The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia

scientific article

The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.BIOPSYCH.2008.05.015
P698PubMed publication ID18620336

P2093author name stringDaniel Durstewitz
Jeremy K Seamans
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
dopamineQ170304
P304page(s)739-749
P577publication date2008-07-11
P1433published inBiological PsychiatryQ4914961
P1476titleThe dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia
P478volume64

Reverse relations

cites work (P2860)
Q28552297A Detailed Data-Driven Network Model of Prefrontal Cortex Reproduces Key Features of In Vivo Activity
Q50869237A Schizophrenia-Related Deletion Leads to KCNQ2-Dependent Abnormal Dopaminergic Modulation of Prefrontal Cortical Interneuron Activity.
Q36098754A Tradeoff Between Accuracy and Flexibility in a Working Memory Circuit Endowed with Slow Feedback Mechanisms
Q38160645A matched filter hypothesis for cognitive control
Q34454061A neurocomputational account of cognitive deficits in Parkinson's disease
Q38382512A perspective on neural and cognitive mechanisms of error commission.
Q36795559A quantitative system pharmacology computer model for cognitive deficits in schizophrenia
Q40991201Abrupt changes in the patterns and complexity of anterior cingulate cortex activity when food is introduced into an environment
Q38915950Activating Developmental Reserve Capacity Via Cognitive Training or Non-invasive Brain Stimulation: Potentials for Promoting Fronto-Parietal and Hippocampal-Striatal Network Functions in Old Age.
Q41816858Adaptation to recent conflict in the classical color-word Stroop-task mainly involves facilitation of processing of task-relevant information
Q42154578Adolescent stimulation of D2 receptors alters the maturation of dopamine-dependent goal-directed behavior
Q48473037Aging-related increases in behavioral variability: relations to losses of dopamine D1 receptors.
Q52673198Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition.
Q34130087Altered dopamine modulation of inhibition in the prefrontal cortex of cocaine-sensitized rats.
Q46320568Altered spatial profile of distraction in people with schizophrenia
Q35851490Amphetamine Exerts Dose-Dependent Changes in Prefrontal Cortex Attractor Dynamics during Working Memory.
Q33839379An Integrative Perspective on the Role of Dopamine in Schizophrenia
Q35157000An in vivo assay of synaptic function mediating human cognition
Q26782531An integrated network model of psychotic symptoms
Q39837691An investigation into aripiprazole's partial D₂ agonist effects within the dorsolateral prefrontal cortex during working memory in healthy volunteers
Q49892260Analysis of COMT Val158Met polymorphisms and methylation in Chinese male schizophrenia patients with homicidal behavior
Q34591845Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val108/158 Met genotype
Q36097637Assessing the synergy between cholinomimetics and memantine as augmentation therapy in cognitive impairment in schizophrenia. A virtual human patient trial using quantitative systems pharmacology
Q92515148Attentional blink and putative noninvasive dopamine markers: Two experiments to consolidate possible associations
Q27333501Attracting dynamics of frontal cortex ensembles during memory-guided decision-making
Q63888606Attractor-like Dynamics in Belief Updating in Schizophrenia
Q90058262Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating
Q44808385Behavioral Regulation and the Modulation of Information Coding in the Lateral Prefrontal and Cingulate Cortex
Q37022479Bidirectional modulation of infralimbic dopamine D1 and D2 receptor activity regulates flexible reward seeking
Q57162623Biophysical Modeling of Large-Scale Brain Dynamics and Applications for Computational Psychiatry
Q50522574Brain Signal Variability Differentially Affects Cognitive Flexibility and Cognitive Stability.
Q30596256Brain connectivity studies in schizophrenia: unravelling the effects of antipsychotics
Q35170113Brain substrates of behavioral programs associated with self-regulation
Q35575046Bridging Levels of Understanding in Schizophrenia Through Computational Modeling
Q35859549COMT Val(158)Met genotype determines the direction of cognitive effects produced by catechol-O-methyltransferase inhibition
Q28074860COMT val158met moderation of dopaminergic drug effects on cognitive function: a critical review
Q44795376COMT x DRD4 epistasis impacts prefrontal cortex function underlying response control.
Q47653254Catechol-O-methyltransferase (COMT) genotype affects cognitive control during total sleep deprivation
Q35132548Catecholamine influences on dorsolateral prefrontal cortical networks
Q92078707Catecholaminergic modulation of meta-learning
Q41846988Cell-attached single-channel recordings in intact prefrontal cortex pyramidal neurons reveal compartmentalized D1/D5 receptor modulation of the persistent sodium current
Q42652786Characterization of in vivo pharmacokinetic properties of the dopamine D1 receptor agonist DAR-0100A in nonhuman primates using PET with [11C] NNC112 and [11C] raclopride
Q38040253Cocaine-induced adaptations in metabotropic inhibitory signaling in the mesocorticolimbic system.
Q37247582Computational models of schizophrenia and dopamine modulation in the prefrontal cortex.
Q34630298Computational psychiatry.
Q36209601Conscientiousness increases efficiency of multicomponent behavior
Q91701281Cumulative Dopamine Genetic Score predicts behavioral and electrophysiological correlates of response inhibition via interactions with task demand
Q24318393DISC1 regulates primary cilia that display specific dopamine receptors
Q43705269DRD1 and DRD2 genotypes modulate processing modes of goal activation processes during action cascading.
Q58099896DRD2 methylation is associated with executive control network connectivity and severity of alcohol problems among a sample of polysubstance users
Q34508840DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia
Q37260913Decision making in recurrent neuronal circuits
Q52660523Depression: the search for separable behaviors and circuits.
Q31113942Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology
Q44190470Dexamphetamine effects on prepulse inhibition (PPI) and startle in healthy volunteers
Q37227887Dissociable fronto-striatal effects of dopamine D2 receptor stimulation on cognitive versus motor flexibility
Q90943752Dissociable roles for the ventral and dorsal medial prefrontal cortex in cue-guided risk/reward decision making
Q92576034Distinct Roles of Dopamine and Noradrenaline in Incidental Memory
Q36920310Distinct manifestations of executive dysfunction in aged rats
Q50649946Does adult ADHD interact with COMT val (158) met genotype to influence working memory performance?
Q38313013Does response inhibition have pre- and postdiagnostic utility in Parkinson's disease?
Q47865715Dopamine Alters the Fidelity of Working Memory Representations according to Attentional Demands
Q46049779Dopamine D1 versus D4 receptors differentially modulate the encoding of salient versus nonsalient emotional information in the medial prefrontal cortex
Q50626852Dopamine D2 Receptors Enhance Population Dynamics in Primate Prefrontal Working Memory Circuits.
Q43508066Dopamine D2 Receptors Modulate Pyramidal Neurons in Mouse Medial Prefrontal Cortex through a Stimulatory G-Protein Pathway
Q52641131Dopamine D2 agonist affects visuospatial working memory distractor interference depending on individual differences in baseline working memory span.
Q36595342Dopamine Does Double Duty in Motivating Cognitive Effort.
Q33729433Dopamine and psychosis: theory, pathomechanisms and intermediate phenotypes
Q50781089Dopamine effects on human error processing depend on catechol-O-methyltransferase VAL158MET genotype.
Q97093691Dopamine manipulations modulate paranoid social inferences in healthy people
Q47821448Dopamine modulates frontomedial failure processing of agentic introverts versus extraverts in incentive contexts.
Q33490598Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex
Q38241529Dopamine modulation of learning and memory in the prefrontal cortex: insights from studies in primates, rodents, and birds
Q49130696Dopamine regulates two classes of primate prefrontal neurons that represent sensory signals.
Q90249525Dopamine tunes prefrontal outputs to orchestrate aversive processing
Q41226794Dopaminergic Genetic Polymorphisms Predict Rule-based Category Learning
Q37279397Dopaminergic control of cognitive flexibility in humans and animals
Q34994120Dopaminergic genes predict individual differences in susceptibility to confirmation bias
Q48491409Dopaminergic modulation of distracter-resistance and prefrontal delay period signal
Q47953882Dose-Dependent Effects of Oral Tyrosine Administration on Plasma Tyrosine Levels and Cognition in Aging
Q43513506Double dissociation of dopamine genes and timing in humans
Q36792613Dynamic Connectivity between Brain Networks Supports Working Memory: Relationships to Dopamine Release and Schizophrenia
Q38174532Dysfunctions of decision-making and cognitive control as transdiagnostic mechanisms of mental disorders: advances, gaps, and needs in current research.
Q46802114EEG Source Imaging Indices of Cognitive Control Show Associations with Dopamine System Genes.
Q42010840Effects of COMT genotype on sensory gating and its modulation by nicotine: Differences in low and high P50 suppressors
Q39897250Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats
Q37375548Effects of Ginkgo biloba extract EGb 761® on cognitive control functions, mental activity of the prefrontal cortex and stress reactivity in elderly adults with subjective memory impairment - a randomized double-blind placebo-controlled trial
Q47334550Effects of positive emotion, extraversion, and dopamine on cognitive stability-flexibility and frontal EEG asymmetry
Q50050296Effects of tolcapone and bromocriptine on cognitive stability and flexibility
Q42291162Electrophysiological Evidence for Hyperfocusing of Spatial Attention in Schizophrenia
Q33570015Enhanced frontal function in Parkinson's disease
Q50435318Event-related potentials reflect impaired temporal interval learning following haloperidol administration
Q45401709Examining belief and confidence in schizophrenia
Q37955547Excitation, inhibition, local oscillations, or large-scale loops: what causes the symptoms of schizophrenia?
Q55028716Executive Function Deficits in Seriously Ill Children-Emerging Challenges and Possibilities for Clinical Care.
Q42585788Executive functions and prefrontal cortex: a matter of persistence?
Q29301208Exploration versus exploitation in space, mind, and society
Q38173746Exploring the cognitive and motor functions of the basal ganglia: an integrative review of computational cognitive neuroscience models
Q50080406Fractionating the Neurocognitive Mechanisms Underlying Working Memory: Independent Effects of Dopamine and Parkinson's Disease.
Q47200572From Maps to Multi-dimensional Network Mechanisms of Mental Disorders
Q39818506From maps to mechanisms through neuroimaging of schizophrenia
Q48514460Frontostriatal Contribution to the Interplay of Flexibility and Stability in Serial Prediction
Q42852530Frontostriatal involvement in task switching depends on genetic differences in d2 receptor density.
Q37424596Genetic polymorphisms regulating dopamine signaling in the frontal cortex interact to affect target detection under high working memory load.
Q91584458Genetic variation in dopamine availability modulates the self-reported level of action control in a sex-dependent manner
Q57183263High Sensitivity Mapping of Cortical Dopamine D2 Receptor Expressing Neurons
Q36077639How much of reinforcement learning is working memory, not reinforcement learning? A behavioral, computational, and neurogenetic analysis
Q35534224Human cognitive flexibility depends on dopamine D2 receptor signaling
Q34490440Hyperfocusing in schizophrenia: Evidence from interactions between working memory and eye movements
Q92749975Identifying nonlinear dynamical systems via generative recurrent neural networks with applications to fMRI
Q36750941Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia
Q61135966Impaired recruitment of dopamine neurons during working memory in mice with striatal D2 receptor overexpression
Q55178527Impaired serial ordering in nondemented patients with mild Parkinson's disease.
Q35166818Improper activation of D1 and D2 receptors leads to excess noise in prefrontal cortex
Q90060019Increased dopamine availability magnifies nicotine effects on cognitive control: A pilot study
Q42367539Individual differences in eye blink rate predict both transient and tonic pupil responses during reversal learning.
Q39249046Integrating Spatial Working Memory and Remote Memory: Interactions between the Medial Prefrontal Cortex and Hippocampus
Q37670390Integration of Advance Information about a Forthcoming Task Switch - Evidence from Eye Blink Rates.
Q55378329Interaction of childhood urbanicity and variation in dopamine genes alters adult prefrontal function as measured by functional magnetic resonance imaging (fMRI).
Q64885048Interactions of Motivation and Cognitive Control.
Q35035569Inverted-U-shaped dopamine actions on human working memory and cognitive control
Q48020452Latent-Profile Analysis Reveals Behavioral and Brain Correlates of Dopamine-Cognition Associations
Q58880976Local Cortical Dynamics Related to Mental Illnesses
Q35185785Mechanisms of motivation-cognition interaction: challenges and opportunities
Q27324845Memory impairment and alterations in prefrontal cortex gamma band activity following methamphetamine sensitization
Q30588578Modeling dopaminergic and other processes involved in learning from reward prediction error: contributions from an individual differences perspective
Q100423058Multimodal investigation of dopamine D2/D3 receptors, default mode network suppression, and cognitive control in cocaine-use disorder
Q35956687Neural Substrates of Dopamine D2 Receptor Modulated Executive Functions in the Monkey Prefrontal Cortex
Q30453655Neural masses and fields in dynamic causal modeling
Q38527118Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models.
Q38203026Neural oscillations during non-rapid eye movement sleep as biomarkers of circuit dysfunction in schizophrenia
Q92648272Neural substrates of early executive function development
Q24602643Neurogenetics and pharmacology of learning, motivation, and cognition
Q47280486Neuromodulatory Systems and Their Interactions: A Review of Models, Theories, and Experiments
Q24630528Neurophysiological and Computational Principles of Cortical Rhythms in Cognition
Q36225226No association of catechol-O-methyltransferase polymorphisms with schizophrenia in the Han Chinese population
Q44259499Nonlinear dose-dependent impact of D1 receptor activation on motor cortex plasticity in humans.
Q38211498Optogenetic approaches for investigating neural pathways implicated in schizophrenia and related disorders.
Q34660762Optogenetic dissection of medial prefrontal cortex circuitry
Q42405592Orbitofrontal (18) F-DOPA Uptake and Movement Preparation in Parkinson's Disease
Q47942321Parallel maturation of goal-directed behavior and dopaminergic systems during adolescence.
Q36904284Perseveration and choice in Parkinson's disease: the impact of progressive frontostriatal dysfunction on action decisions
Q38755718Positive affect versus reward: emotional and motivational influences on cognitive control
Q30529812Prefrontal D2-receptor stimulation mediates flexible adaptation of economic preference hierarchies.
Q36185520Prefrontal Markers and Cognitive Performance Are Dissociated during Progressive Dopamine Lesion.
Q47965687Prefrontal cortical mechanisms underlying individual differences in cognitive flexibility and stability
Q35844242Prefrontal dopamine and the dynamic control of human long-term memory
Q38252882Prefrontal dopamine in associative learning and memory.
Q48650321Prefrontal dopamine levels determine the balance between cognitive stability and flexibility
Q37254819Putative cortical dopamine levels affect cortical recruitment during planning.
Q33906454Reduced capacity but spared precision and maintenance of working memory representations in schizophrenia
Q33666603Relating dopaminergic and cholinergic polymorphisms to spatial attention in infancy
Q44193437Relationship of frontal D(2/3) binding potentials to cognition: a study of antipsychotic-naive schizophrenia patients
Q34322982Relationships between divided attention and working memory impairment in people with schizophrenia
Q46395989Remote memories are enhanced by COMT activity through dysregulation of the endocannabinoid system in the prefrontal cortex.
Q36924080Repeated cocaine exposure increases fast-spiking interneuron excitability in the rat medial prefrontal cortex.
Q36672569Reward Motivation Enhances Task Coding in Frontoparietal Cortex.
Q48738298Reward acts on the pFC to enhance distractor resistance of working memory representations
Q35546464Severe Myoclonic Epilepsy in Infancy - Adult Phenotype with Bradykinesia, Hypomimia, and Perseverative Behavior: Report of Five Cases
Q34460451Smooth pursuit and visual occlusion: active inference and oculomotor control in schizophrenia
Q91768352Stability and flexibility in cognitive control: Interindividual dynamics and task context processing
Q35661806Stochastic Dynamics Underlying Cognitive Stability and Flexibility
Q35423597Striatal D1- and D2-type dopamine receptors are linked to motor response inhibition in human subjects
Q37909949Striatal Dopamine and the Interface between Motivation and Cognition
Q58765692Superior cognitive goal maintenance in carriers of genetic markers linked to reduced striatal D2 receptor density (C957T and DRD2/ANKK1-TaqIA)
Q55313143Synaptic Effects of Dopamine Breakdown and Their Relation to Schizophrenia-Linked Working Memory Deficits.
Q35961970Synaptic activity unmasks dopamine D2 receptor modulation of a specific class of layer V pyramidal neurons in prefrontal cortex
Q83231320Task-induced functional brain connectivity mediates the relationship between striatal D2/3 receptors and working memory
Q50667216The COMT Val158Met polymorphism regulates the effect of a dopamine antagonist on the feedback-related negativity.
Q48459961The Neurocognitive Cost of Enhancing Cognition with Methylphenidate: Improved Distractor Resistance but Impaired Updating
Q92258548The Role of DRD1 and DRD2 Receptors for Response Selection Under Varying Complexity Levels: Implications for Metacontrol Processes
Q60951051The Role of Frontostriatal Systems in Instructed Reinforcement Learning: Evidence From Genetic and Experimentally-Induced Variation
Q37118481The association between creativity and 7R polymorphism in the dopamine receptor D4 gene (DRD4)
Q30854959The cognitive neuroscience of working memory
Q38923432The costs and benefits of brain dopamine for cognitive control
Q47899959The differential influences of positive affect, random reward, and performance-contingent reward on cognitive control.
Q48307366The dynamic balance between cognitive flexibility and stability: the influence of local changes in reward expectation and global task context on voluntary switch rate
Q38049561The neurobiology and neural circuitry of cognitive changes in Parkinson's disease revealed by functional neuroimaging
Q50637926The role of dopamine in motor flexibility.
Q30437188The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue
Q34229826The role of the rat medial prefrontal cortex in adapting to changes in instrumental contingency
Q92552757Theory of Event Coding (TEC) V2.0: Representing and controlling perception and action
Q21136367Thinking outside a less intact box: thalamic dopamine D2 receptor densities are negatively related to psychometric creativity in healthy individuals
Q45776671Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex
Q48444058Tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys
Q46536175Tonic or Phasic Stimulation of Dopaminergic Projections to Prefrontal Cortex Causes Mice to Maintain or Deviate from Previously Learned Behavioral Strategies.
Q39478402Touchscreen-paradigm for mice reveals cross-species evidence for an antagonistic relationship of cognitive flexibility and stability
Q36904288Toward the neural mechanisms of reduced working memory capacity in schizophrenia
Q41407879Understanding responder neurobiology in schizophrenia using a quantitative systems pharmacology model: application to iloperidone
Q42144978Unique and shared roles of the posterior parietal and dorsolateral prefrontal cortex in cognitive functions
Q89824789Variability in Action Selection Relates to Striatal Dopamine 2/3 Receptor Availability in Humans: A PET Neuroimaging Study Using Reinforcement Learning and Active Inference Models
Q36507759Variability in Dopamine Genes Dissociates Model-Based and Model-Free Reinforcement Learning
Q37024867Variation in Dopamine D2 and Serotonin 5-HT2A Receptor Genes is Associated with Working Memory Processing and Response to Treatment with Antipsychotics
Q47913013What part of working memory is not working in ADHD? Short-term memory, the central executive and effects of reinforcement
Q37130928Working memory and anticipatory set modulate midbrain and putamen activity

Search more.