| scholarly article | Q13442814 |
| P50 | author | Stefan Kaufmann | Q2336447 |
| Alexander Visekruna | Q40157256 | ||
| Christoph Loddenkemper | Q47160857 | ||
| Ulrich Steinhoff | Q54300356 | ||
| P2093 | author name string | Martin Zeitz | |
| Daniel Seidel | |||
| Ruth Schmidt-Ullrich | |||
| Anjo Kroesen | |||
| Thorsten Joeris | |||
| P2860 | cites work | Inflammatory Bowel Disease | Q22248115 |
| A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease | Q22251291 | ||
| A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B | Q24568234 | ||
| Structure of 20S proteasome from yeast at 2.4 A resolution | Q27735081 | ||
| Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity | Q27860643 | ||
| Presentation of viral antigen controlled by a gene in the major histocompatibility complex | Q28285937 | ||
| Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway | Q28615591 | ||
| Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases | Q29547555 | ||
| Signaling to NF-kappaB | Q29547844 | ||
| Missing pieces in the NF-kappaB puzzle | Q29547864 | ||
| Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B | Q29618193 | ||
| The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B | Q29618194 | ||
| Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B | Q29618210 | ||
| Infliximab for the treatment of fistulas in patients with Crohn's disease | Q33860666 | ||
| Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides | Q34084499 | ||
| The immunological and genetic basis of inflammatory bowel disease | Q34216426 | ||
| Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease | Q34377789 | ||
| Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution | Q34440722 | ||
| The role of Th1/Th2 polarization in mucosal immunity | Q34664905 | ||
| Activation of nuclear factor kappa B inflammatory bowel disease | Q35350256 | ||
| Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages | Q35823010 | ||
| Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach | Q35967540 | ||
| The proteasome and MHC class I antigen processing | Q35967572 | ||
| A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways | Q36089051 | ||
| c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription. | Q36369604 | ||
| Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits | Q36381008 | ||
| A Failure of Transforming Growth Factor-β1 Negative Regulation Maintains Sustained NF-κB Activation in Gut Inflammation | Q38348424 | ||
| Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes | Q41527048 | ||
| Link between organ-specific antigen processing by 20S proteasomes and CD8(+) T cell-mediated autoimmunity | Q41867663 | ||
| Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes | Q41925237 | ||
| Mechanism of direct degradation of IkappaBalpha by 20S proteasome | Q42482608 | ||
| Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. | Q42840078 | ||
| Probiotics inhibit nuclear factor-kappaB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition | Q45134589 | ||
| Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. | Q45200144 | ||
| Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa | Q47787205 | ||
| Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease. | Q53649378 | ||
| MHC-linked LMP gene products specifically alter peptidase activities of the proteasome | Q59088266 | ||
| Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice | Q71472065 | ||
| Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit | Q71483389 | ||
| Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells | Q73212079 | ||
| Predominant role of NF-kappa B p65 in the pathogenesis of chronic intestinal inflammation | Q74089896 | ||
| The influence of normal microbial flora on the development of chronic mucosal inflammation | Q74552669 | ||
| Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody | Q82066058 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ulcerative colitis | Q1477 |
| P304 | page(s) | 3195-3203 | |
| P577 | publication date | 2006-11-22 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis | |
| P478 | volume | 116 |
| Q57297283 | A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS |
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| Q37301940 | A pro-inflammatory role for nuclear factor kappa B in childhood obstructive sleep apnea syndrome |
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| Q42929137 | Beneficial effects of cathepsin inhibition to prevent chemotherapy-induced intestinal mucositis. |
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| Q42524721 | Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(-/-) mice. |
| Q33675494 | Effects of a novel proteasome inhibitor BU-32 on multiple myeloma cells |
| Q37989860 | Emerging roles of immunoproteasomes beyond MHC class I antigen processing |
| Q35150799 | Enhanced inflammatory potential of CD4+ T-cells that lack proteasome immunosubunit expression, in a T-cell transfer-based colitis model |
| Q43058868 | Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis. |
| Q39096559 | Evaluation of ubiquitinated proteins by proteomics reveals the role of the ubiquitin proteasome system in the regulation of Grp75 and Grp78 chaperone proteins during intestinal inflammation |
| Q41810371 | Expression of catalytic proteasome subunits in the gut of patients with Crohn's disease |
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| Q48324393 | Glutamine enema regulates colonic ubiquitinated proteins but not proteasome activities during TNBS-induced colitis leading to increased mitochondrial activity. |
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| Q34018605 | Immunoproteasome deficiency alters retinal proteasome's response to stress |
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| Q44398790 | Impact of NF-κB gene polymorphism on allograft outcome in Hispanic renal transplant recipients. |
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| Q36627435 | Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. |
| Q54451070 | Increased proteasome-mediated degradation of occludin in irritable bowel syndrome. |
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| Q35694419 | Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets |
| Q34015431 | Interferon-γ induces immunoproteasomes and the presentation of MHC I-associated peptides on human salivary gland cells |
| Q28287063 | Lacritin-induced secretion of tear proteins from cultured monkey lacrimal acinar cells |
| Q37745110 | LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy |
| Q41653934 | Mesenchymal Stromal Cells Mitigate Experimental Colitis via Insulin-like Growth Factor Binding Protein 7-mediated Immunosuppression |
| Q38963446 | MiR-451 suppresses cell proliferation and metastasis in A549 lung cancer cells |
| Q36490739 | Mir-451 Correlates with Prognosis of Renal Cell Carcinoma Patients and Inhibits Cellular Proliferation of Renal Cell Carcinoma |
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| Q38002856 | Novel Pharmacological Approaches for Inflammatory Bowel Disease: Targeting Key Intracellular Pathways and the IL-23/IL-17 Axis |
| Q36891517 | Nuclear factor-kappaB is a critical mediator of Ste20-like proline-/alanine-rich kinase regulation in intestinal inflammation |
| Q33554513 | On to the road to degradation: atherosclerosis and the proteasome |
| Q39458419 | Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies. |
| Q40062442 | Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7. |
| Q59804795 | Proteasomal Protein Degradation: Adaptation of Cellular Proteolysis With Impact on Virus-and Cytokine-Mediated Damage of Heart Tissue During Myocarditis |
| Q34222685 | Proteasome inhibitor bortezomib ameliorates intestinal injury in mice |
| Q41788715 | Proteasome inhibitor treatment in alcoholic liver disease |
| Q50514726 | Protective effect of total alkaloids of Sophora alopecuroides on dextran sulfate sodium-induced chronic colitis |
| Q54360544 | Proteolytic activity and expression of the 20S proteasome are increased in psoriasis lesional skin. |
| Q37912201 | Proteomics to study the diversity and dynamics of proteasome complexes: from fundamentals to the clinic. |
| Q58698145 | Regulation of Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κβ) in Inflammatory Bowel Diseases |
| Q47345804 | Risk association between the NF-κB1 -94ins/delATTG promoter polymorphism and inflammatory bowel diseases: a meta-analysis |
| Q33426315 | Ste20-related proline/alanine-rich kinase (SPAK) regulated transcriptionally by hyperosmolarity is involved in intestinal barrier function |
| Q35933211 | Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity and Induces Tumor Cell Death |
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| Q37187543 | Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors |
| Q81808494 | The 3'UTR NFKBIA variant is associated with extensive colitis in Hungarian IBD patients |
| Q46120621 | The effect of proteasome inhibitor MG132 on experimental inflammatory bowel disease. |
| Q37393379 | The immunoproteasome as a target in hematologic malignancies |
| Q40906092 | The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3. |
| Q34110695 | The pathogenic potential of Campylobacter concisus strains associated with chronic intestinal diseases |
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| Q33539771 | The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes |
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| Q34534594 | Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IκBα. |
| Q45420903 | What Genetics Tells Us About the Pathogenesis of IgA Nephropathy: The Role of Immune Factors and Infection. |
| Q51459082 | α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats. |
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