| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Bernd Nilius | Q823958 |
| Thomas Voets | Q40270934 | ||
| P2860 | cites work | Mutations in the TRPV4 gene are not associated with sporadic progressive muscular atrophy | Q84357276 |
| Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls | Q84696423 | ||
| OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity | Q24290380 | ||
| Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking | Q24295521 | ||
| Ca2+-dependent Potentiation of the Nonselective Cation Channel TRPV4 Is Mediated by a C-terminal Calmodulin Binding Site | Q24300879 | ||
| An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure | Q24302551 | ||
| Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations | Q24305183 | ||
| The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels | Q24316916 | ||
| Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C | Q24595706 | ||
| Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis | Q24614844 | ||
| Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor | Q24647926 | ||
| Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels † , ‡ | Q27649734 | ||
| Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C | Q27658802 | ||
| Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel | Q27681184 | ||
| The Hammersmith functional motor scale for children with spinal muscular atrophy: a scale to test ability and monitor progress in children with limited ambulation | Q28187554 | ||
| PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4 | Q28506144 | ||
| Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells | Q28576188 | ||
| Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3 | Q28586640 | ||
| TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis | Q28586703 | ||
| Microfilament-associated Protein 7 Increases the Membrane Expression of Transient Receptor Potential Vanilloid 4 (TRPV4) | Q28588227 | ||
| The role of the membrane potential in chondrocyte volume regulation | Q28741991 | ||
| Structure-function relationship of the TRP channel superfamily. | Q30354022 | ||
| Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathies | Q30495788 | ||
| CMT2C with vocal cord paresis associated with short stature and mutations in the TRPV4 gene | Q30497795 | ||
| Abnormal osmotic regulation in trpv4 -/- mice | Q30501210 | ||
| Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis | Q30520617 | ||
| Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4. | Q30547553 | ||
| TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels. | Q33226567 | ||
| Identification and characterization of novel TRPV4 modulators | Q33500893 | ||
| Genetic disorders of the skeleton: a developmental approach | Q33906292 | ||
| Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force | Q34094517 | ||
| Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives | Q34112760 | ||
| TRPV4 related skeletal dysplasias: a phenotypic spectrum highlighted byclinical, radiographic, and molecular studies in 21 new families. | Q34191229 | ||
| TRPV4 mutations in children with congenital distal spinal muscular atrophy | Q34270323 | ||
| TRPV4-associated skeletal dysplasias | Q34287791 | ||
| Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia | Q34790129 | ||
| IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site. | Q34841332 | ||
| Mutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies. | Q34948196 | ||
| Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia | Q34949511 | ||
| The vanilloid transient receptor potential channel TRPV4: from structure to disease | Q35008291 | ||
| TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. | Q35044737 | ||
| Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4. | Q35123129 | ||
| Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth. | Q35774155 | ||
| Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding | Q36072783 | ||
| Fetal akinesia in metatropic dysplasia: The combined phenotype of chondrodysplasia and neuropathy? | Q57234082 | ||
| Striking phenotypic variability in familial TRPV4-axonal neuropathy spectrum disorder | Q57915582 | ||
| Muscle MRI in TRPV4-related congenital distal SMA | Q58554381 | ||
| Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells | Q80681938 | ||
| OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum | Q81431465 | ||
| Channelopathies converge on TRPV4 | Q82659974 | ||
| TRPV4 neuropathies: calcium channel inhibition as a therapeutic target? | Q83355853 | ||
| Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes | Q83531896 | ||
| TRPV4-pathy manifesting both skeletal dysplasia and peripheral neuropathy: a report of three patients | Q83655641 | ||
| TRP channels and pain | Q83830678 | ||
| Calcium/calmodulin-signaling supports TRPV4 activation in osteoclasts and regulates bone mass | Q83856769 | ||
| Exome sequencing identifies a novel TRPV4 mutation in a CMT2C family | Q36078457 | ||
| Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel. | Q36153290 | ||
| Human skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation | Q36514432 | ||
| Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function. | Q37026223 | ||
| A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia | Q37310734 | ||
| Molecular mechanisms of TRPV4-mediated neural signaling | Q37348481 | ||
| Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system? | Q37730961 | ||
| TRPV4-mediated channelopathies | Q37777016 | ||
| The transient receptor potential family of ion channels | Q37852820 | ||
| Therapeutic targeting of TRP channels--the TR(i)P to pain relief | Q37889348 | ||
| Molecular genetics and mechanisms of disease in distal hereditary motor neuropathies: insights directing future genetic studies | Q37929244 | ||
| The distal hereditary motor neuropathies. | Q37949568 | ||
| Genetics of neuropathies | Q37977840 | ||
| TRPV4 axonal neuropathy spectrum disorder | Q38012267 | ||
| The TRPM8 ion channel comprises direct Gq protein-activating capacity | Q39372111 | ||
| Mutations in TRPV4 cause an inherited arthropathy of hands and feet. | Q39464645 | ||
| Ligand stoichiometry of the cold- and menthol-activated channel TRPM8. | Q39482079 | ||
| TRPV4 mutations and cytotoxic hypercalcemia in axonal Charcot-Marie-Tooth neuropathies. | Q39598965 | ||
| Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study | Q39861832 | ||
| Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation | Q40084522 | ||
| Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. | Q40162647 | ||
| Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells | Q40700786 | ||
| A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels | Q41644878 | ||
| TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals | Q41980369 | ||
| Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers. | Q42363286 | ||
| Molecular determinants of permeation through the cation channel TRPV4. | Q44047575 | ||
| Impaired Pressure Sensation in Mice Lacking TRPV4 | Q44401201 | ||
| Modulation of TRPV4 gating by intra- and extracellular Ca2+. | Q44452825 | ||
| Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels | Q44524443 | ||
| TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts | Q45749407 | ||
| Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation | Q46444337 | ||
| Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. | Q46716856 | ||
| Functional expression of transient receptor potential vanilloid 4 in the mouse cochlea | Q46890787 | ||
| Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells | Q47406703 | ||
| Hearing impairment in TRPV4 knockout mice | Q48878721 | ||
| Peripheral neuropathies: Molecular diagnosis of Charcot-Marie-Tooth disease. | Q50536282 | ||
| PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries. | Q50716747 | ||
| Dominant TRPV4 mutations in nonlethal and lethal metatropic dysplasia. | Q51909616 | ||
| Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family. | Q54422608 | ||
| Spondylo-epiphyseal dysplasia, Maroteaux type (pseudo-Morquio syndrome type 2), and parastremmatic dysplasia are caused by TRPV4 mutations. | Q55052943 | ||
| A large New England kindred with autosomal dominant neurogenic scapuloperoneal amyotrophy with unique features | Q56008635 | ||
| N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Pa | Q56601579 | ||
| P433 | issue | 2 | |
| P304 | page(s) | 152-163 | |
| P577 | publication date | 2013-01-11 | |
| P1433 | published in | EMBO Reports | Q5323356 |
| P1476 | title | The puzzle of TRPV4 channelopathies | |
| P478 | volume | 14 |
| Q35910190 | A channelopathy mechanism revealed by direct calmodulin activation of TrpV4. |
| Q37369327 | A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open |
| Q92690681 | Activation of PTEN by inhibition of TRPV4 suppresses colon cancer development |
| Q36627414 | Activation of TRPV4 Regulates Respiration through Indirect Activation of Bronchopulmonary Sensory Neurons |
| Q48455462 | Activation of Transient Receptor Potential Vanilloid 4 is Involved in Neuronal Injury in Middle Cerebral Artery Occlusion in Mice |
| Q34356405 | Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells |
| Q58861707 | Autosomal dominant brachyolmia in a large Swedish family: Phenotypic spectrum and natural course |
| Q37644143 | Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice. |
| Q38830295 | Calcium Entry Through Thermosensory Channels |
| Q38175134 | Calcium-permeable ion channels in pain signaling |
| Q27333728 | Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis |
| Q24601791 | Channelopathies |
| Q63170642 | Charcot-Marie-Tooth disease type 2C and scapuloperoneal muscular atrophy overlap syndrome in a patient with the R232C TRPV4 mutation |
| Q52087282 | Compound heterozygous TRPV4 mutations in two siblings with a complex phenotype including severe intellectual disability and neuropathy. |
| Q52684303 | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms. |
| Q35086473 | Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron |
| Q36363007 | Detection of TRPV4 channel current-like activity in Fawn Hooded hypertensive (FHH) rat cerebral arterial muscle cells |
| Q37012415 | Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C. |
| Q48091207 | Endogenous TRPV4 Expression of a Hybrid Neuronal Cell Line N18D3 and Its Utilization to Find a Novel Synthetic Ligand. |
| Q92610238 | Endothelial TRPV4 channels modulate vascular tone by Ca2+ -induced Ca2+ release at inositol 1,4,5-trisphosphate receptors |
| Q38203224 | Environmental temperature impact on bone and cartilage growth |
| Q97527143 | Exome sequencing for diagnosis of congenital hemolytic anemia |
| Q33613251 | Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations |
| Q30276535 | Gain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral head |
| Q37359002 | High-resolution views of TRPV1 and their implications for the TRP channel superfamily |
| Q90213262 | Human mutations highlight an intersubunit cation-π bond that stabilizes the closed but not open or inactivated states of TRPV channels |
| Q53185404 | Increased Expression of Transient Receptor Potential Vanilloid 4 in Cortical Lesions of Patients with Focal Cortical Dysplasia. |
| Q38788297 | Integrative and comparative reproductive biology: From alligators to xenobiotics |
| Q48097842 | Intrafamilial variable hearing loss in TRPV4 induced spinal muscular atrophy |
| Q64230659 | Ion Channel Contributions to Wing Development in |
| Q35212642 | L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel |
| Q38425447 | MLC1 protein: a likely link between leukodystrophies and brain channelopathies |
| Q28834419 | Mechanical dynamics in live cells and fluorescence-based force/tension sensors |
| Q41609420 | Mechanosensitive Ion Channels in Cardiovascular Physiology |
| Q27024474 | MscS-like mechanosensitive channels in plants and microbes |
| Q36766834 | Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome |
| Q92969840 | Novel gain-of-function mutation of TRPV4 associated with accelerated chondrogenic differentiation of dental pulp stem cells derived from a patient with metatropic dysplasia |
| Q36738586 | Novel mutations highlight the key role of the ankyrin repeat domain in TRPV4-mediated neuropathy |
| Q90613889 | PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation |
| Q37477352 | PNPLA6 mutations cause Boucher-Neuhauser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum |
| Q54982587 | Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity. |
| Q33788974 | Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1 |
| Q47205429 | Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes |
| Q38222958 | Phosphoinositide regulation of TRP channels |
| Q36945667 | Phosphoinositide signaling in somatosensory neurons |
| Q35548090 | Phosphorylation on TRPV4 Serine 824 Regulates Interaction with STIM1. |
| Q50211745 | Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2. |
| Q58553478 | Polymodal TRPV1 and TRPV4 Sensors Colocalize but Do Not Functionally Interact in a Subpopulation of Mouse Retinal Ganglion Cells |
| Q26822505 | Regulation of transient receptor potential channels by the phospholipase C pathway |
| Q39060342 | Renoprotection: focus on TRPV1, TRPV4, TRPC6 and TRPM2. |
| Q46537959 | SMD Kozlowski type caused by p.Arg594His substitution in TRPV4 reveals abnormal ossification and notochordal remnants in discs and vertebrae |
| Q48600823 | Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase |
| Q38368325 | Sensory TRP channels: the key transducers of nociception and pain. |
| Q35750599 | Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells |
| Q42340252 | Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients |
| Q57752466 | Structural Basis of TRPV4 N Terminus Interaction with Syndapin/PACSIN1-3 and PIP |
| Q57183523 | Structural biology of TRP channels |
| Q41620398 | Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel. |
| Q34537097 | Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia |
| Q58788337 | TRP Channels as Sensors of Bacterial Endotoxins |
| Q33562153 | TRP channels in lower urinary tract dysfunction |
| Q48897326 | TRPM2 mediates the lysophosphatidic acid-induced neurite retraction in the developing brain |
| Q89763845 | TRPM3_miR-204: a complex locus for eye development and disease |
| Q38116973 | TRPV3: a 'more than skinny' channel |
| Q52595247 | TRPV4 Blockade Preserves the Blood-Brain Barrier by Inhibiting Stress Fiber Formation in a Rat Model of Intracerebral Hemorrhage. |
| Q88552213 | TRPV4 Does Not Regulate the Distal Retinal Light Response |
| Q59130173 | TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination |
| Q58054909 | TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw |
| Q35181627 | TRPV4 as a therapeutic target for joint diseases. |
| Q36382597 | TRPV4 associates environmental temperature and sex determination in the American alligator |
| Q27695648 | TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P₂ |
| Q37234560 | TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension |
| Q92155424 | TRPV4 deletion protects against hypokalemia during systemic K+ deficiency |
| Q37543793 | TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. |
| Q38262420 | TRPV4: physiological role and therapeutic potential in respiratory diseases |
| Q38222954 | TRPs: modulation by drug-like compounds |
| Q48326480 | Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field. |
| Q55084359 | The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity. |
| Q38216887 | The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements |
| Q26744730 | Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery |
| Q93083710 | Thiemann disease and familial digital arthropathy - brachydactyly: two sides of the same coin? |
| Q52807139 | Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion. |
| Q48414139 | Transient Receptor Potential Vanilloid 4-Induced Modulation of Voltage-Gated Sodium Channels in Hippocampal Neurons |
| Q92266170 | Transient Receptor Potential vanilloid 4 ion channel in C-fibres is involved in mechanonociception of the normal and inflamed joint |
| Q33562143 | Transient receptor potential (TRP) channels: a clinical perspective |
| Q26849317 | Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine |
| Q49806546 | Transient receptor potential vanilloid 4 (TRPV4) activation by arachidonic acid requires protein kinase A-mediated phosphorylation |
| Q38743122 | Transient receptor potential vanilloid 4 (TRPV4) silencing in Helicobacter pylori-infected human gastric epithelium. |
| Q38704567 | Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction |
| Q36584629 | Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias |
| Q38222961 | What do we really know and what do we need to know: some controversies, perspectives, and surprises |
| Q47228512 | When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor. |
| Q47124322 | X-linked hypomyelination with spondylometaphyseal dysplasia (H-SMD) associated with mutations in AIFM1. |
| Q39630828 | Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4. |
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