On the mechanism of action of recombinant activated factor VII administered to patients with severe thrombocytopenia and life-threatening haemorrhage: focus on prothrombin activation

scientific article

On the mechanism of action of recombinant activated factor VII administered to patients with severe thrombocytopenia and life-threatening haemorrhage: focus on prothrombin activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1046/J.1365-2141.2002.03437.X
P698PubMed publication ID12028045
P5875ResearchGate publication ID11344397

P50authorMeyer Michel SamamaQ51732700
Patrick Van DredenQ51732717
P2093author name stringMeyer Michel Samama
Eli Karavaggeli
Grigoris T Gerotziafas
John Christakis
Kostas Zervas
Pantelis Arzoglou
Patrick Van Dreden
Stella Parashou
P2860cites workHigh-dose factor VIIa increases initial thrombin generation and mediates faster platelet activation in thrombocytopenia-like conditions in a cell-based model system.Q33338284
Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhageQ33341446
Recombinant activated factor VII (rFVIIa) therapy for intracranial hemorrhage in hemophilia A patients with inhibitorsQ45871850
Platelet activity of high-dose factor VIIa is independent of tissue factorQ45884609
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectthrombocytopeniaQ585285
internal bleedingQ2361887
P304page(s)705-708
P577publication date2002-06-01
P1433published inBritish Journal of HaematologyQ4970200
P1476titleOn the mechanism of action of recombinant activated factor VII administered to patients with severe thrombocytopenia and life-threatening haemorrhage: focus on prothrombin activation
P478volume117

Reverse relations

cites work (P2860)
Q34101751Emergency reversal of pentasaccharide anticoagulants: a systematic review of the literature
Q45877685Feasibility of using thrombin generation assay (TGA) for monitoring bypassing agent therapy in patients with hemophilia having inhibitors
Q47642467Fish as bioreactors: transgene expression of human coagulation factor VII in fish embryos.
Q50485037Intrapulmonary rFVIIa for life threatening pulmonary hemorrhage in a case of relapsing acute lymphoblastic leukemia and platelet refractoriness.
Q35839531Recombinant activated factor VII (NovoSeven): addition to replacement therapy in acute, uncontrolled and life-threatening bleeding
Q33382741Successful treatment of severe gastrointestinal bleeding after chemotherapy in acute myeloblastic leukemia with recombinant activated factor VII : report on one case and review of other uses in acute leukemias
Q45869094The intraoperative use of recombinant FVIIa in child with hemophilia A with antibodies
Q39089390The various assays for measuring activity states of factor VIIa in plasma and therapeutic products: Diagnostic value and analytical usefulness in various pathophysiological states
Q34513276Thromboembolic risks of recombinant factor VIIa Use in warfarin-associated intracranial hemorrhage: a case-control study
Q50664916Use of recombinant activated factor VII to arrest uncontrolled bleeding: a case series.

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