Protein engineering of toluene monooxygenases for synthesis of chiral sulfoxides

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Protein engineering of toluene monooxygenases for synthesis of chiral sulfoxides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AEM.01849-07
P932PMC publication ID2258606
P698PubMed publication ID18192418

P50authorAyelet FishmanQ38362257
Thomas K. WoodQ38362277
P2093author name stringJanna Shainsky
Roi Feingersch
P2860cites workSWISS-MODEL: An automated protein homology-modeling serverQ24672647
X-ray Structure of a Hydroxylase−Regulatory Protein Complex from a Hydrocarbon-Oxidizing Multicomponent Monooxygenase, Pseudomonas sp. OX1 Phenol Hydroxylase † , ‡Q27640833
Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): implications for substrate gating and component interactionsQ27745648
Formation of indigo and related compounds from indolecarboxylic acids by aromatic acid-degrading bacteria: chromogenic reactions for cloning genes encoding dioxygenases that act on aromatic acidsQ28367822
Protein engineering of toluene 4-monooxygenase of Pseudomonas mendocina KR1 for synthesizing 4-nitrocatechol from nitrobenzeneQ30767708
Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradationQ31032917
Saturation mutagenesis of toluene ortho-monooxygenase of Burkholderia cepacia G4 for Enhanced 1-naphthol synthesis and chloroform degradationQ31074224
Dispelling the myths--biocatalysis in industrial synthesisQ33186387
Metagenomics and industrial applicationsQ33216319
Industrial biocatalysis today and tomorrowQ33934410
Biotransformation of organic sulfidesQ34240554
The production of fine chemicals by biotransformations.Q35025983
Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinoneQ35275351
Evolution of the soluble diiron monooxygenasesQ35556394
X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interiorQ35568292
Oxidation of benzene to phenol, catechol, and 1,2,3-trihydroxybenzene by toluene 4-monooxygenase of Pseudomonas mendocina KR1 and toluene 3-monooxygenase of Ralstonia pickettii PKO1Q35663281
Advances in biocatalytic synthesis of pharmaceutical intermediatesQ36089886
Biocatalysis for pharmaceutical intermediates: the future is now.Q36690497
Toluene 3-monooxygenase of Ralstonia pickettii PKO1 is a para-hydroxylating enzymeQ37734879
Laboratory evolution of toluene dioxygenase to accept 4-picoline as a substrateQ39492303
Toluene monooxygenase-catalyzed epoxidation of alkenesQ39536146
Characterization and application of xylene monooxygenase for multistep biocatalysisQ39649907
Functional expression of a fungal laccase in Saccharomyces cerevisiae by directed evolution.Q39708642
Mutagenesis of the "leucine gate" to explore the basis of catalytic versatility in soluble methane monooxygenase.Q40006301
Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for synthesizing 4-methylresorcinol, methylhydroquinone, and pyrogallolQ40937936
Combined participation of hydroxylase active site residues and effector protein binding in a para to ortho modulation of toluene 4-monooxygenase regiospecificityQ43894618
Crystal structure of the toluene/o-xylene monooxygenase hydroxylase from Pseudomonas stutzeri OX1. Insight into the substrate specificity, substrate channeling, and active site tuning of multicomponent monooxygenasesQ44851116
Protein engineering of toluene ortho-monooxygenase of Burkholderia cepacia G4 for regiospecific hydroxylation of indole to form various indigoid compoundsQ45004514
Controlling the regiospecific oxidation of aromatics via active site engineering of toluene para-monooxygenase of Ralstonia pickettii PKO1.Q45119178
Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for oxidizing nitrobenzene to 3-nitrocatechol, 4-nitrocatechol, and nitrohydroquinoneQ45192798
Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for enhanced chlorinated ethene degradation and o-xylene oxidationQ45254480
Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1.Q45276511
Protein modelling for allQ57075376
Recent Developments in the Synthesis and Utilization of Chiral SulfoxidesQ60401672
Stereospecific Sulfoxidation by Toluene and Naphthalene DioxygenasesQ71880156
Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenaseQ73657160
Peroxidase-catalyzed asymmetric sulfoxidation in organic solvents versus in waterQ74327471
Industrial methods for the production of optically active intermediatesQ75438744
Recent biotechnological developments in the use of peroxidasesQ77326316
Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteinsQ80104210
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecttolueneQ15779
chiralityQ214514
P304page(s)1555-1566
P577publication date2008-01-11
P1433published inApplied and Environmental MicrobiologyQ4781593
P1476titleProtein engineering of toluene monooxygenases for synthesis of chiral sulfoxides
P478volume74

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cites work (P2860)
Q38235131Biotechnological production of chiral organic sulfoxides: current state and perspectives
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Q41939203Study of the TmoS/TmoT two-component system: towards the functional characterization of the family of TodS/TodT like systems.
Q28546741The Toluene o-Xylene Monooxygenase Enzymatic Activity for the Biosynthesis of Aromatic Antioxidants
Q42064137Tuning the specificity of the recombinant multicomponent toluene o-xylene monooxygenase from Pseudomonas sp. strain OX1 for the biosynthesis of tyrosol from 2-phenylethanol
Q34061881When second best is good enough: another probabilistic look at saturation mutagenesis

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