Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors

scientific article

Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1032811932
P356DOI10.1186/1471-213X-7-124
P932PMC publication ID2211318
P698PubMed publication ID17988375

P2093author name stringAlison D Cambrey
Kerstin J Rolfe
Adriaan O Grobbelaar
Claire Linge
Janette Richardson
Laurie M Irvine
P2860cites workCirculating insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs) and tissue mRNA levels of IGFBP-2 and IGFBP-4 in the ovine fetus.Q52208248
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.Q52241373
Keloid fibroblasts resist ceramide-induced apoptosis by overexpression of insulin-like growth factor I receptor.Q54026383
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Signal Transduction by Epidermal Growth Factor ReceptorQ58450633
Insulin-like growth factors I and II expression in the healing woundQ67516886
Enhanced expression of mRNA for insulin-like growth factor-1 in post-burn hypertrophic scar tissue and its fibrogenic role by dermal fibroblastsQ71522869
Influence of exogenous growth factors on the synthesis and secretion of collagen types I and III by explants of normal and healing rabbit ligamentsQ71859419
Myofibroblast differentiation during fibrosisQ72294291
The influence of age on collagen and non-collagen protein production by human gingival epithelial cellsQ72546389
The regulation of collagen in fetal skin wounds: mRNA localization and analysisQ72730598
Insulinlike growth factor I and interleukin 1 beta messenger RNA in a rat model of granulomatous enterocolitis and hepatitisQ72840934
IGF-I and procollagen alpha1(I) are coexpressed in a subset of mesenchymal cells in active Crohn's diseaseQ73230251
Defects of insulin and IGF-1 action at receptor and postreceptor level in a patient with type A syndrome of insulin resistanceQ73398621
Receptors: structure and functionQ77348036
Differential expression and localization of IGF-I and IGF binding proteins in inflamed rat colonQ77761878
Aging differentially modulates the expression of collagen and collagenase in dermal fibroblastsQ77952687
Insulin-like Growth Factor-I signaling mechanisms, type I collagen and alpha smooth muscle actin in human fetal lung fibroblastsQ80184705
A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transductionQ24338592
Fetal intestinal fibroblasts respond to insulin-like growth factor (IGF)-II better than adult intestinal fibroblastsQ25256707
Signal transduction by receptors with tyrosine kinase activityQ27860624
The insulin-like growth factor-binding protein (IGFBP) superfamilyQ28140850
Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1Q28286442
Molecular and cellular aspects of the insulin-like growth factor I receptorQ28288023
Constitutive phosphorylation of Shc proteins in human tumorsQ28297473
Insulin-like growth factors and their binding proteins: biological actionsQ28301853
Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factorQ28577647
Myofibroblasts. I. Paracrine cells important in health and diseaseQ33688939
Scar formation: the spectral nature of fetal and adult wound repairQ34379405
Distinct and overlapping functions of insulin and IGF-I receptorsQ34460872
Inhibition of Collagen Secretion from Bone and Cultured Fibroblasts by Microtubular Disruptive DrugsQ34699298
Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2.Q36820044
Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrationsQ38667678
Collagen in the scarless fetal skin wound: detection with picrosirius-polarization.Q39713396
Intrauterine wound healing in a 20 week human fetusQ39884123
IGF-II-mediated COX-2 gene expression in human keratinocytes through extracellular signal-regulated kinase pathwayQ40526812
Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiationQ40581730
Role of IGF system of mitogens in the induction of fibroblast proliferation by keloid-derived keratinocytes in vitroQ40666079
IGF-I and TGF-beta1 have distinct effects on phenotype and proliferation of intestinal fibroblastsQ40710505
MAP kinase kinase kinase, MAP kinase kinase and MAP kinaseQ40757575
Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK.Q40786394
Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblastsQ40835822
Differential expression of receptor tyrosine kinases and Shc in fetal and adult rat fibroblasts: toward defining scarless versus scarring fibroblast phenotypesQ40892957
Autocrine and paracrine actions of intestinal fibroblast-derived insulin-like growth factors.Q40961540
The regulation of AP-1 activity by mitogen-activated protein kinasesQ40998182
Insulin-like growth factors and inflammatory bowel diseaseQ41056187
Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblastsQ41066577
The dominant negative effect of a kinase-defective insulin receptor on insulin-like growth factor-I-stimulated signaling in Rat-1 fibroblastsQ41148452
Receptors for insulin-like growth factors I and II in developing embryonic mouse limb bud.Q41354516
Insulin-like growth factor binding proteins and their role in controlling IGF actionsQ41489957
IGF-I is required for normal embryonic growth in miceQ41510465
Expression and localization of insulin-like growth factor-1 in normal and post-burn hypertrophic scar tissue in humanQ42457781
Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.Q42610778
Mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways are not sufficient for insulin-like growth factor I-induced mitogenesis and tumorigenesisQ42800333
The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytesQ42801077
Localization of insulin-like growth factor-I in lung tissues of patients with fibroproliferative acute respiratory distress syndromeQ44262512
IGF-I increases IGFBP-5 and collagen alpha1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cellsQ44833653
Fetal wound healing. The ontogeny of scar formation in the non-human primateQ46129153
A role for TGF-beta1-induced cellular responses during wound healing of the non-scarring early human fetus?Q47597666
The expression of insulin-like growth factor (IGF)-binding protein-2 and IGF-II genes in the tissues of the developing ovine fetusQ48392660
Stimulation of steroid-suppressed cutaneous healing by repeated topical application of IGF-I: different mechanisms of action based upon the mode of IGF-I delivery.Q51112105
Differential responses of collagen and glycosaminoglycan syntheses and cell proliferation to exogenous transforming growth factor beta 1 in the developing mouse skin fibroblasts in culture.Q52171256
The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways.Q52195728
Regulation of Igf2 imprinting in development and disease.Q52203324
P921main subjectpreproinsulinQ7240673
P304page(s)124
P577publication date2007-11-07
P1433published inBMC Developmental BiologyQ15761839
P1476titleDermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors
P478volume7

Reverse relations

cites work (P2860)
Q34279592A review of fetal scarless healing
Q57170745Can host reaction animal models be used to predict and modulate skin regeneration?
Q37768345Cutaneous scarring: a clinical review.
Q37596398Direct conversion of human fibroblasts into neuronal restricted progenitors
Q51802797Effect of phytochemicals on phase II enzyme expression in infant human primary skin fibroblast cells.
Q36691084Insulin-like growth factor-II is increased in systemic sclerosis-associated pulmonary fibrosis and contributes to the fibrotic process via Jun N-terminal kinase- and phosphatidylinositol-3 kinase-dependent pathways
Q33482047Novel transcriptional profile in wrist muscles from cerebral palsy patients
Q35921159ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes

Search more.