Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs

scientific article

Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/PROTEIN/GZM067
P698PubMed publication ID18387938
P5875ResearchGate publication ID5464488

P2093author name stringKate Jones
Ian M Tomlinson
Lucy J Holt
Amrik Basran
Jennifer Chorlton
Laurent S Jespers
Neil D Brewis
P433issue5
P921main subjectantibodyQ79460
P304page(s)283-288
P577publication date2008-04-02
P1433published inProtein Engineering Design and SelectionQ15762396
P1476titleAnti-serum albumin domain antibodies for extending the half-lives of short lived drugs
P478volume21

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cites work (P2860)
Q92239553A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer
Q33743756Adnectins: engineered target-binding protein therapeutics
Q38292087Albumin and its application in drug delivery
Q23915273Amelioration of pathology by ELR-CXC chemokine antagonism in a swine model of airway endotoxin exposure
Q34445142Anti-TNFα domain antibody construct CEP-37247: Full antibody functionality at half the size
Q37679663Antibody fragments: hope and hype
Q37998496Candidate antibody-based therapeutics against HIV-1.
Q37597698Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.
Q92585782Considerations for the Design of Antibody-Based Therapeutics
Q55284988Correlation Between Protein Primary Structure and Soluble Expression Level of HSA dAb in Escherichia coli.
Q39540318Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding
Q90211949David vs. Goliath: The Structure, Function, and Clinical Prospects of Antibody Fragments
Q34752052Development and characterization of small bispecific albumin-binding domains with high affinity for ErbB3.
Q37981866Drug development: longer-lived proteins.
Q33919030Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities
Q35044156Engineered antibody variable and constant domains as therapeutic candidates
Q42770832Escherichia coli surface display for the selection of nanobodies
Q50437891Expression of anti-tumor necrosis factor alpha (TNFα) single-chain variable fragment (scFv) in Spirodela punctata plants transformed with Agrobacterium tumefaciens
Q34568391Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain
Q39675238Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life
Q37327316Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding
Q45861473Factor IX oligomerization underlies reduced activity upon disruption of physiological conditions.
Q50948280Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection.
Q92508905Fusion of Lysostaphin to an Albumin Binding Domain Prolongs Its Half-Life and Bactericidal Activity in the Systemic Circulation
Q48191615Fusion of Ssm6a with a protein scaffold retains selectivity on NaV 1.7 and improves its therapeutic potential against chronic pain.
Q35212305Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice
Q27701821Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics
Q85342192GSK2374697, a novel albumin-binding domain antibody (AlbudAb), extends systemic exposure of exendin-4: first study in humans--PK/PD and safety
Q38989309Half-Life Extension of Biopharmaceuticals using Chemical Methods: Alternatives to PEGylation.
Q46271471Half-life extension using serum albumin-binding DARPin® domains.
Q57050328Human and mouse albumin bind their respective neonatal Fc receptors differently
Q38116457IL-1Ra and its delivery strategies: inserting the association in perspective.
Q35759488Identification of cross-reactive single-domain antibodies against serum albumin using next-generation DNA sequencing
Q38020872Immunoglobulin domains in Escherichia coli and other enterobacteria: from pathogenesis to applications in antibody technologies
Q34724092Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain
Q39167522In vitro-engineered non-antibody protein therapeutics
Q34168363Introduction to current and future protein therapeutics: a protein engineering perspective
Q38167818Latent cytokines for targeted therapy of inflammatory disorders.
Q34603307Liver-targeting of interferon-alpha with tissue-specific domain antibodies
Q50926502Modification of the Fc Region of a Human Anti-oncostatin M Monoclonal Antibody for Higher Affinity to FcRn Receptor and Extension of Half-life in Cynomolgus Monkeys.
Q38116065Monoclonal antibody treatments for rheumatoid arthritis
Q57260221Non-Antibody Scaffolds as Alternative Therapeutic Agents
Q36674580Novel Interaction Mechanism of a Domain Antibody-based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency than Ranibizumab and Bevacizumab and Improved Capacity over Aflibercept
Q37367934Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat
Q39771050Peptide aptamer microarrays: bridging the bio-detector interface.
Q35768046Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension
Q35090876Pharmacokinetic characteristics, pharmacodynamic effect and in vivo antiviral efficacy of liver-targeted interferon alpha
Q37778732Research and development of next generation of antibody-based therapeutics
Q35005394Selection of single domain antibodies from immune libraries displayed on the surface of E. coli cells with two β-domains of opposite topologies
Q39137483Selective blockade of tumor necrosis factor receptor I inhibits proinflammatory cytokine and chemokine production in human rheumatoid arthritis synovial membrane cell cultures
Q34420356Selective delivery of interleukine-1 receptor antagonist to inflamed joint by albumin fusion
Q51071921Selective tumor necrosis factor receptor I blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis factor receptor II in collagen-induced arthritis.
Q38236706Shark variable new antigen receptor biologics - a novel technology platform for therapeutic drug development
Q33449506Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation
Q90211941Single-Domain Antibodies as Therapeutic and Imaging Agents for the Treatment of CNS Diseases
Q42557601Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics
Q38217595Specific therapy to regulate inflammation in rheumatoid arthritis: molecular aspects
Q49358130Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human VH/VL Single-Domain Antibodies from In Vitro Display Libraries
Q84830552Sustained delivery of IL-1Ra from pluronic F127-based thermosensitive gel prolongs its therapeutic potentials
Q37278012Therapeutic advances in rheumatology with the use of recombinant proteins
Q37491236Therapeutic antibodies: successes, limitations and hopes for the future
Q27027238Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

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