| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Alan L Harvey | |
| P433 | issue | 19-20 | |
| P921 | main subject | natural product | Q901227 |
| drug discovery | Q1418791 | ||
| P304 | page(s) | 894-901 | |
| P577 | publication date | 2008-08-22 | |
| P1433 | published in | Drug Discovery Today | Q3040085 |
| P1476 | title | Natural products in drug discovery | |
| P478 | volume | 13 |
| Q34253331 | 11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus. |
| Q90523135 | A Combination of Linalool, Vitamin C, and Copper Synergistically Triggers Reactive Oxygen Species and DNA Damage and Inhibits Salmonella enterica subsp. enterica Serovar Typhi and Vibrio fluvialis |
| Q38488241 | A Comprehensive Review on the Phytochemical Constituents and Pharmacological Activities of Pogostemon cablin Benth.: An Aromatic Medicinal Plant of Industrial Importance. |
| Q91813256 | A Highly Active Triterpene Derivative Capable |of Biofilm Damage to Control Cryptococcus spp |
| Q40726547 | A Metabolomic Approach to Target Compounds from the Asteraceae Family for Dual COX and LOX Inhibition |
| Q52822011 | A Preclinical Evaluation of the Antitumor Activities of Edible and Medicinal Mushrooms: A Molecular Insight. |
| Q35973103 | A chemical family-based strategy for uncovering hidden bioactive molecules and multicomponent interactions in herbal medicines. |
| Q34543267 | A chemogenomic analysis of ionization constants--implications for drug discovery |
| Q42003848 | A chemoinformatics approach to the discovery of lead-like molecules from marine and microbial sources en route to antitumor and antibiotic drugs. |
| Q92107770 | A comprehensive review of computational techniques for the prediction of drug side effects |
| Q48626870 | A diversity oriented synthesis of natural product inspired molecular libraries. |
| Q93133678 | A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings |
| Q28607543 | A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins |
| Q98781281 | A nontoxic fungal natural product modulates fin regeneration in zebrafish larvae upstream of FGF-WNT developmental signaling |
| Q48357538 | A novel caffeoyl triterpene attenuates cerebral ischemic injury with potent anti-inflammatory and hypothermic effects |
| Q28535225 | A novel compound from the mushroom Cryptoporus volvatus inhibits porcine reproductive and respiratory syndrome virus (PRRSV) in vitro |
| Q37985660 | A pharmacognostic approach to the Polygala genus: phytochemical and pharmacological aspects |
| Q90345842 | A review on anti-bacterials to combat resistance: From ancient era of plants and metals to present and future perspectives of green nano technological combinations |
| Q96816595 | A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors |
| Q55279851 | A systematic approach to identify therapeutic effects of natural products based on human metabolite information. |
| Q35121118 | A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity |
| Q27902298 | Accurate and efficient target prediction using a potency-sensitive influence-relevance voter |
| Q64063270 | Actinobacteria Isolated From : A Source of New Bioactive Compounds |
| Q34187311 | Activity and interactions of antibiotic and phytochemical combinations against Pseudomonas aeruginosa in vitro. |
| Q54340070 | Acute toxicity evaluation, antibacterial, antioxidant and immunomodulatory effects of Melastoma malabathricum. |
| Q39143318 | Addressing Facts and Gaps in the Phenolics Chemistry of Winery By-Products. |
| Q38992533 | Advances in venomics |
| Q28534724 | AfroDb: a select highly potent and diverse natural product library from African medicinal plants |
| Q99731894 | Aloe extract inhibits porcine epidemic diarrhea virus in vitro and in vivo |
| Q47424759 | Analysing and Navigating Natural Products Space for Generating Small, Diverse, But Representative Chemical Libraries |
| Q35745479 | Anchor-based classification and type-C inhibitors for tyrosine kinases |
| Q46473295 | Anthelmintic potential of three plants used in Nigerian ethnoveterinary medicine |
| Q28551486 | Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells |
| Q35207160 | Anti-inflammatory potential of zootherapeutics derived from animals used in Brazilian traditional medicine |
| Q36555983 | Anti-inflammatory, Anti-estrogenic, and Anti-implantation Activity of Bergia suffruticosa (Delile) Fenzl |
| Q55544709 | Anti-proliferative Effect of 15,16-Dihydrotanshinone I Through Cell Cycle Arrest and the Regulation of AMP-activated Protein Kinase/Akt/mTOR and Mitogen-activated Protein Kinase Signaling Pathway in Human Hepatocellular Carcinoma Cells. |
| Q64228461 | Antibacterial and cytotoxic activities of the leaf extract from Malaysia |
| Q27027984 | Antibiotic alternatives: the substitution of antibiotics in animal husbandry? |
| Q46580614 | Anticancer activity of five forest crops used in African folklore: antiproliferative and pro-apoptotic effects |
| Q33912677 | Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis. |
| Q47580171 | Antidiabetic, antioxidant, and TNF-α lowering properties of extract of the traditionally used plant Ixeris gracilis in alloxan-induced diabetic mice |
| Q40471718 | Antimicrobial activity of Alcaligenes sp. HPC 1271 against multidrug resistant bacteria. |
| Q48226991 | Antimicrobial synergism and cytotoxic properties of Citrus limon L., Piper nigrum L. and Melaleuca alternifolia (Maiden and Betche) Cheel essential oils. |
| Q44684847 | Antinociceptive effect of 7-methoxyflavone isolated from Zornia brasiliensis |
| Q33825850 | Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment. |
| Q36269003 | Antiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids |
| Q64080022 | Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation |
| Q41914878 | Antiproliferative activity of hamigerone and radicinol isolated from Bipolaris papendorfii |
| Q39066878 | Antiproliferative and antimicrobial activities of alkylbenzoquinone derivatives from Ardisia kivuensis |
| Q35002186 | Antiproliferative effects of cucurbitacin B in breast cancer cells: down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle |
| Q90720964 | Antithrombotic Effects of Paeoniflorin from Paeonia suffruticosa by Selective Inhibition on Shear Stress-Induced Platelet Aggregation |
| Q50246552 | Antituberculosis agent diaportheone B: synthesis, absolute configuration assignment, and anti-TB activity of its analogues. |
| Q41958276 | Antitussive Activity of the Water-Extracted Carbohydrate Polymer from Terminalia chebula on Citric Acid-Induced Cough. |
| Q93081014 | Antitussive and Anti-inflammatory Dual-active Agents Developed from Natural Product Lead Compound 1-Methylhydantoin |
| Q113697601 | Antiviral activity of Myracrodruon urundeuva against rotavirus |
| Q39348896 | Applicability of plant-based products in the treatment of Trypanosoma cruzi and Trypanosoma brucei infections: a systematic review of preclinical in vivo evidence. |
| Q39311040 | Application of Combination High-Throughput Phenotypic Screening and Target Identification Methods for the Discovery of Natural Product-Based Combination Drugs |
| Q57492942 | Applying an Ethical Framework to Herbal Medicine |
| Q48708365 | Approaches for discovering novel bioactive small molecules targeting autophagy. |
| Q52571462 | Aqueous Extract of Black Maca Prevents Metabolism Disorder via Regulating the Glycolysis/Gluconeogenesis-TCA Cycle and PPARα Signaling Activation in Golden Hamsters Fed a High-Fat, High-Fructose Diet. |
| Q58862110 | Assessing the pharmacokinetic profile of the CamMedNP natural products database: an in silico approach |
| Q36652416 | Assessment of biological activity and UPLC-MS based chromatographic profiling of ethanolic extract of Ochradenus arabicus. |
| Q55244362 | Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities. |
| Q31150361 | Attenuating effect of standardized fruit extract of Punica granatum L in rat model of tibial and sural nerve transection induced neuropathic pain |
| Q57059036 | Aurantoside C Targets and Induces Apoptosis in Triple Negative Breast Cancer Cells |
| Q33541158 | Automated high-throughput system to fractionate plant natural products for drug discovery |
| Q28079729 | Axonal Transport and Neurodegeneration: How Marine Drugs Can Be Used for the Development of Therapeutics |
| Q53059663 | Baceridin, a cyclic hexapeptide from an epiphytic bacillus strain, inhibits the proteasome. |
| Q36088201 | Back to the Roots: Prediction of Biologically Active Natural Products from Ayurveda Traditional Medicine |
| Q59129186 | Baicalin, the major component of traditional Chinese medicine Scutellaria baicalensis induces colon cancer cell apoptosis through inhibition of oncomiRNAs |
| Q36711252 | Benzoquinones and terphenyl compounds as phosphodiesterase-4B inhibitors from a fungus of the order Chaetothyriales (MSX 47445). |
| Q39824380 | Bingchamides A and B, two novel cyclic pentapeptides from the Streptomyces bingchenggensis: fermentation, isolation, structure elucidation and biological properties |
| Q34553685 | BioSM: metabolomics tool for identifying endogenous mammalian biochemical structures in chemical structure space |
| Q60960094 | Bioactivities of EF24, a Novel Curcumin Analog: A Review |
| Q41958943 | Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine Semen Persicae extract |
| Q39274695 | Bioassay-guided isolation and identification of cytotoxic compounds from Gymnosperma glutinosum leaves |
| Q57980490 | Biodiversity of benthic invertebrates and bioprospecting in Icelandic waters |
| Q30393596 | Biological Activities and Chemical Characterization of Cordia verbenacea DC. as Tool to Validate the Ethnobiological Usage |
| Q42132770 | Biological activities of extracts from Chenopodium ambrosioides Lineu and Kielmeyera neglecta Saddi |
| Q37308061 | CRIMALDDI: platform technologies and novel anti-malarial drug targets |
| Q37426159 | CVDHD: a cardiovascular disease herbal database for drug discovery and network pharmacology |
| Q30317837 | CamMedNP: building the Cameroonian 3D structural natural products database for virtual screening |
| Q38995716 | Cancer chemopreventive effects of the flavonoid-rich fraction isolated from papaya seeds. |
| Q92946963 | Cancer drug development: The missing links |
| Q95841072 | Cannabinomics: Application of Metabolomics in Cannabis (Cannabis sativa L.) Research and Development |
| Q38140631 | Catechin prodrugs and analogs: a new array of chemical entities with improved pharmacological and pharmacokinetic properties |
| Q36627842 | Cellular aggregation is a key parameter associated with long term variability in paclitaxel accumulation in Taxus suspension cultures |
| Q30431581 | Characterizing protein domain associations by Small-molecule ligand binding |
| Q33847870 | Chemical assay-guided natural product isolation via solid-supported chemodosimetric fluorescent probe. |
| Q36167128 | Cheminformatic comparison of approved drugs from natural product versus synthetic origins |
| Q36974459 | Chemistry and biology of kahalalides. |
| Q21089829 | Chemoinformatic analysis of GRAS (Generally Recognized as Safe) flavor chemicals and natural products |
| Q33420002 | Chemoinformatic analysis of combinatorial libraries, drugs, natural products, and molecular libraries small molecule repository |
| Q38830622 | Chinese herb medicine against Sortase A catalyzed transformations, a key role in gram-positive bacterial infection progress |
| Q28551786 | Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes |
| Q107038883 | Cognate and cognitive ecopharmacognosy — in an anthropogenic era |
| Q37939609 | Combinatorial biosynthesis in plants: a (p)review on its potential and future exploitation |
| Q91738562 | Comparative evaluation of antidiabetic potential of partially purified bioactive fractions from four medicinal plants in alloxan-induced diabetic rats |
| Q52649574 | Comparative modeling and virtual screening for the identification of novel inhibitors for myo-inositol-1-phosphate synthase. |
| Q46243466 | Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality |
| Q91749850 | Comprehensive mass spectrometry-guided phenotyping of plant specialized metabolites reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae |
| Q62020442 | Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae |
| Q57001336 | Computational Methodologies in the Exploration of Marine Natural Product Leads |
| Q58860055 | ConMedNP: a natural product library from Central African medicinal plants for drug discovery |
| Q47870186 | Core-structure-motivated design of iminium-enolate organocascade reactions: enantioselective syntheses of 5,6-dihydroindolizines |
| Q38843130 | Counting on natural products for drug design |
| Q34600066 | Cryptoporus volvatus extract inhibits influenza virus replication in vitro and in vivo |
| Q34737670 | Cryptoporus volvatus extract inhibits porcine reproductive and respiratory syndrome virus (PRRSV) in vitro and in vivo |
| Q21132294 | Crystal structure elucidation and anticancer studies of (-)-pseudosemiglabrin: a flavanone isolated from the aerial parts of Tephrosia apollinea |
| Q92134637 | Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics |
| Q41285029 | Cyclopropanations of olefin-containing natural products for simultaneous arming and structure activity studies |
| Q58213332 | Cytotoxic compounds from Laurencia pacifica |
| Q95819903 | Cytotoxic effect of selected wild orchids on two different human cancer cell lines |
| Q38699551 | Deoxyelephantopin and Isodeoxyelephantopin as Potential Anticancer Agents with Effects on Multiple Signaling Pathways. |
| Q40260500 | Design and development of some thiazole-based flavanoids as novel antibacterial against pathogens causing surgical site infection for possible benefit in bone trauma via inhibition of DNA gyrase. |
| Q38398596 | Design and synthesis of analogues of natural products |
| Q34197608 | Design and synthesis of screening libraries based on the muurolane natural product scaffold. |
| Q33880435 | Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo |
| Q30498042 | Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation--rationale, methods and preliminary results from a Sino-American collaboration |
| Q34565166 | Development of a Concise Synthetic Approach to Access Oroxin A. |
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| Q42555334 | Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells |
| Q39731165 | Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists. |
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| Q39081836 | Discovery of inhibitors of the Wnt and Hedgehog signaling pathways through the catalytic enantioselective synthesis of an iridoid-inspired compound collection |
| Q27006814 | Discovery of new anticancer agents from higher plants |
| Q34227609 | Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells |
| Q42705819 | Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network. |
| Q39861736 | Distinct biological network properties between the targets of natural products and disease genes |
| Q54284428 | Diversity and antagonistic potential of bacteria isolated from marine grass Halodule uninervis. |
| Q91619681 | Diversity of Streptomyces spp. from mangrove forest of Sarawak (Malaysia) and screening of their antioxidant and cytotoxic activities |
| Q56971083 | Diversity of the Mountain Flora of Central Asia with Emphasis on Alkaloid-Producing Plants |
| Q91707704 | Diversity, Ecology, and Prevalence of Antimicrobials in Nature |
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| Q53731399 | Drug design based on pentaerythritol tetranitrate reductase: synthesis and antibacterial activity of Pogostone derivatives. |
| Q30866998 | Drug discovery and natural products: end of an era or an endless frontier? |
| Q36275149 | Drug discovery from plant sources: An integrated approach |
| Q26749192 | Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project |
| Q51175842 | Dual substrate-controlled kinase activity leads to polyphosphorylated lasso peptides. |
| Q42343317 | Editorial for Special Issue on Herbal Medicines and Natural Products |
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| Q46488240 | Effect of methanol extract of Trigonella foenum-graecum L. seeds on anxiety, sedation and motor coordination |
| Q38921495 | Effect of the coffee ingredient cafestol on head and neck squamous cell carcinoma cell lines |
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| Q42219902 | Effects of veraguensin and galgravin on osteoclast differentiation and function |
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| Q39048482 | Emerging biopharmaceuticals from bioactive peptides derived from marine organisms |
| Q39123543 | Endophyte bioprospecting in South Asian medicinal plants: an attractive resource for biopharmaceuticals |
| Q91434236 | Engineering Saccharomyces cerevisiae for production of simvastatin |
| Q37072977 | Engineering biosynthesis of the anticancer alkaloid noscapine in yeast |
| Q42553360 | Enhanced inhibitory effect of curcumin via reactive oxygen species generation in human nasopharyngeal carcinoma cells following purple-light irradiation |
| Q34361613 | Enhancement of pheochromocytoma nerve cell growth by consecutive fractionization of Angelica gigas Nakai extracts |
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| Q45270728 | Evidence for the involvement of spinal cord-inhibitory and cytokines-modulatory mechanisms in the anti-hyperalgesic effect of hecogenin acetate, a steroidal sapogenin-acetylated, in mice. |
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| Q35556159 | Exploring new pharmacology and toxicological screening and safety evaluation of one widely used formulation of Nidrakar Bati from South Asia region |
| Q91405328 | Exploring novel secondary metabolites from natural products using pre-processed mass spectral data |
| Q36236997 | Extracting the Benefit of Nexrutine® for Cancer Prevention |
| Q47166014 | Field sampling marine plankton for biodiscovery. |
| Q34646772 | Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it. |
| Q46606929 | Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway |
| Q38941759 | Fisetin induces apoptosis in human nonsmall lung cancer cells via a mitochondria-mediated pathway |
| Q59336682 | Flexible docking-based molecular dynamics simulation of natural product compounds and Ebola virus Nucleocapsid (EBOV NP): a computational approach to discover new drug for combating Ebola |
| Q38313410 | From natural product-inspired pyrrolidine scaffolds to the development of new human Golgi α-mannosidase II inhibitors |
| Q27026070 | Functional augmentation of naturally-derived materials for tissue regeneration |
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| Q34265373 | Galangin induces apoptosis in hepatocellular carcinoma cells through the caspase 8/t-Bid mitochondrial pathway |
| Q38727626 | Genetic regulation and manipulation for natural product discovery |
| Q36676569 | Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM) |
| Q57139127 | Glycyrrhizic acid from licorice down-regulates inflammatory responses blocking MAPK and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation |
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| Q35033255 | Growth-Inhibitory and Apoptosis-Inducing Effects of Punica granatum L. var. spinosa (Apple Punice) on Fibrosarcoma Cell Lines |
| Q34307956 | Guiding principles for natural product drug discovery |
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| Q47626065 | Harnessing the potential of natural products in drug discovery from a cheminformatics vantage point |
| Q57251693 | Healing with animals in a semiarid northeastern area of Brazil |
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| Q36376309 | Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products |
| Q39664659 | Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products |
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| Q58860057 | How “drug-like” are naturally occurring anti-cancer compounds? |
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| Q35548806 | Identification and bioactivity of compounds from the fungus Penicillium sp. CYE-87 isolated from a marine tunicate |
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| Q36376809 | Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia |
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| Q91722985 | Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent |
| Q28477268 | Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays |
| Q38637840 | Immunomodulatory Effects of Taiwanese Neolitsea Species on Th1 and Th2 Functionality. |
| Q38856263 | Improving combination antiretroviral therapy by targeting HIV-1 gene transcription. |
| Q34358658 | In silico discovery of potential VEGFR-2 inhibitors from natural derivatives for anti-angiogenesis therapy. |
| Q30317914 | In silico drug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin. |
| Q42325997 | In vitro Antiproliferative and Apoptosis Inducing Effect of Allium atroviolaceum Bulb Extract on Breast, Cervical, and Liver Cancer Cells |
| Q91899839 | In vitro and in vivo Antidiabetic Properties of Phenolic Antioxidants From Sedum adenotrichum |
| Q28476407 | In vitro and in vivo anti-inflammatory activity of 17-O-acetylacuminolide through the inhibition of cytokines, NF-κB translocation and IKKβ activity |
| Q34218587 | In vitro cytotoxicity of Strobilanthes crispus ethanol extract on hormone dependent human breast adenocarcinoma MCF-7 cell. |
| Q56920710 | In vitro evaluation of antiprotozoal and antiviral activities of extracts from Argentinean Mikania species |
| Q37682061 | In-Vitro and in-Silico characterization of Sophora interrupta plant extract as an anticancer activity |
| Q36194385 | Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola |
| Q28821840 | Influence of Extracting Solvent on Pharmacological Activity and Cytotoxicity of Polygonum minus, a Commonly Consumed Herb in Southeast Asia |
| Q64078667 | Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives |
| Q38727093 | Inhibition of IKKβ by celastrol and its analogues - an in silico and in vitro approach |
| Q38370578 | Inhibition of growth of highly resistant bacterial and fungal pathogens by a natural product. |
| Q39570128 | Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source |
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| Q28488352 | Integration of Microfractionation, qNMR and zebrafish screening for the in vivo bioassay-guided isolation and quantitative bioactivity analysis of natural products |
| Q48930178 | Integration of Multiple Analytical and Computational Tools for the Discovery of High-Potency Enzyme Inhibitors from Herbal Medicines. |
| Q41857580 | Investigating Apoptotic Effects of Methanolic Extract of Dorema glabrum Seed on WEHI-164 Cells |
| Q57466159 | Investigating the potential use of an Antarctic variant of Janthinobacterium lividum for tackling antimicrobial resistance in a One Health approach |
| Q37998135 | Ion channel drug discovery: challenges and future directions |
| Q39869217 | Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation. |
| Q46985436 | Isolation and partial characterization of bacteria (Pseudoalteromonas sp.) with potential antibacterial activity from a marine costal environment from New Caledonia |
| Q51408607 | Isolation, structural assignment and synthesis of (SE)-2-methyloctyl 3-(4-methoxyphenyl) propenoate from the marine soft coral Sarcophyton ehrenbergi. |
| Q41550866 | Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis |
| Q92973713 | KRAS Binders Hidden in Nature |
| Q34631578 | Library construction and biological evaluation of enmein-type diterpenoid analogues as potential anticancer agents |
| Q57476633 | Licochalcone H induces the apoptosis of human oral squamous cell carcinoma cells via regulation of matrin 3 |
| Q37711622 | Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations |
| Q34555247 | Ligand fishing with functionalized magnetic nanoparticles coupled with mass spectrometry for herbal medicine analysis: ligand fishing for herbal medicine analysis |
| Q35214666 | Ligustrazinyl amides: a novel class of ligustrazine-phenolic acid derivatives with neuroprotective effects |
| Q37871597 | Low molecular weight inhibitors of Prolyl Oligopeptidase: a review of compounds patented from 2003 to 2010. |
| Q39343028 | MPD3: a useful medicinal plants database for drug designing |
| Q38031632 | Macrocycles in new drug discovery |
| Q38525246 | Management of diabetic complications through fruit flavonoids as a natural remedy |
| Q37727721 | Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation |
| Q37733538 | Marrubium vulgare L. methanolic extract inhibits inflammatory response and prevents cardiomyocyte fibrosis in isoproterenol-induced acute myocardial infarction in rats |
| Q41908389 | Merging allosteric and active site binding motifs: de novo generation of target selectivity and potency via natural-product-derived fragments. |
| Q55382745 | Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes. |
| Q33829836 | Metabolic engineering for the production of natural products. |
| Q38268052 | Metabolic isoenzyme shifts in cancer as potential novel therapeutic targets. |
| Q51144149 | Metabolomic approach for a rapid identification of natural products with cytotoxic activity against human colorectal cancer cells. |
| Q42326144 | Methods to optimize myxobacterial fermentations using off-gas analysis |
| Q36693987 | Micheliolide inhibits LPS-induced inflammatory response and protects mice from LPS challenge |
| Q37625743 | Micheliolide provides protection of mice against Staphylococcus aureus and MRSA infection by down-regulating inflammatory response |
| Q38914630 | Mimicking Peptides… In Silico |
| Q29353836 | Modern natural products drug discovery and its relevance to biodiversity conservation |
| Q30570945 | Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives |
| Q93126855 | Molecular Docking: Shifting Paradigms in Drug Discovery |
| Q58862097 | Molecular modeling of plant metabolites with anti-Onchocerca activity |
| Q47615282 | Molecular modeling of potential anticancer agents from African medicinal plants |
| Q34365901 | Molecular scaffold analysis of natural products databases in the public domain |
| Q42716635 | Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. |
| Q28480888 | Multi-target drugs: the trend of drug research and development |
| Q38502737 | Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside? |
| Q62496001 | Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery |
| Q26779924 | Natural Products: Insights into Leishmaniasis Inflammatory Response |
| Q38208376 | Natural compounds as next-generation herbicides |
| Q34948729 | Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia? |
| Q35844669 | Natural products and drug discovery: a survey of stakeholders in industry and academia |
| Q44322413 | Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach |
| Q38334179 | Natural products as leads in schistosome drug discovery. |
| Q37849845 | Natural products for cancer chemotherapy |
| Q57017619 | Natural products from Brazilian biodiversity as a source of new models for medicinal chemistry |
| Q35251525 | Natural products from ethnodirected studies: revisiting the ethnobiology of the zombie poison |
| Q38510631 | Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products |
| Q36245161 | Network pharmacology-based virtual screening of natural products from Clerodendrum species for identification of novel anti-cancer therapeutics. |
| Q28535324 | New antimalarial hits from Dacryodes edulis (Burseraceae)--part I: isolation, in vitro activity, in silico "drug-likeness" and pharmacokinetic profiles |
| Q34167537 | Nitroso Diels-Alder (NDA) reaction as an efficient tool for the functionalization of diene-containing natural products |
| Q42753230 | Nocapyrones: α- and γ-pyrones from a marine-derived Nocardiopsis sp. |
| Q38560455 | Non-clinical toxicity studies on bioactive compounds within the framework of nutritional and health claims |
| Q37699218 | Nordihydroguaiaretic acid impairs prostate cancer cell migration and tumor metastasis by suppressing neuropilin 1. |
| Q62364083 | Novel Types of Hypermodified Fluorescent Phyllobilins from Breakdown of Chlorophyll in Senescent Leaves of Grapevine (Vitis vinifera) |
| Q30488200 | Novel chemical space exploration via natural products |
| Q35907038 | Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells |
| Q42249570 | Novel phytochemical-antibiotic conjugates as multitarget inhibitors of Pseudomononas aeruginosa GyrB/ParE and DHFR. |
| Q38231113 | Nutraceuticals in lipid-lowering treatment: a narrative review on the role of chitosan. |
| Q30487721 | Open-access metabolomics databases for natural product research: present capabilities and future potential. |
| Q38637309 | PDTCM: a systems pharmacology platform of traditional Chinese medicine for psoriasis |
| Q53507294 | Pain Modulation by Lignans (Phyllanthin and Hypophyllanthin) and Tannin (Corilagin) Rich Extracts of Phyllanthus amarus in Carrageenan-induced Thermal and Mechanical Chronic Muscle Hyperalgesia. |
| Q21146447 | Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B. |
| Q35248674 | Pharmacoinformatics approach for investigation of alternative potential hepatitis C virus nonstructural protein 5B inhibitors. |
| Q46749346 | Phylogenetic exploration of commonly used medicinal plants in South Africa |
| Q42066799 | Phylogenetic identification of fungi isolated from the marine sponge Tethya aurantium and identification of their secondary metabolites |
| Q34415770 | Phylogenies reveal predictive power of traditional medicine in bioprospecting |
| Q44209042 | Physicochemical characterization of phyllanthin from Phyllanthus amarus Schum. et Thonn |
| Q37455520 | Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms. |
| Q86199455 | Phytomedicines as potential inhibitors of β amyloid aggregation: significance to Alzheimer's disease |
| Q41860086 | Pinocembrin: a novel natural compound with versatile pharmacological and biological activities |
| Q51800931 | Plant-Derived Natural Products for Parkinson's Disease Therapy. |
| Q34287501 | Plants as sources of new antimicrobials and resistance-modifying agents |
| Q41622472 | Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms |
| Q41129816 | Poly[3-(3, 4-dihydroxyphenyl) glyceric acid] from Comfrey exerts anti-cancer efficacy against human prostate cancer via targeting androgen receptor, cell cycle arrest and apoptosis |
| Q39188290 | Populene D analogues: design, concise synthesis and antiproliferative activity. |
| Q33942845 | Potential of plant-derived natural products in the treatment of leukemia and lymphoma |
| Q39615332 | Predicting the Presence of Uncommon Elements in Unknown Biomolecules from Isotope Patterns. |
| Q36086645 | Preliminary assessment of free radical scavenging, thrombolytic and membrane stabilizing capabilities of organic fractions of Callistemon citrinus (Curtis.) skeels leaves |
| Q33759695 | Preparation and biological evaluation of novel leucomycin analogs derived from nitroso Diels-Alder reactions |
| Q37109221 | Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin |
| Q36635534 | Pretreatment hepatoprotective effect of the marine fungus derived from sponge on hepatic toxicity induced by heavy metals in rats. |
| Q33695171 | Pretubulysin: a new option for the treatment of metastatic cancer |
| Q28483792 | Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy |
| Q54212465 | Profiling of red pigment produced by Streptomyces sp. JAR6 and its bioactivity. |
| Q89763469 | Proteome interrogation using gold nanoprobes to identify targets of arctigenin in fish parasites |
| Q34632201 | Proteomic analysis of polyketide and nonribosomal peptide biosynthesis |
| Q34880037 | Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections |
| Q39108134 | Quebrachitol: Global Status and Basic Research. |
| Q37271658 | Quinone derivatives isolated from the endolichenic fungus Phialocephala fortinii are Mdr1 modulators that combat azole resistance in Candida albicans |
| Q33706574 | Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position |
| Q58758818 | Raging the War Against Inflammation With Natural Products |
| Q47794007 | Rapid identification of α-glucosidase inhibitors from Dioscorea opposita Thunb peel extract by enzyme functionalized Fe3O4 magnetic nanoparticles coupled with HPLC-MS/MS. |
| Q34295223 | Rapid screening and identification of α-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR. |
| Q39055713 | Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin |
| Q47928337 | Relationship between Antioxidant and Anticancer Activity of Trihydroxyflavones. |
| Q34049007 | Repair and regeneration properties of Ginkgo biloba after ischemic brain injury |
| Q36691575 | Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis. |
| Q48251327 | Revealing the macromolecular targets of complex natural products |
| Q50281299 | Rewriting the Metabolic Blueprint: Advances in Pathway Diversification in Microorganisms. |
| Q33871943 | Role of natural product diversity in chemical biology |
| Q33553079 | Role of traditional Islamic and Arabic plants in cancer therapy |
| Q64902609 | S-ethyl ethanethiosulfinate, a derivative of allicin, induces metacaspase-dependent apoptosis through ROS generation in Penicillium chrysogenum. |
| Q38724403 | Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases |
| Q58691351 | Sanggenon C Stimulates Osteoblastic Proliferation and Differentiation, Inhibits Osteoclastic Resorption, and Ameliorates Prednisone-Induced Osteoporosis in Zebrafish Model |
| Q63353647 | Scaffold hopping from natural products to synthetic mimetics by holistic molecular similarity |
| Q33575779 | Screening a plant extract library for inhibitors of cholecystokinin receptor CCK1 pathways |
| Q50971734 | Screening bioactive compounds from Ligusticum chuanxiong by high density immobilized human umbilical vein endothelial cells. |
| Q34598999 | Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo |
| Q61806009 | Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro |
| Q36284748 | Sensitive quantification of coixol, a potent insulin secretagogue, in Scoparia dulcis extract using high-performance liquid chromatography combined with tandem mass spectrometry and UV detection. |
| Q30826246 | Separation of nine compounds from Salvia plebeia R.Br. using two-step high-speed counter-current chromatography with different elution modes. |
| Q34331288 | Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells |
| Q38083082 | Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 - 2012). |
| Q36999147 | Spasmolytic effect of caulerpine involves blockade of Ca²⁺ influx on guinea pig ileum |
| Q51036230 | Specific inhibition of hamster prion protein translocation by the dodecadepsipeptide valinomycin. |
| Q39008117 | Stelliosphaerols A and B, Sesquiterpene-Polyol Conjugates from an Ecuadorian Fungal Endophyte. |
| Q34616688 | Streamlining hit discovery and optimization with a yoctoliter scale DNA reactor |
| Q64092943 | Streptomyces monashensis sp. nov., a novel mangrove soil actinobacterium from East Malaysia with antioxidative potential |
| Q33457947 | Structure-oriented UHPLC-LTQ Orbitrap-based approach as a dereplication strategy for the identification of isoflavonoids from Amphimas pterocarpoides crude extract |
| Q38256051 | Structure–activity relationship of terpenes with anti-inflammatory profile – a systematic review |
| Q51369692 | Subchronic toxicity study of the total flavonoids from Rosa laevigata Michx fruit in rats. |
| Q91791781 | Synergistic effect of tolfenamic acid and glycyrrhizic acid on TPA-induced skin inflammation in mice |
| Q64067996 | Synergistic effects of deuterium depleted water and Mentha longifolia L. essential oils on sepsis-induced liver injuries through regulation of cyclooxygenase-2 |
| Q38848194 | Synthesis and Antibacterial Evaluation of Novel 3-Substituted Ocotillol-Type Derivatives as Leads. |
| Q46331355 | Synthesis and Biological Evaluation of Paclitaxel and Camptothecin Prodrugs on the Basis of 2-Nitroimidazole. |
| Q38741456 | Synthesis and Characterization of Sygyzium cumini Nanoparticles for Its Protective Potential in High Glucose-Induced Cardiac Stress: a Green Approach. |
| Q28834091 | Synthesis and Evaluation of a 2,11-Cembranoid-Inspired Library |
| Q38012033 | Synthesis and bioactivity of secondary metabolites from marine sponges containing dibrominated indolic systems. |
| Q34089945 | Synthesis and evaluation of macrocyclic diarylether heptanoid natural products and their analogs |
| Q87633508 | Synthesis and pharmacological evaluation of carvacrol propionate |
| Q28828453 | Synthesis, Biological Activity, and Apoptotic Properties of NO-Donor/Enmein-Type ent-Kauranoid Hybrids |
| Q37993068 | Synthetic strategies to terpene quinones/hydroquinones |
| Q89526241 | Targeted Covalent Inhibition of Telomerase |
| Q35273449 | Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget |
| Q35830892 | Targeting metabolic disorders by natural products |
| Q33915473 | Targeting oncogenic protein-protein interactions by diversity oriented synthesis and combinatorial chemistry approaches. |
| Q38175450 | Terpenes and derivatives as a new perspective for pain treatment: a patent review |
| Q37680690 | Terpenyl-purines from the sea. |
| Q34121811 | Tetramethoxychalcone, a chalcone derivative, suppresses proliferation, blocks cell cycle progression, and induces apoptosis of human ovarian cancer cells |
| Q39535327 | The Acid/Base Profile of the Human Metabolome and Natural Products |
| Q38803944 | The Antibiotic Resistant Target Seeker (ARTS), an exploration engine for antibiotic cluster prioritization and novel drug target discovery |
| Q91961715 | The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds |
| Q33850210 | The Chinese medicine, Jianpi Huayu Decoction, inhibits the epithelial mesenchymal transition via the regulation of the Smad3/Smad7 cascade |
| Q109970201 | The Value of Digitising Natural History Collections |
| Q89540134 | The X-factor: Enhanced β-oxidation on intracellular triacylglycerols enabling overproduction of polyketide drug-like molecules in microorganisms |
| Q34849136 | The anti-cancer property of proteins extracted from Gynura procumbens (Lour.) Merr |
| Q38061445 | The application of Chinese medicine to novel drug discovery |
| Q33717343 | The continuing search for antitumor agents from higher plants |
| Q34879391 | The identification of naturally occurring neoruscogenin as a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1). |
| Q34147144 | The impact of plant-pathogen studies on medicinal drug discovery. |
| Q89002951 | The natural product chitosan enhances the anti-tumor activity of natural killer cells by activating dendritic cells |
| Q34171983 | The natural product phyllanthusmin C enhances IFN-γ production by human NK cells through upregulation of TLR-mediated NF-κB signaling |
| Q90291678 | The perceptions of natural compounds against dipeptidyl peptidase 4 in diabetes: from in silico to in vivo |
| Q58856029 | The pharmaceutical industry and natural products: historical status and new trends |
| Q26824879 | The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids |
| Q34459318 | The re-emergence of natural products for drug discovery in the genomics era. |
| Q39050184 | The structural modification of natural products for novel drug discovery |
| Q58860062 | The uniqueness and therapeutic value of natural products from West African medicinal plants, part II: terpenoids, geographical distribution and drug discovery |
| Q35219974 | Total synthesis and biological evaluation of tyroscherin |
| Q33717398 | Transitioning pharmacoperones to therapeutic use: in vivo proof-of-principle and design of high throughput screens. |
| Q34140687 | Trends in the discovery of new marine natural products from invertebrates over the last two decades--where and what are we bioprospecting? |
| Q39911727 | Two new asterriquinols from Aspergillus sp. CBS-P-2 with anti-inflammatory activity |
| Q34218411 | Universal quantification of structurally diverse natural products using an evaporative light scattering detector |
| Q89944007 | Unripe Rubus coreanus Miquel Extract Containing Ellagic Acid Regulates AMPK, SREBP-2, HMGCR, and INSIG-1 Signaling and Cholesterol Metabolism In Vitro and In Vivo |
| Q39388546 | Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016). |
| Q38988001 | Use of Cymbopogon citratus essential oil in food preservation: Recent advances and future perspectives |
| Q38092741 | Use of in situ solid-phase adsorption in microbial natural product fermentation development |
| Q28487019 | Use of natural products as chemical library for drug discovery and network pharmacology |
| Q42279211 | Using reverse docking to identify potential targets for ginsenosides. |
| Q52361555 | Venomics-Accelerated Cone Snail Venom Peptide Discovery. |
| Q57946310 | Venomics: A Mini-Review |
| Q57161193 | Virtual Screening and Biomolecular Interactions of CviR-Based Quorum Sensing Inhibitors Against |
| Q36307943 | Virtual screening of natural compounds as inhibitors of EGFR 696-1022 T790M associated with non-small cell lung cancer |
| Q28278411 | Virtual screening: an endless staircase? |
| Q28540495 | Virtualizing the p-ANAPL library: a step towards drug discovery from African medicinal plants |
| Q92445579 | Zebrafish as an Emerging Model for Bioassay-Guided Natural Product Drug Discovery for Neurological Disorders |
| Q30397301 | Zootherapeutics utilized by residents of the community Poço Dantas, Crato-CE, Brazil |
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