Single molecule mechanical probing of the SNARE protein interactions

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Single molecule mechanical probing of the SNARE protein interactions is …
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scholarly articleQ13442814

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P356DOI10.1529/BIOPHYSJ.105.073312
P932PMC publication ID1483094
P698PubMed publication ID16648158
P5875ResearchGate publication ID7133494

P50authorVladimir ParpuraQ48808732
Edwin ChapmanQ59541853
P2093author name stringW Liu
Vladimir Parpura
Jihong Bai
Vedrana Montana
U Mohideen
P2860cites workBinding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapsesQ24671842
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assemblyQ26269962
Interactions within the yeast t-SNARE Sso1p that control SNARE complex assemblyQ27627311
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolutionQ27765619
Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae.Q27936151
SNAP receptors implicated in vesicle targeting and fusionQ28131653
A stable interaction between syntaxin 1a and synaptobrevin 2 mediated by their transmembrane domainsQ28140142
Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical propertiesQ28144385
SNARE function analyzed in synaptobrevin/VAMP knockout miceQ28203549
A post-docking role for synaptobrevin in synaptic vesicle fusionQ28243803
Entropic elasticity of lambda-phage DNAQ28247727
Protein-protein interactions contributing to the specificity of intracellular vesicular traffickingQ28249692
Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopyQ28581498
Structural organization of the synaptic exocytosis core complexQ46275944
Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants.Q47069532
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.Q47874870
Tetanus and botulinum neurotoxins are zinc proteases specific for components of the neuroexocytosis apparatusQ48157782
Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevinQ48268335
A marker of early amacrine cell development in rat retinaQ48483977
Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminalsQ48560522
Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects.Q52210225
Expression of synaptobrevin II, cellubrevin and syntaxin but not SNAP-25 in cultured astrocytesQ57979052
Real-time measurement of transmitter release from single synaptic vesiclesQ57979058
Vesicular restriction of synaptobrevin suggests a role for calcium in membrane fusionQ58979943
SNAP-25 and Synaptotagmin 1 Function in Ca2+-Dependent Reversible Docking of Granules to the Plasma MembraneQ60183607
Stable SNARE complex prior to evoked synaptic vesicle fusion revealed by fluorescence resonance energy transferQ64380360
Insulin-induced rapid decrease of a major protein in fat cell plasma membranesQ70498235
Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranesQ73203897
Transport, capture and exocytosis of single synaptic vesicles at active zonesQ74265534
Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosisQ28591459
Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zincQ28609178
Membrane fusion machinery: insights from synaptic proteinsQ28609209
Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevinQ29619130
Single molecule observation of liposome-bilayer fusion thermally induced by soluble N-ethyl maleimide sensitive-factor attachment protein receptors (SNAREs)Q30476464
SNARE-driven, 25-millisecond vesicle fusion in vitroQ30476779
Botulinum toxin type B micromechanosensorQ30501213
Stepwise unfolding of titin under force-clamp atomic force microscopy.Q30658423
How Strong Is the Coordination Bond between a Histidine Tag and Ni - Nitrilotriacetate? An Experiment of Mechanochemistry on Single MoleculesQ30834927
Interactions between synaptic vesicle fusion proteins explored by atomic force microscopyQ30960921
Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurationsQ31031114
Dynamic strength of molecular adhesion bondsQ33915225
The t-SNARE syntaxin is sufficient for spontaneous fusion of synaptic vesicles to planar membranesQ33924441
How does calcium trigger neurotransmitter release?Q33950706
Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viabilityQ34161948
Strength of a weak bond connecting flexible polymer chainsQ34170403
Electrostatic interactions between the syntaxin membrane anchor and neurotransmitter passing through the fusion poreQ34189535
Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junctionQ34207383
Probing the relation between force--lifetime--and chemistry in single molecular bondsQ34243206
Botulinum neurotoxins are zinc proteinsQ34260095
Measurements of vesicle recycling in central neuronsQ34272558
Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis.Q34305380
Identifying kinetic barriers to mechanical unfolding of the T. thermophila ribozymeQ34775534
Mechanisms of glutamate release from astrocytes: gap junction "hemichannels", purinergic receptors and exocytotic release.Q35774444
Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretionQ36641718
Direct measurement of the forces between complementary strands of DNA.Q36728149
Adhesion forces between individual ligand-receptor pairsQ36746851
Determinants of liposome fusion mediated by synaptic SNARE proteinsQ36852539
Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation ratesQ37392835
Molecular mechanisms of clostridial neurotoxinsQ40642444
Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.Q40805470
Syntaxin and synaptobrevin function downstream of vesicle docking in DrosophilaQ41666993
Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-synaptobrevin.Q41712786
Vesicular glutamate transporter-dependent glutamate release from astrocytes.Q44804042
Subunit interface residues of glutathione S-transferase A1-1 that are important in the monomer-dimer equilibriumQ44808493
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs.Q44814891
Syntaxin 1A drives fusion of large dense-core neurosecretory granules into a planar lipid bilayerQ45061933
A functional role for GTP-binding proteins in synaptic vesicle cycling.Q45988564
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages15
P304page(s)744-758
P577publication date2006-04-28
P1433published inBiophysical JournalQ2032955
P1476titleSingle molecule mechanical probing of the SNARE protein interactions
P478volume91