Predicting the effect of missense mutations on protein function: analysis with Bayesian networks (scientific article)

Genetic studies of the Lac repressor. XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure

Q30425060

Prediction of deleterious functional effects of amino acid mutations using a library of structure-based function descriptors

Q31028185

Inferring cellular networks using probabilistic graphical models

Q34295031

The Bayesian revolution in genetics

Q35766836

The SNP Consortium website: past, present and future

Q39790360

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation

Q40718968

Prediction of the phenotypic effects of non-synonymous single nucleotide polymorphisms using structural and evolutionary information.

Q45966517

Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence.

Q46020329

Bayesian approach to discovering pathogenic SNPs in conserved protein domains

Q47228584

Systematic mutation of bacteriophage T4 lysozyme.

Q50183536

P275

Creative Commons Attribution 2.0 Generic

copyrighted

main subject

protein function prediction

Q7251473

P304

page(s)

405

P577

publication date

2006-09-06

P1433

published in

BMC Bioinformatics

Q4835939

P1476

title

Predicting the effect of missense mutations on protein function: analysis with Bayesian networks

P478

volume

Reverse relations

cites work (P2860)

Q92007848	A new in silico approach to investigate molecular aspects of factor IX missense causative mutations and their impact on the hemophilia B severity
Q36976353	A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer's disease
Q30998099	AlloRep: A Repository of Sequence, Structural and Mutagenesis Data for the LacI/GalR Transcription Regulators
Q44373387	BRCA1 point mutations in premenopausal breast cancer patients from Central Sudan.
Q31114178	BioBayesNet: a web server for feature extraction and Bayesian network modeling of biological sequence data
Q51506501	Hansa: an automated method for discriminating disease and neutral human nsSNPs.
Q89698079	In Silico Identification of QTL-Based Polymorphic Genes as Salt-Responsive Potential Candidates through Mapping with Two Reference Genomes in Rice
Q35082960	Multiple co-evolutionary networks are supported by the common tertiary scaffold of the LacI/GalR proteins
Q36422240	Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression.
Q34669126	Predicting virus mutations through statistical relational learning.
Q36104137	SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity
Q30404960	Structural and functional impact of cancer-related missense somatic mutations
Q83569012	The educational role of external quality assessment in genetic testing: a 7-year experience of the European Molecular Genetics Quality Network (EMQN) in Lynch syndrome

P6409	CORE ID	81077486
P8978	DBLP publication ID	journals/bmcbi/NeedhamBBCW06
P6179	Dimensions Publication ID	1011156005
P356	DOI	10.1186/1471-2105-7-405
P953	full work available at URL	http://eprints.whiterose.ac.uk/1931/
		http://www.biomedcentral.com/1471-2105/7/405
P932	PMC publication ID	1586217
P698	PubMed publication ID	16956412
P5875	ResearchGate publication ID	6834727