| scholarly article | Q13442814 |
| P356 | DOI | 10.1021/BI052015L |
| P8608 | Fatcat ID | release_kz3rde4xzveb3bdoqkfvv5f6nm |
| P932 | PMC publication ID | 2519118 |
| P698 | PubMed publication ID | 16388584 |
| P5875 | ResearchGate publication ID | 7382005 |
| P2093 | author name string | John M Denu | |
| Adam L Garske | |||
| P2860 | cites work | Sirtuins: Sir2-related NAD-dependent protein deacetylases | Q21092883 |
| Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity | Q22010164 | ||
| hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase | Q24291829 | ||
| Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase | Q24293656 | ||
| Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation | Q24293737 | ||
| The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase | Q24296836 | ||
| Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence | Q24297146 | ||
| Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state | Q24312132 | ||
| SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1 | Q24337470 | ||
| FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1) | Q24338668 | ||
| Gapped BLAST and PSI-BLAST: a new generation of protein database search programs | Q24545170 | ||
| Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription | Q24545711 | ||
| DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53 | Q24555770 | ||
| SIRT1 regulates HIV transcription via Tat deacetylation | Q24797263 | ||
| Structure of a Sir2 enzyme bound to an acetylated p53 peptide | Q27639892 | ||
| Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide | Q27642500 | ||
| Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase | Q27860668 | ||
| The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability | Q27937288 | ||
| Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins | Q28139564 | ||
| A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60 | Q28205099 | ||
| Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 | Q28237795 | ||
| Mechanism of human SIRT1 activation by resveratrol | Q28238262 | ||
| The Sir2 family of protein deacetylases | Q28266179 | ||
| The Werner syndrome protein at the crossroads of DNA repair and apoptosis | Q28279631 | ||
| Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions | Q28609621 | ||
| Histone modifications in transcriptional regulation | Q29614770 | ||
| Use of an oriented peptide library to determine the optimal substrates of protein kinases | Q29614792 | ||
| Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine | Q30876890 | ||
| Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds | Q31063489 | ||
| Determination of substrate specificity for peptide deformylase through the screening of a combinatorial peptide library | Q31934195 | ||
| Quantum dots as a visual aid for screening bead-bound combinatorial libraries | Q33194959 | ||
| SIRT1 shows no substrate specificity in vitro | Q33210693 | ||
| Bioactive peptides from libraries. | Q33214377 | ||
| The Sir 2 family of protein deacetylases | Q33222287 | ||
| Visualization of SHP-1-target interaction. | Q34354348 | ||
| Lighting up cells with quantum dots | Q35076084 | ||
| Ageing and PARP. | Q36136112 | ||
| The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. | Q40564766 | ||
| DNA damage-induced translocation of the Werner helicase is regulated by acetylation | Q40696914 | ||
| Mutational analysis of the guanylyltransferase component of Mammalian mRNA capping enzyme | Q42603122 | ||
| Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases | Q43917517 | ||
| A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis | Q44073439 | ||
| Mechanism of Nicotinamide Inhibition and Transglycosidation by Sir2 Histone/Protein Deacetylases | Q44605209 | ||
| Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases | Q44993659 | ||
| General method for rapid synthesis of multicomponent peptide mixtures | Q45101169 | ||
| A new type of synthetic peptide library for identifying ligand-binding activity | Q45106336 | ||
| Unstructured conformations are a substrate requirement for the Sir2 family of NAD-dependent protein deacetylases | Q46677490 | ||
| Combinatorial technologies involving reiterative division/coupling/recombination: statistical considerations. | Q52371262 | ||
| Quantum dot bioconjugates for ultrasensitive nonisotopic detection. | Q54135557 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | quantum dot | Q1133068 |
| P304 | page(s) | 94-101 | |
| P577 | publication date | 2006-01-01 | |
| P1433 | published in | Biochemistry | Q764876 |
| P1476 | title | SIRT1 top 40 hits: use of one-bead, one-compound acetyl-peptide libraries and quantum dots to probe deacetylase specificity | |
| P478 | volume | 45 |
| Q51509279 | A Selective Cyclic Peptidic Human SIRT5 Inhibitor. |
| Q33350596 | A combinatorial H4 tail library for exploring the histone code |
| Q24314096 | A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex |
| Q30975800 | Accurate MALDI-TOF/TOF sequencing of one-bead-one-compound peptide libraries with application to the identification of multiligand protein affinity agents using in situ click chemistry screening |
| Q30317729 | An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms |
| Q24633830 | Biochemical effects of SIRT1 activators |
| Q47140588 | Characterization of CobB kinetics and inhibition by nicotinamide. |
| Q41837725 | Combining mass spectrometry and peptide arrays to profile the specificities of histone deacetylases. |
| Q33870679 | Identifying Human SIRT1 Substrates by Integrating Heterogeneous Information from Various Sources. |
| Q39844388 | Jamming up the "β-staple": regulation of SIRT1 activity by its C-terminal regulatory segment (CTR). |
| Q33940382 | Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy |
| Q38175079 | New assays and approaches for discovery and design of Sirtuin modulators |
| Q34167204 | Process automation toward ultra-high-throughput screening of combinatorial one-bead-one-compound (OBOC) peptide libraries |
| Q35006665 | Profiling deacetylase activities in cell lysates with peptide arrays and SAMDI mass spectrometry |
| Q37809836 | SIRT1 Modulation as a Novel Approach to the Treatment of Diseases of Aging |
| Q47245579 | Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain |
| Q34453795 | Sirtuin catalysis and regulation |
| Q61447859 | Sirtuins in B lymphocytes metabolism and function |
| Q35661567 | Sirtuins in neurodegenerative diseases: a biological-chemical perspective |
| Q33713479 | Solid-phase synthesis and screening of N-acylated polyamine (NAPA) combinatorial libraries for protein binding |
| Q26823308 | Structural basis for sirtuin activity and inhibition |
| Q34027182 | Structure-based development of novel sirtuin inhibitors |
| Q43187910 | Substituting N(epsilon)-thioacetyl-lysine for N(epsilon)-acetyl-lysine in peptide substrates as a general approach to inhibiting human NAD(+)-dependent protein deacetylases |
| Q41976986 | The activity of HDAC8 depends on local and distal sequences of its peptide substrates |
| Q35190517 | The identification of high-affinity G protein-coupled receptor ligands from large combinatorial libraries using multicolor quantum dot-labeled cell-based screening |
| Q33263225 | Two-step fluorescence screening of CD21-binding peptides with one-bead one-compound library and investigation of binding properties of N-(2-hydroxypropyl)methacrylamide copolymer-peptide conjugates |
| Q36631005 | Understanding and exploiting substrate recognition by protein kinases |
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