The paradox of bardoxolone methyl: a call for every witness on the stand?

scientific article

The paradox of bardoxolone methyl: a call for every witness on the stand? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/DOM.12356
P698PubMed publication ID25041694
P5875ResearchGate publication ID263931812

P2093author name stringR Vanholder
W Van Biesen
S Van Laecke
P2860cites workCirculating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studiesQ26828820
A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammationQ26850196
Hypomagnesaemia, the kidney and the vesselsQ26853709
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Relations of dietary magnesium intake to biomarkers of inflammation and endothelial dysfunction in an ethnically diverse cohort of postmenopausal womenQ33602201
Avosentan for overt diabetic nephropathyQ33702404
Bardoxolone methyl and kidney function in CKD with type 2 diabetesQ34194954
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomasQ34277465
Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney diseaseQ34383685
Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methylQ34423200
Comparison of treatment effect sizes associated with surrogate and final patient relevant outcomes in randomised controlled trials: meta-epidemiological studyQ34567058
Cation dyshomeostasis and cardiomyocyte necrosis: the Fleckenstein hypothesis revisitedQ35138063
Bardoxolone methyl decreases megalin and activates nrf2 in the kidneyQ36280389
Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.Q36410781
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney diseaseQ36788430
Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular diseaseQ37073587
Endothelial-podocyte crosstalk: the missing link between endothelial dysfunction and albuminuria in diabetesQ37251105
Low serum magnesium and cardiovascular mortality in chronic heart failure: a propensity-matched studyQ37289665
Endothelial cells and magnesium: implications in atherosclerosisQ37976136
Endothelin antagonists in hypertension and kidney diseaseQ38052428
Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patientsQ41955256
Magnesium orotate in severe congestive heart failure (MACH).Q43416048
Analogs of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effectsQ43475358
Novel metabolic risk factors for incident heart failure and their relationship with obesity: the MESA (Multi-Ethnic Study of Atherosclerosis) studyQ43598066
Hypomagnesemia and the risk of death and GFR decline in chronic kidney diseaseQ43767561
Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart StudyQ44433022
Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in middle-aged and elderly subjects with no apparent heart diseaseQ44806693
Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity.Q45926436
Characterization of CD45-/CD31+/CD105+ circulating cells in the peripheral blood of patients with gynecologic malignanciesQ47841392
Serum ionized magnesium levels in relation to metabolic syndrome in type 2 diabetic patients.Q51496620
Bardoxolone Methyl, Chronic Kidney Disease, and Type 2 DiabetesQ56775182
Hypomagnesemia is a significant predictor of cardiovascular and non-cardiovascular mortality in patients undergoing hemodialysisQ58362776
P433issue1
P304page(s)9-14
P577publication date2014-08-04
P1433published inDiabetes, Obesity and MetabolismQ5270109
P1476titleThe paradox of bardoxolone methyl: a call for every witness on the stand?
P478volume17

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cites work (P2860)
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