Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding

scientific article

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M507000200
P698PubMed publication ID16234249

P50authorSakae TanakaQ39065998
P2093author name stringAkira Fukuda
Kozo Nakamura
Hiromi Oda
Hirotaka Chikuda
Tsuyoshi Miyazaki
Yuho Kadono
Hisataka Yasuda
Atsuhiko Hikita
Hidetoshi Wakeyama
P2860cites workEvidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1Q24305944
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1Q24307304
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cellsQ24315251
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cellsQ28119154
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survivalQ28142897
Catalytic properties of ADAM19Q28189426
The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptorQ28285539
A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNFQ28296638
Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossificationQ28505336
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of RasQ28646214
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclastsQ29618116
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
EGF receptor ligandsQ34185050
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicityQ36400613
Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosisQ39124107
Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascadesQ41708821
Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertaseQ43559838
Osteoprotegerin Regulates Bone Formation through a Coupling Mechanism with Bone ResorptionQ44590734
P433issue50
P407language of work or nameEnglishQ1860
P304page(s)41700-41706
P577publication date2005-10-18
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding
P478volume280

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cites work (P2860)
Q24599024A comprehensive manually curated reaction map of RANKL/RANK-signaling pathway
Q37873719Bone metastasis in prostate cancer: emerging therapeutic strategies.
Q39797126Involvement of a disintegrin and metalloproteinase 10 and 17 in shedding of tumor necrosis factor-alpha
Q37199218RANK, RANKL and osteoprotegerin in bone biology and disease.
Q40252425Regulation of cementoblast function by P. gingivalis lipopolysaccharide via TLR2.
Q38183261Regulatory mechanisms of RANKL presentation to osteoclast precursors
Q33958982Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.
Q36891815Signaling axis in osteoclast biology and therapeutic targeting in the RANKL/RANK/OPG system
Q61135621Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss
Q41927546Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction