| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Keith V Wood | |
| Frank Fan | |||
| P2860 | cites work | Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea | Q28189514 |
| P433 | issue | 1 | |
| P921 | main subject | bioluminescence | Q179924 |
| high-throughput screening | Q626251 | ||
| P304 | page(s) | 127-136 | |
| P577 | publication date | 2007-02-01 | |
| P1433 | published in | Assay and Drug Development Technologies | Q15767279 |
| P1476 | title | Bioluminescent assays for high-throughput screening | |
| P478 | volume | 5 |
| Q38807258 | 1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine |
| Q39593996 | A Bioluminescence Assay System for Imaging Metal Cationic Activities in Urban Aerosols. |
| Q51245716 | A Multichannel Bioluminescence Determination Platform for Bioassays. |
| Q33408924 | A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution |
| Q37668289 | A chemical screening procedure for glucocorticoid signaling with a zebrafish larva luciferase reporter system. |
| Q37402630 | A global survey identifies novel upstream components of the Ath5 neurogenic network |
| Q46239396 | A guide to design and optimization of reporter assays for 3' untranslated region mediated regulation of mammalian messenger RNAs |
| Q34779897 | A high-throughput screening assay to identify bacterial antagonists against Fusarium verticillioides |
| Q37465906 | A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT). |
| Q37490772 | A new multicolor bioluminescence imaging platform to investigate NF-κB activity and apoptosis in human breast cancer cells |
| Q34997509 | A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue |
| Q33510308 | A novel method for mining highly imbalanced high-throughput screening data in PubChem |
| Q34415623 | A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2. |
| Q64965931 | A real-time, bioluminescent annexin V assay for the assessment of apoptosis. |
| Q33347807 | A specific mechanism for nonspecific activation in reporter-gene assays |
| Q34282707 | Aminoluciferins extend firefly luciferase bioluminescence into the near-infrared and can be preferred substrates over D-luciferin |
| Q88025987 | An optimized micro-assay of myosin II ATPase activity based on the molybdenum blue method and its application in screening natural product inhibitors |
| Q38832176 | Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells |
| Q33563613 | Apparent activity in high-throughput screening: origins of compound-dependent assay interference |
| Q38787708 | Assessing activity of Hepatitis A virus 3C protease using a cyclized luciferase-based biosensor |
| Q37539812 | Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases |
| Q35190887 | BAC-based cellular model for screening regulators of BDNF gene transcription. |
| Q45214838 | Best practices for evaluation of bone marrow in nonclinical toxicity studies |
| Q33864494 | BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets |
| Q38135778 | Bioassays in natural product research - strategies and methods in the search for anti-inflammatory and antimicrobial activity |
| Q34722110 | Bioluminescence Assay for Detecting Cell Surface Membrane Protein Expression |
| Q42483578 | Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases |
| Q38080896 | Bioluminescence imaging: a shining future for cardiac regeneration. |
| Q61959384 | Bioluminescence in analytical chemistry and in vivo imaging |
| Q28476852 | Bioluminescence-based high-throughput screen identifies pharmacological agents that target neurotransmitter signaling in small cell lung carcinoma |
| Q35565594 | Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. |
| Q38017718 | Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates |
| Q92403103 | Bioluminescent imaging of Arabidopsis thaliana using an enhanced Nano-lantern luminescence reporter system |
| Q36635472 | Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System |
| Q90588942 | Building Biological Flashlights: Orthogonal Luciferases and Luciferins for in Vivo Imaging |
| Q54936124 | Cellular and Biophysical Pipeline for the Screening of Peroxisome Proliferator-Activated Receptor Beta/Delta Agonists: Avoiding False Positives. |
| Q39839789 | Chemical chaperone therapy: luciferase assay for screening of β-galactosidase mutations |
| Q42001066 | Clearly different mechanisms of enhancement of short-lived Nef-mediated viral infectivity between SIV and HIV-1. |
| Q33522759 | Comparison of bioluminescent kinase assays using substrate depletion and product formation |
| Q90479759 | Computational investigation into the fluorescence of luciferin analogues |
| Q30636976 | Considerations for designing chemical screening strategies in plant biology. |
| Q36369842 | Convergent synthesis and optical properties of near-infrared emitting bioluminescent infra-luciferins |
| Q33467337 | Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening |
| Q37791870 | Design and Implementation of High Throughput Screening Assays |
| Q50796008 | Design and Implementation of High-Throughput Screening Assays. |
| Q43032108 | Design of a coupled bioluminescent assay for a recombinant pyruvate kinase from a thermophilic Geobacillus. |
| Q39473614 | Design, conformational studies and analysis of structure-function relationships of PTH (1-11) analogues: the essential role of Val in position 2. |
| Q35535379 | Development and application of PI3K assays for novel drug discovery |
| Q89997831 | Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays |
| Q27679693 | Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography |
| Q34333972 | Development of a high-throughput Gaussia luciferase reporter assay for the activation of the GADD45a gene by mutagens, promutagens, clastogens, and aneugens. |
| Q92486717 | Discovery of chemical probes that suppress Wnt/β-catenin signaling through high-throughput screening |
| Q37140046 | Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening |
| Q41573147 | Drug Discovery by Molecular Imaging and Monitoring Therapy Response in Lymphoma. |
| Q37261080 | Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein |
| Q38298580 | ETHYLENE RESPONSE FACTOR 96 positively regulates Arabidopsis resistance to necrotrophic pathogens by direct binding to GCC elements of jasmonate - and ethylene-responsive defence genes |
| Q64250524 | Effect of Protein Conformation and AMP Protonation State on Fireflies' Bioluminescent Emission |
| Q57108215 | Elucidating the Underlying Functional Mechanisms of Breast Cancer Susceptibility Through Post-GWAS Analyses |
| Q30358152 | Epigenetic assays for chemical biology and drug discovery. |
| Q92818261 | Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis |
| Q34045557 | Evaluation of a luciferase-based reporter assay as a screen for inhibitors of estrogen-ERα-induced proliferation of breast cancer cells |
| Q33519130 | Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase |
| Q33869550 | Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase |
| Q42380666 | Evolutionary drivers of thermoadaptation in enzyme catalysis |
| Q41970983 | FRET and BRET-based biosensors in live cell compound screens |
| Q27671683 | Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter |
| Q38005367 | Firefly chemiluminescence and bioluminescence: efficient generation of excited states. |
| Q33780121 | Functional drug screening assay reveals potential glioma therapeutics |
| Q42785249 | G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells |
| Q40058694 | Genetic Tools to Study c-di-GMP-Dependent Signaling in Pseudomonas aeruginosa |
| Q53701656 | High capacity in G protein-coupled receptor signaling. |
| Q58769740 | High-Throughput Identification of Candidate Strains for Biopreservation by Using Bioluminescent |
| Q90053180 | High-Throughput Screening to Predict Chemical-Assay Interference |
| Q40534637 | High-efficient and high-content cytotoxic recording via dynamic and continuous cell-based impedance biosensor technology |
| Q27348645 | High-sensitivity real-time imaging of dual protein-protein interactions in living subjects using multicolor luciferases |
| Q35194347 | High-throughput functional screening using a homemade dual-glow luciferase assay |
| Q36885398 | High-throughput screening assays for the identification of chemical probes |
| Q52359413 | ICE1 promotes the link between splicing and nonsense-mediated mRNA decay. |
| Q57478856 | Identification of Alkaloids from W. T. Wang as Dopamine D₁ Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay |
| Q40882937 | Identification of mutant firefly luciferases that efficiently utilize aminoluciferins |
| Q28533669 | Identification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugs |
| Q28475379 | Identifying regulators for EAG1 channels with a novel electrophysiology and tryptophan fluorescence based screen |
| Q34079023 | Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology |
| Q47117264 | Imaging Cancer Metabolism |
| Q88780377 | Imaging Reporter Strategy to Monitor Gene Activation of Microglia Polarisation States under Stimulation |
| Q42235596 | Improved dual-luciferase reporter assays for nuclear receptors |
| Q35664794 | In Vitro Antiproliferative Effect of the Acetone Extract of Rubus fairholmianus Gard. Root on Human Colorectal Cancer Cells |
| Q33576021 | In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screening |
| Q50481792 | Induction of extremely low protein expression level by fusion of C-terminal region of Nef. |
| Q36538546 | Intelligent design of nano-scale molecular imaging agents |
| Q51591341 | Kinetics of inhibition of firefly luciferase by dehydroluciferyl-coenzyme A, dehydroluciferin and L-luciferin. |
| Q26830886 | Labor-effective manipulation of marine and beetle luciferases for bioassays |
| Q33499633 | Live-cell imaging of caspase activation for high-content screening |
| Q41886311 | Luciferase Reporter Assay System for Deciphering GPCR Pathways |
| Q92856246 | Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art |
| Q34014550 | Lysophosphatidylinositol causes neurite retraction via GPR55, G13 and RhoA in PC12 cells |
| Q90401284 | Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients |
| Q27022545 | Marine invertebrate xenobiotic-activated nuclear receptors: their application as sensor elements in high-throughput bioassays for marine bioactive compounds |
| Q37240957 | Matching the power of high throughput screening to the chemical diversity of natural products |
| Q37089853 | Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression |
| Q33945347 | Methodological advances in drug discovery for Chagas disease |
| Q59188873 | Modelling compound cytotoxicity using conformal prediction and PubChem HTS data |
| Q35851070 | Modular platform for low-light microscopy |
| Q27660081 | Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124 |
| Q37824281 | Molecular enigma of multicolor bioluminescence of firefly luciferase |
| Q37393034 | Monitoring the autophagy pathway in cancer |
| Q26865964 | Neuroglobin, a novel target for endogenous neuroprotection against stroke and neurodegenerative disorders |
| Q34918437 | New small molecule agonists to the thyrotropin receptor |
| Q38877342 | New winds in GPCR-based drug discovery |
| Q47900664 | Novel genetic tools to tackle c-di-GMP-dependent signalling in Pseudomonas aeruginosa. |
| Q30825133 | Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems |
| Q54965253 | Optimized application of the secreted Nano-luciferase reporter system using an affinity purification strategy. |
| Q90629203 | Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors |
| Q39716044 | Plasma protein binding of luciferase substrates influences sensitivity and accuracy of bioluminescence imaging |
| Q33346695 | Plasmodium falciparum: development of a transgenic line for screening antimalarials using firefly luciferase as the reporter |
| Q47902216 | Prediction of luciferase inhibitors by the high-performance MIEC-GBDT approach based on interaction energetic patterns |
| Q39437205 | Present and future approaches to screening of G-protein-coupled receptors |
| Q28487785 | Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays |
| Q34074697 | PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem |
| Q38708095 | Quantitative High-Throughput Screening Using a Coincidence Reporter Biocircuit |
| Q37579754 | Quantitative bioluminescence imaging of transgene expression in intact porcine antral follicles in vitro. |
| Q41639792 | Real-time assessment of Streptococcus mutans biofilm metabolism on resin composite. |
| Q35900994 | Real-time investigation of dynamic protein crystallization in living cells |
| Q38741622 | Removing the bottlenecks of cell culture metabolomics: fast normalization procedure, correlation of metabolites to cell number, and impact of the cell harvesting method |
| Q52691334 | Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system. |
| Q92209946 | Robust Normalization of Luciferase Reporter Data |
| Q40449998 | Robust light emission from cyclic alkylaminoluciferin substrates for firefly luciferase. |
| Q34480209 | Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex. |
| Q28477494 | Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach |
| Q38227133 | Split-luciferase complementary assay: applications, recent developments, and future perspectives |
| Q35108518 | Stenotrophomonas maltophilia bloodstream infection in patients with hematologic malignancies: a retrospective study and in vitro activities of antimicrobial combinations. |
| Q33866269 | Structural and dynamical insight into thermally induced functional inactivation of firefly luciferase |
| Q52727525 | Study on the effects of intermolecular interactions on firefly multicolor bioluminescence. |
| Q38592387 | Synthetic Routes to Coelenterazine and Other Imidazo[1,2-a]pyrazin-3-one Luciferins: Essential Tools for Bioluminescence-Based Investigations |
| Q34174445 | Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay |
| Q35917939 | The "TSH Receptor Glo Assay" - A High-Throughput Detection System for Thyroid Stimulation |
| Q49375826 | The Application of Non-Invasive Apoptosis Detection Sensor (NIADS) on Histone Deacetylation Inhibitor (HDACi)-Induced Breast Cancer Cell Death. |
| Q33450656 | The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase |
| Q37290283 | The challenge of selecting protein kinase assays for lead discovery optimization |
| Q58586323 | The enigmatic ATP supply of the endoplasmic reticulum |
| Q34334386 | The multicellular tumor spheroid model for high-throughput cancer drug discovery |
| Q50276213 | Theoretical modulation of the color of light emitted by firefly oxyluciferin. |
| Q27007472 | Tools for GPCR drug discovery |
| Q57147153 | Transcriptional and functional analysis of subsp. exposure to tetracycline |
| Q64086979 | Transgenic Animal Models to Visualize Cancer-Related Cellular Processes by Bioluminescence Imaging |
| Q36805228 | Translational Pharmacokinetic-Pharmacodynamic Modeling and Simulation: Optimizing 5-Fluorouracil Dosing in Children With Pediatric Ependymoma |
| Q44748416 | Update on in vitro cytotoxicity assays for drug development |
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