Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis

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Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis is …
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scholarly articleQ13442814

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P356DOI10.1021/JM060715Y
P932PMC publication ID2517584
P698PubMed publication ID17034137
P5875ResearchGate publication ID6761439

P50authorAkram AlianQ55313191
P2093author name stringPaul R Ortiz de Montellano
Xin He
Robert Stroud
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Inhibitor binding studies on enoyl reductase reveal conformational changes related to substrate recognitionQ27619988
Molecular basis for triclosan activity involves a flipping loop in the active siteQ27620673
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Fatty acid biosynthesis as a target for novel antibacterialsQ35713880
The reductase steps of the type II fatty acid synthase as antimicrobial targetsQ36052456
Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubilityQ41982469
Neuroleptic activity and dopamine-uptake inhibition in 1-piperazino-3-phenylindansQ42241923
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesisQ42538502
Effect of detergent on "promiscuous" inhibitorsQ44523300
Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.Q44610505
Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase fromMycobacterium tuberculosis†Q62649813
Genotypic characterization of drug-resistant Mycobacterium tuberculosis isolates from PeruQ73380532
[Synthesis and vasodilative activities of benzamide derivatives]Q74121086
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium tuberculosisQ130971
P304page(s)6308-6323
P577publication date2006-10-01
P1433published inJournal of Medicinal ChemistryQ900316
P1476titlePyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
P478volume49

Reverse relations

cites work (P2860)
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