Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits

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Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1033517783
P356DOI10.1186/1471-2172-9-6
P932PMC publication ID2275217
P698PubMed publication ID18312620
P5875ResearchGate publication ID5538911

P50authorKatri HaimilaQ75231243
Katri KaukinenQ102075472
Ilma R Korponay-SzaboQ125194834
Satumarja M StenmanQ125195169
Markku MäkiQ16989186
Jukka PartanenQ42707962
Olli LohiQ56480958
P2093author name stringKatri Lindfors
Päivi Saavalainen
Herbert Wieser
P2860cites workImmunoglobulin A autoantibodies against transglutaminase 2 in the small intestinal mucosa predict forthcoming coeliac disease.Q64966964
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Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and NutritionQ68541043
Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patientsQ71035831
In vitro toxicity of gluten peptides in coeliac disease assessed by organ cultureQ71541489
Production of antiendomysial antibodies after in-vitro gliadin challenge of small intestine biopsy samples from patients with coeliac diseaseQ71693082
Peptic-tryptic digests of gliadin: contaminating trypsin but not pepsin interferes with gastrointestinal protein binding characteristicsQ71782199
Endomysial antibody production is not related to histological damage after in vitro gluten challengeQ73403534
Forty-eight hours of biopsy culture improve the sensitivity of the in vitro gliadin challenge in the diagnosis of celiac diseaseQ74542282
In vitro production of endomysial antibodies in cultured duodenal mucosa from patients with celiac diseaseQ77319028
Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac diseaseQ77620657
Production of anti-endomysial antibodies in cultured duodenal mucosa: usefulness in coeliac disease diagnosisQ77635191
Avenin fails to induce a Th1 response in coeliac tissue following in vitro cultureQ24669749
Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody depositsQ24679813
Molecular dissection of the tissue transglutaminase autoantibody response in celiac disease.Q30657383
Association between innate response to gliadin and activation of pathogenic T cells in coeliac diseaseQ34213073
Small-bowel mucosal transglutaminase 2-specific IgA deposits in coeliac disease without villous atrophy: a prospective and randomized clinical study.Q34435922
Autoantibody targeting of brain and intestinal transglutaminase in gluten ataxiaQ34494273
In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies.Q34649501
HLA-DQ2-negative celiac disease in Finland and Spain.Q34746827
Organ culture of mucosal biopsies of human small intestineQ35572074
Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimerQ36355809
Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa.Q40481891
Missing endomysial and reticulin binding of coeliac antibodies in transglutaminase 2 knockout tissuesQ43003801
P921main subjectautoantibodyQ785022
P304page(s)6
P577publication date2008-02-29
P1433published inBMC ImmunologyQ2877163
P1476titleSecretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits
P478volume9

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cites work (P2860)
Q57937529Are Transglutaminase 2 Inhibitors Able to Reduce Gliadin-Induced Toxicity Related to Celiac Disease? A Proof-of-Concept Study
Q38364232Beyond the Intestinal Celiac Mucosa: Diagnostic Role of Anti-TG2 Deposits, a Systematic Review
Q98177686Coeliac Disease Pathogenesis: The Uncertainties of a Well-Known Immune Mediated Disorder
Q34022801Degradation of coeliac disease-inducing rye secalin by germinating cereal enzymes: diminishing toxic effects in intestinal epithelial cells.
Q38144156Diagnostic dilemmas in celiac disease
Q46057460Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease.
Q39277546Gluten-related disorders: certainties, questions and doubts
Q45220418Intestinal anti-tissue transglutaminase antibodies in potential coeliac disease.
Q87770073Intestinal titres of anti-tissue transglutaminase 2 antibodies correlate positively with mucosal damage degree and inversely with gluten-free diet duration in coeliac disease
Q37224943Isolation and culture of fibroblasts from endoscopic duodenal biopsies of celiac patients
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Q38720803Novel diagnostic techniques for celiac disease
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Q37772795Proteomic analyses lead to a better understanding of celiac disease: focus on epitope recognition and autoantibodies.
Q35685749Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease
Q47270920Usefulness of the organ culture system when villous height/crypt depth ratio, intraepithelial lymphocyte count, or serum antibody tests are not diagnostic for celiac disease

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