrome – a new electrical disorder associated with sudden cardiac death –.Q37788474
Cardiac ion channel mutations in the sudden infant death syndromeQ37826837
Genetics of ion-channel disorders.Q37997324
Brugada electrocardiographic pattern induced by feverQ37997443
Ryanodine receptor physiology and its role in diseaseQ37997675
Electrocardiographic characteristics and SCN5A mutations in idiopathic ventricular fibrillation associated with early repolarizationQ39452561
Trafficking defects and gating abnormalities of a novel SCN5A mutation question gene-specific therapy in long QT syndrome type 3.Q39722604
Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse modelQ39814350
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.Q40355175
Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ currentQ41256047
Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain.Q41858723
Distribution, splicing and glucocorticoid-induced expression of cardiac alpha 1C and alpha 1D voltage-gated Ca2+ channel mRNAsQ42448384
KCNH2-K897T is a genetic modifier of latent congenital long-QT syndromeQ42665516
Regional variations in action potential alternans in isolated murine Scn5a (+/-) hearts during dynamic pacingQ43102967
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)364-374
P577publication date2013-05-08
P1433published inAnnals of MedicineQ4767853
P1476titleThe role of ion channelopathies in sudden cardiac death: implications for clinical practice
P478volume45

Reverse relations

cites work (P2860)
Q26777170Genetics of channelopathies associated with sudden cardiac death
Q39038606Murine Electrophysiological Models of Cardiac Arrhythmogenesis

Search more.