Oxazolidinone antibiotics.

scientific article

Oxazolidinone antibiotics. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(01)06964-1
P8608Fatcat IDrelease_inqg6xlqevcdzdredho45atadm
P698PubMed publication ID11747939

P50authorRonald N JonesQ120908182
Daniel J. DiekemaQ43292463
P2860cites workThe oxazolidinone linezolid inhibits initiation of protein synthesis in bacteriaQ24519053
Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721Q24676621
Oxazolidinones, a new class of synthetic antituberculosis agent in vitro and in vivo activities of DuP-721 against Mycobacterium tuberculosisQ28325680
Linezolid therapy of vancomycin-resistant Enterococcus faecium experimental endocarditisQ28346136
Oxazolidinones: a reviewQ28373208
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agentsQ28379204
Bacterial pathogens isolated from patients with bloodstream infection: frequencies of occurrence and antimicrobial susceptibility patterns from the SENTRY antimicrobial surveillance program (United States and Canada, 1997).Q30453672
Nasal carriage as a source of Staphylococcus aureus bacteremia. Study GroupQ31797996
Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter studyQ31918107
Efficacy of linezolid in a staphylococcal endocarditis rabbit modelQ32061964
Successful treatment of vancomycin-resistant Enterococcus endocarditis with oral linezolidQ33942509
Linezolid, a novel oxazolidinone antibiotic: assessment of monoamine oxidase inhibition using pressor response to oral tyramineQ43613495
Linezolid for the treatment of community-acquired pneumonia in hospitalized children. Linezolid Pediatric Pneumonia Study GroupQ43613993
Linezolid breakpointsQ43650735
Linezolid resistance in a clinical isolate of Staphylococcus aureusQ43690311
Susceptibility testing with linezolid by different methods, in relation to published 'general breakpoints'.Q43726465
Successful treatment of disseminated Mycobacterium chelonae infection with linezolidQ43732842
Emergence of vancomycin resistance in coagulase-negative staphylococciQ44441075
Effect of quinupristin/dalfopristin on the outcome of vancomycin-resistant Enterococcus faecium bacteraemia: comparison with a control cohortQ44918473
Successful treatment of persistent vancomycin-resistant Enterococcus faecium bacteremia with linezolid and gentamicinQ45206563
Activity of linezolid against Gram-positive cocci possessing genes conferring resistance to protein synthesis inhibitorsQ45722453
Successful treatment of vertebral osteomyelitis with linezolid in a patient receiving hemodialysis and with persistent methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus bacteremias.Q54043070
Successful treatment of vancomycin-resistant Enterococcus faecium bacteremia with linezolid after failure of treatment with synercid (quinupristin/dalfopristin).Q54062867
Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant gram-positive bacterial infections.Q54066894
Methicillin-resistant Staphylococcus aureus infection in a renal allograft recipient treated successfully with a novel new antimicrobial agent (linezolid): new treatment options for infections due to resistant organisms.Q54075012
Comparative in vitro and bactericidal activity of oxazolidinone antibiotics against multidrug-resistant enterococciQ74468119
In vitro antibiotic synergy against Flavobacterium meningosepticum: implications for therapeutic optionsQ74578381
Vancomycin-resistant enterococciQ74578393
A novel antimicrobial agent joins the battle against resistant bacteriaQ74587568
Prevalence of antimicrobial resistance among respiratory tract isolates of Streptococcus pneumoniae in North America: 1997 results from the SENTRY antimicrobial surveillance programQ77496292
In vitro activity of linezolid and eperezolid against anaerobic bacteriaQ77664314
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to the novel oxazolidinones eperezolid (PNU-100592) and linezolid (PNU-100766)Q78093828
In vitro activity of linezolid and eperezolid, two novel oxazolidinone antimicrobial agents, against anaerobic bacteriaQ80057159
In vitro activities of linezolid against important gram-positive bacterial pathogens including vancomycin-resistant enterococciQ33977497
In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against Staphylococci and Enterococci, including vancomycin- intermediate and -resistant strainsQ33979251
MICs of oxazolidinones for Rhodococcus equi strains isolated from humans and animalsQ33979553
Comparative in vitro activities of linezolid, quinupristin-dalfopristin, moxifloxacin, and trovafloxacin against erythromycin-susceptible and -resistant streptococciQ33979988
Randomized comparison of linezolid (PNU-100766) versus oxacillin-dicloxacillin for treatment of complicated skin and soft tissue infectionsQ33981016
Activities of linezolid against rapidly growing mycobacteriaQ33981613
Efficacy of linezolid in treatment of experimental endocarditis caused by methicillin-resistant Staphylococcus aureusQ33982746
Emerging therapies for serious gram-positive bacterial infections: a focus on linezolidQ34052631
Vancomycin-resistant Enterococcus faecium meningitis successfully managed with linezolid: case report and review of the literatureQ34312876
Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci.Q35122591
In vitro antimicrobial activities and spectra of U-100592 and U-100766, two novel fluorinated oxazolidinonesQ35123200
In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis.Q35123415
In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections.Q35125132
In vitro activities in new oxazolidinone antimicrobial agents against enterococciQ35125827
In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfopristin-quinupristin against Staphylococcus aureus and Staphylococcus epidermidisQ35128574
In vitro activities of the oxazolidinone antibiotics U-100592 and U-100766 against Staphylococcus aureus and coagulase-negative Staphylococcus speciesQ35132865
In vitro activity and spectrum of LY333328, a novel glycopeptide derivative.Q35133106
Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactionsQ35138447
In vitro activities of an investigational quinolone, glycylcycline, glycopeptide, streptogramin, and oxazolidinone tested alone and in combinations against vancomycin-resistant Enterococcus faeciumQ35139128
Mechanism of action of DuP 721: inhibition of an early event during initiation of protein synthesisQ35318121
Emerging multiply resistant enterococci among clinical isolates. I. Prevalence data from 97 medical center surveillance study in the United States. Enterococcus Study GroupQ36688995
Daptomycin disrupts membrane potential in growing Staphylococcus aureusQ36756893
Efficacy of linezolid in experimental otitis mediaQ39473141
In vitro activities of linezolid alone and in combination with amoxicillin, clarithromycin, and metronidazole against Helicobacter pyloriQ39474501
In vitro activities of linezolid against multiple Nocardia speciesQ39477004
Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilQ39478313
Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assayQ39557542
The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycinQ39785029
Bacteremia due to viridans streptococci in neutropenic patients: a reviewQ40707109
Oxazolidinones: new antibacterial agentsQ41478614
New approaches to reduce Staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriageQ41707274
Activity and mechanism of action of DuP 105 and DuP 721, new oxazolidinone compoundsQ42214936
In-vitro activity of oxazolidinones against Mycobacterium avium ComplexQ42276718
Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activityQ42557282
Comparison of length of hospital stay for patients with known or suspected methicillin-resistant Staphylococcus species infections treated with linezolid or vancomycin: a randomized, multicenter trialQ43546278
Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolidQ43588787
P433issue9297
P407language of work or nameEnglishQ1860
P921main subjectantibioticQ12187
P304page(s)1975-1982
P577publication date2001-12-01
P1433published inThe LancetQ939416
P1476titleOxazolidinone antibiotics
P478volume358

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cites work (P2860)
Q90929349A genetics-free method for high-throughput discovery of cryptic microbial metabolites
Q34563237A guide to antibiotics for the interventional radiologist
Q41881947A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr.
Q24681027Activity of linezolid against 3,251 strains of uncommonly isolated gram-positive organisms: report from the SENTRY Antimicrobial Surveillance Program
Q39895301Activity of linezolid in an in vitro pharmacokinetic-pharmacodynamic model using different dosages and Staphylococcus aureus and Enterococcus faecalis strains with and without a hypermutator phenotype
Q33185287Age-related trends in pathogen frequency and antimicrobial susceptibility of bloodstream isolates in North America: SENTRY Antimicrobial Surveillance Program, 1997-2000.
Q28075453Alternative pre-approved and novel therapies for the treatment of anthrax
Q46013312An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates.
Q36233502Anti-MRSA agents: under investigation, in the exploratory phase and clinically available
Q36283731Antibiotic resistance in Staphylococcus aureus and its relevance in therapy
Q35627661Antibiotic treatment of multidrug-resistant organisms in cystic fibrosis
Q34156349Antibiotics and bacterial resistance in the 21st century
Q27025271Antibiotics that target protein synthesis
Q41919747Antimicrobial activity of allylic thiocyanates derived from the Morita-Baylis-Hillman reaction
Q42846946Aqueous and Vitreous Penetration of Linezolid and Levofloxacin After Oral Administration
Q56969305Catalytic Oxidative Carbonylation of Amino Moieties to Ureas, Oxamides, 2-Oxazolidinones, and Benzoxazolones
Q43595562Catalytic synthesis of hydroxymethyl-2-oxazolidinones from glycerol or glycerol carbonate and urea
Q47611899Clinical Pharmacokinetics and Pharmacodynamics of Oxazolidinones
Q46548640Clinical experience with linezolid for the treatment of central nervous system infections
Q44285699Clinical experience with linezolid for the treatment of nocardia infection
Q26750683Combating Tuberculosis Infection: A Forbidding Challenge
Q40067743Current therapies for the treatment of multidrug-resistant tuberculosis in children in India
Q48951110Decoding the cryptic genomes of fungi: the promise of novel antibiotics
Q44306333Determination of disk diffusion and MIC quality control parameters for AZD2563, a novel long-acting oxazolidinone
Q59296697Direct Assembly of 2-Oxazolidinones by Chemical Fixation of Carbon Dioxide
Q53739563Discovery of Fluorine-Containing Benzoxazinyl-oxazolidinones for the Treatment of Multidrug Resistant Tuberculosis.
Q38777085Drug monitoring and individual dose optimization of antimicrobial drugs: oxazolidinones
Q26766204Drug-Induced Metabolic Acidosis
Q35683967Drug-resistant tuberculosis: emerging treatment options
Q36172366Effect of linezolid on the 50% lethal dose and 50% protective dose in treatment of infections by Gram-negative pathogens in naive and immunosuppressed mice and on the efficacy of ciprofloxacin in an acute murine model of septicemia
Q35826505Effect of oral linezolid on the pressor response to intravenous tyramine
Q44895305Effects of protein-calorie malnutrition on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats
Q87624258Efficacy and safety of linezolid for the treatment of infections in children: a meta-analysis
Q33412664Efficacy and safety of linezolid in treating gram-positive bacterial infection in the elderly: a retrospective study
Q33412202Efficacy of linezolid on gram-positive bacterial infection in elderly patients and the risk factors associated with thrombocytopenia.
Q37875564Eight-year (2002-2009) summary of the linezolid (Zyvox® Annual Appraisal of Potency and Spectrum; ZAAPS) program in European countries
Q34756483Emerging resistance to antibiotics against respiratory bacteria: impact on therapy of community-acquired pneumonia in children
Q44516868Failure of intravenous linezolid to treat Clostridium difficile associated diarrhea
Q36702968First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States
Q37757660Global tuberculosis drug development pipeline: the need and the reality.
Q24542412Good clinical outcomes but high rates of adverse reactions during linezolid therapy for serious infections: a proposed protocol for monitoring therapy in complex patients
Q44572563High-performance liquid chromatographic analysis of DA-7867, a new oxazolidinone, in human plasma and urine and in rat tissue homogenates
Q43251091Improved antimicrobial activity of linezolid against vancomycin-intermediate Staphylococcus aureus
Q50855186In Vitro Activities of LCB 01-0648, a Novel Oxazolidinone, against Gram-Positive Bacteria.
Q49552573In Vivo Activity of LCB 01-0699, a Prodrug of LCB 01-0648, against Staphylococcus aureus
Q42112190In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea
Q40410703In vitro activities of DA-7867, a novel oxazolidinone, against recent clinical isolates of aerobic and anaerobic bacteria
Q35006670In vitro activities of the novel cephalosporin LB 11058 against multidrug-resistant Staphylococci and Streptococci
Q42123065In vitro activities of tigecycline and eight other antimicrobials against different Nocardia species identified by molecular methods
Q44084920In vitro activity of linezolid, quinupristin-dalfopristin, vancomycin, teicoplanin, moxifloxacin and mupirocin against methicillin-resistant Staphylococcus aureus: comparative evaluation by the E test and a broth microdilution method
Q39792579In vitro and in vivo activities of novel 2-(thiazol-2-ylthio)-1beta-methylcarbapenems with potent activities against multiresistant gram-positive bacteria
Q30227297Intervention strategies for an influenza pandemic taking into account secondary bacterial infections
Q38053000Is repositioning of drugs a viable alternative in the treatment of tuberculosis?
Q35139437LEADER Program results for 2009: an activity and spectrum analysis of linezolid using 6,414 clinical isolates from 56 medical centers in the United States
Q36730155Linezolid Surveillance Results for the United States (LEADER Surveillance Program 2014).
Q37663491Linezolid compared with vancomycin for the prevention of methicillin-resistant Staphylococcus aureus or Staphylococcus epidermidis vascular graft infection in rats: A randomized, controlled, experimental study
Q38175628Linezolid for the treatment of drug-resistant tuberculosis in children: a review and recommendations.
Q38929509Linezolid in the treatment of drug-resistant tuberculosis: the challenge of its narrow therapeutic index
Q43130393Linezolid penetration into cerebrospinal fluid and brain tissue
Q44479766Linezolid-induced anemia
Q57057570Linezolid-induced pure red cell aplasia: a case report and literature review
Q36724345Linezolid: a new antibiotic for newborns and children?
Q39044932Linezolid: a promising option in the treatment of Gram-positives.
Q47577709Long-lasting successful dissemination of resistance to oxazolidinones in MDR Staphylococcus epidermidis clinical isolates in a tertiary care hospital in France
Q37071990Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr
Q37072346Multidrug- and extensively drug-resistant tuberculosis, Germany
Q92325220Multidrug-resistant tuberculosis infection and disease in children: a review of new and repurposed drugs
Q35673808New developments in antibacterial choice for lower respiratory tract infections in elderly patients
Q37996998New drugs for the treatment of tuberculosis: needs, challenges, promise, and prospects for the future
Q36237707Nosocomial bacterial infections in Intensive Care Units. I: Organisms and mechanisms of antibiotic resistance
Q35073345Novel antibacterial agents for the treatment of serious Gram-positive infections
Q44455151Occurrence of MRSA endocarditis during linezolid treatment
Q35637071Oritavancin and tigecycline: investigational antimicrobials for multidrug-resistant bacteria
Q40565401Oxazolidinones and glycopeptides
Q64218681Palladium-Catalyzed Carboxy-Alkynylation of Propargylic Amines Using Carbonate Salts as Carbon Dioxide Source
Q46845906Pharmacoeconomic evaluation of linezolid versus teicoplanin in bacteremia by Gram-positive microorganisms
Q35785222Pharmacogenomic strategies against resistance development in microbial infections
Q58854622Pharmacokinetics of DA-7218, a new oxazolidinone, and its active metabolite, DA-7157, after intravenous and oral administration of DA-7218 and DA-7157 to rats
Q35546926Pharmacokinetics of DA-7867, a new oxazolidinone, after intravenous or oral administration to rats: intestinal first-pass effect
Q64080142Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies
Q34837338Quorum sensing: an emerging target for antibacterial chemotherapy?
Q64131294Recomendaciones GEIPC-SEIMC y GTEI-SEMICYUC para el tratamiento antibiótico de infecciones por cocos grampositivos en el paciente crítico
Q38353565Safety and tolerability profile of second-line anti-tuberculosis medications
Q37736231Selective in vivo and in vitro activities of 3,3'-4-nitrobenzylidene-bis-4-hydroxycoumarin against methicillin-resistant Staphylococcus aureus by inhibition of DNA polymerase III.
Q35215457Serum and cerebrospinal fluid concentrations of linezolid in neurosurgical patients.
Q83079095Spread of cfr gene among staphylococci conferring resistance to linezolid in a patient under treatment
Q42795664Stability of linezolid activity in an era of mobile oxazolidinone resistance determinants: results from the 2009 Zyvox® Annual Appraisal of Potency and Spectrum program
Q36894458Staphylococci.
Q44859922Successful medical treatment of multiple brain abscesses due to Nocardia farcinica in a paediatric renal transplant recipient.
Q44877259Successful treatment of disseminated cerebritis complicating methicillin-resistant Staphylococcus aureus Endocarditis unresponsive to vancomycin therapy with linezolid.
Q36933217Surgical site infection prophylaxis strategies for cardiothoracic surgery: a decision-analytic model
Q64942397Synthesis and Biological Evaluation of Pyrimidine-oxazolidin-2-arylimino Hybrid Molecules as Antibacterial Agents.
Q44239645Synthesis and antibacterial activity of 5-substituted oxazolidinones
Q37268425Synthesis and antibacterial activity of novel curcumin derivatives containing heterocyclic moiety
Q46381177Synthesis of some heterofunctionalized penicillanic acid derivatives and investigation of their biological activities
Q80362477The Advantage of Bactericidal Drugs in the Treatment of Infection
Q44437069Tooth discoloration after treatment with linezolid
Q36758570Treatment of Staphylococcus aureus infections: new issues, emerging therapies and future directions
Q36688930Use of linezolid in children: an overview of recent advances
Q41655310Validation of a commercial dry-form broth microdilution device (Sensititre) for testing tedizolid, a new oxazolidinone
Q42285540ZAAPS Program results for 2010: an activity and spectrum analysis of linezolid using clinical isolates from 75 medical centres in 24 countries

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