Bovine herpesvirus 1 UL49.5 protein inhibits the transporter associated with antigen processing despite complex formation with glycoprotein M.

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Bovine herpesvirus 1 UL49.5 protein inhibits the transporter associated with antigen processing despite complex formation with glycoprotein M. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.02707-05
P932PMC publication ID1472560
P698PubMed publication ID16731921
P5875ResearchGate publication ID7050781

P50authorAndrea D LipińskaQ56697640
Michał RychłowskiQ56975394
Krystyna Bieńkowska-SzewczykQ72014636
Emmanuel J H J WiertzQ96097650
P2093author name stringDanijela Koppers-Lalic
Pieter Admiraal
Andrea D Lipińska
Frans A M Rijsewijk
P2860cites workVaricelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processingQ28115772
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAPQ28239972
Bovine herpesvirus 1 glycoprotein M forms a disulfide-linked heterodimer with the U(L)49.5 proteinQ33783093
The Epstein-Barr virus (EBV) gN homolog BLRF1 encodes a 15-kilodalton glycoprotein that cannot be authentically processed unless it is coexpressed with the EBV gM homolog BBRF3.Q33785001
Complex formation by human cytomegalovirus glycoproteins M (gpUL100) and N (gpUL73).Q33813085
Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis--state of the art, June 1999.Q33868864
Intracellular surveillance: controlling the assembly of MHC class I-peptide complexesQ34156622
Fundamental and accessory systems in herpesvirusesQ34904309
Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidisQ35436549
Bovine herpesvirus 1 UL49.5 homolog gene encodes a novel viral envelope protein that forms a disulfide-linked complex with a second virion structural protein.Q35856101
The equine herpesvirus 1 glycoprotein gp21/22a, the herpes simplex virus type 1 gM homolog, is involved in virus penetration and cell-to-cell spread of virions.Q35862269
The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation.Q36242361
Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyondQ36266461
Molecular mechanism and structural aspects of transporter associated with antigen processing inhibition by the cytomegalovirus protein US6.Q38295634
Glycoproteins M and N of pseudorabies virus form a disulfide-linked complex.Q39577323
Pseudorabies virus glycoprotein M inhibits membrane fusionQ39592252
The gene 10 (UL49.5) product of equine herpesvirus 1 is necessary and sufficient for functional processing of glycoprotein M.Q39682828
Characterization of bovine herpesvirus 1 UL49 homolog gene and product: bovine herpesvirus 1 UL49 homolog is dispensable for virus growthQ39870451
Temporal control of bovine herpesvirus 1 glycoprotein synthesisQ40140944
The nonessential UL49.5 gene of infectious laryngotracheitis virus encodes an O-glycosylated protein which forms a complex with the non-glycosylated UL10 gene productQ40397292
Impaired transporter associated with antigen processing-dependent peptide transport during productive EBV infectionQ40419874
A glycoprotein M-deleted equid herpesvirus 4 is severely impaired in virus egress and cell-to-cell spread.Q40479812
Viral degradation of the MHC class I peptide loading complexQ40576858
Bovine herpesvirus 1 interferes with TAP-dependent peptide transport and intracellular trafficking of MHC class I molecules in human cells.Q40627177
Glycoproteins M and N of human herpesvirus 8 form a complex and inhibit cell fusion.Q40644363
Virus subversion of the MHC class I peptide-loading complexQ40677035
Effects of virion host shut-off activity of bovine herpesvirus 1 on MHC class I expressionQ40679399
MHC class I ubiquitination by a viral PHD/LAP finger protein.Q40773241
The UL41-encoded virion host shutoff (vhs) protein and vhs-independent mechanisms are responsible for down-regulation of MHC class I molecules by bovine herpesvirus 1.Q40784892
Equine herpesvirus 1 (EHV-1) glycoprotein M: effect of deletions of transmembrane domainsQ40837298
Model for the interaction of gammaherpesvirus 68 RING-CH finger protein mK3 with major histocompatibility complex class I and the peptide-loading complexQ41275720
Herpes simplex virus turns off the TAP to evade host immunityQ41338579
Glycoprotein M of bovine herpesvirus 1 (BHV-1) is nonessential for replication in cell culture and is involved in inhibition of bovine respiratory syncytial virus F protein induced syncytium formation in recombinant BHV-1 infected cellsQ42671928
Powering the peptide pump: TAP crosstalk with energetic nucleotidesQ44129085
Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41Q45880444
A viral inhibitor of peptide transporters for antigen presentationQ46243412
Synthesis of peptides for use as immunogensQ47845469
A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter.Q53969958
Structure of the viral TAP-inhibitor ICP47 induced by membrane associationQ73244050
P433issue12
P921main subjectBovine herpesvirus 1Q478428
P304page(s)5822-5832
P577publication date2006-06-01
P1433published inJournal of VirologyQ1251128
P1476titleBovine herpesvirus 1 UL49.5 protein inhibits the transporter associated with antigen processing despite complex formation with glycoprotein M.
P478volume80

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cites work (P2860)
Q36229606A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates
Q37064553A review of the biology of bovine herpesvirus type 1 (BHV-1), its role as a cofactor in the bovine respiratory disease complex and development of improved vaccines
Q64248581Bovine Herpesvirus 1 Counteracts Immune Responses and Immune-Surveillance to Enhance Pathogenesis and Virus Transmission
Q52316848Bovine Herpesvirus 1 UL49.5 Interacts with gM and VP22 To Ensure Virus Cell-to-Cell Spread and Virion Incorporation: Novel Role for VP22 in gM-Independent UL49.5 Virion Incorporation.
Q34064315Bovine herpesvirus type 1 (BHV-1) UL49.5 luminal domain residues 30 to 32 are critical for MHC-I down-regulation in virus-infected cells
Q43408060Bovine herpesvirus type 1 (BHV-1) mutant lacking U(L)49.5 luminal domain residues 30-32 and cytoplasmic tail residues 80-96 induces more rapid onset of virus neutralizing antibody and cellular immune responses in calves than the wild-type strain Coo
Q42690448Early, active, and specific localization of herpes simplex virus type 1 gM to nuclear membranes
Q39343105Equine herpesvirus type 4 UL56 and UL49.5 proteins downregulate cell surface major histocompatibility complex class I expression independently of each other
Q33799067Exploitation of herpesvirus immune evasion strategies to modify the immunogenicity of human mesenchymal stem cell transplants
Q91815839Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter
Q38928605Herpes simplex virus 1 gN partners with gM to modulate the viral fusion machinery.
Q37715247Herpesviruses and immunity: the art of evasion
Q37652046Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity
Q38116993Immunity to bovine herpesvirus 1: II. Adaptive immunity and vaccinology
Q34258562Molecular characterization of duck enteritis virus CHv strain UL49.5 protein and its colocalization with glycoprotein M
Q37610446Molecular mechanisms of viral immune evasion proteins to inhibit MHC class I antigen processing and presentation
Q84697437Pseudorabies virus US3- and UL49.5-dependent and -independent downregulation of MHC I cell surface expression in different cell types
Q38613277Regulation of Innate Immune Responses by Bovine Herpesvirus 1 and Infected Cell Protein 0 (bICP0).
Q40005636Signaling of a varicelloviral factor across the endoplasmic reticulum membrane induces destruction of the peptide-loading complex and immune evasion
Q24309084Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation
Q42010766Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6.
Q91648182Structure determination of UL49.5 transmembrane protein from bovine herpesvirus 1 by NMR spectroscopy and molecular dynamics
Q36986555Targeted degradation of ABC transporters in health and disease.
Q34742133The capacity of UL49.5 proteins to inhibit TAP is widely distributed among members of the genus Varicellovirus.
Q33339400Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP.
Q28083232Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution
Q37151597Viral proteins interfering with antigen presentation target the major histocompatibility complex class I peptide-loading complex

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