Biochemical, pharmacological and structural characterization of a new PLA2 from Crotalus durissus terrificus (South American rattlesnake) venom

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Biochemical, pharmacological and structural characterization of a new PLA2 from Crotalus durissus terrificus (South American rattlesnake) venom is …
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scholarly articleQ13442814

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P356DOI10.1007/S10930-005-6718-Z
P698PubMed publication ID16283546

P50authorLéa Rodrigues-SimioniQ111488679
Sergio MarangoniQ114405113
P2093author name stringMarcos Hikari Toyama
Stephen Hyslop
Daniela Oliveira Toyama
Saraguaci Hernandez-Oliveira
P2860cites workIsolation of a crotoxin-like protein from the venom of a South American rattlesnake (Crotalus durissus collilineatus)Q70265611
Comparison of crotoxin isoforms reveals that stability of the complex plays a major role in its pharmacological actionQ70767086
An aqueous endpoint assay of snake venom phospholipase A2Q71807161
Enzymatic characterization of a novel phospholipase A2 from Crotalus durissus cascavella rattlesnake (Maracambóia) venomQ73573981
Amino acid sequence of piratoxin-II, a myotoxic lys49 phospholipase A(2) homologue from Bothrops pirajai venomQ73915123
Isolation and preliminary enzymatic characterization of a novel PLA2 from Crotalus durissus collilineatus venomQ74128706
Amino acid sequence of piratoxin-I, a myotoxin from Bothrops pirajai snake venom, and its biological activity after alkylation with p-bromophenacyl bromideQ77684256
Diversity of group types, regulation, and function of phospholipase A2Q28252971
Structural and functional characterization of basic PLA2 isolated from Crotalus durissus terrificus venom.Q31058316
Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymesQ33339804
Receptors for a growing family of secreted phospholipases A2.Q33633078
Phospholipase A2 myotoxins from Bothrops snake venomsQ34391390
Group IV cytosolic phospholipase A2 (PLA2) function: insights from the knockout mouse.Q35094325
Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological propertiesQ35690564
An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic actionQ35690573
Skeletal muscle degeneration induced by venom phospholipases A2: insights into the mechanisms of local and systemic myotoxicityQ35690578
The origin of the diversity of crotoxin isoforms in the venom of Crotalus durissus terrificusQ36734540
cDNA cloning and sequence analysis of a lysine-49 phospholipase A2 myotoxin from Agkistrodon contortrix laticinctus snake venomQ36792965
Biological roles of the two components of crotoxinQ37481219
Crotoxin, half-century of investigations on a phospholipase A2 neurotoxinQ38333828
A model to explain the pharmacological effects of snake venom phospholipases A2.Q38664430
Mini-review. The crotoxin complex--an example of biochemical and pharmacological protein complementationQ40115907
New insights on mammalian phospholipase A2(s); comparison of arachidonoyl-selective and -nonselective enzymes.Q40879811
Structure and function relationship of crotoxin, a heterodimeric neurotoxic phospholipase A2 from the venom of a South-American rattlesnakeQ41049281
Observations on the isolated phrenic nerve diaphragm preparation of the rat.Q42128518
The isolated chick biventer cervicis nerve-muscle preparationQ42149154
Structural, enzymatic and biological properties of new PLA(2) isoform from Crotalus durissus terrificus venomQ44522226
Neurotoxic and myotoxic actions of crotoxin-like and Crotalus durissus cascavella whole venom in the chick biventer cervicis preparationQ44806760
A comparative study of biological activities of crotoxin and CB fraction of venoms from Crotalus durissus terrificus, Crotalus durissus cascavella and Crotalus durissus collilineatusQ45000319
Anti-sera raised in rabbits against crotoxin and phospholipase A2 from Crotalus durissus cascavella venom neutralize the neurotoxicity of the venom and crotoxinQ47217379
Multiplicity of acidic subunit isoforms of crotoxin, the phospholipase A2 neurotoxin from Crotalus durissus terrificus venom, results from posttranslational modificationsQ67939209
Crotoxin, a phospholipase A2 neurotoxin from the South American rattlesnake Crotalus durissus terrificus: purification of several isoforms and comparison of their molecular structure and of their biological activitiesQ68284311
Several isoforms of crotoxin are present in individual venoms from the South American rattlesnake Crotalus durissus terrificusQ69005240
P433issue4
P921main subjectsnake venomQ424200
Crotalus durissusQ854864
Crotalus durissus terrificusQ16553787
P304page(s)233-242
P577publication date2005-05-01
P1433published inThe Protein JournalQ15760422
P1476titleBiochemical, pharmacological and structural characterization of a new PLA2 from Crotalus durissus terrificus (South American rattlesnake) venom
P478volume24