A phase I study of bendamustine hydrochloride administered day 1+2 every 3 weeks in patients with solid tumours

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A phase I study of bendamustine hydrochloride administered day 1+2 every 3 weeks in patients with solid tumours is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1018709933
P356DOI10.1038/SJ.BJC.6603776
P932PMC publication ID2359912
P698PubMed publication ID17486132
P5875ResearchGate publication ID6345535

P2093author name stringJ B Vermorken
J Dyck
D Schrijvers
J Van den Brande
J Bosmans
M Rasschaert
K Merkle
P2860cites workBendamustine is effective in relapsed or refractory aggressive non-Hodgkin's lymphomaQ33343780
Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphomaQ33366403
Phase II trial of second-line bendamustine chemotherapy in relapsed small cell lung cancer patientsQ33373244
A phase I study of bendamustine hydrochloride administered once every 3 weeks in patients with solid tumorsQ33374826
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Bendamustine hydrochloride activity against doxorubicin-resistant human breast carcinoma cell lines.Q34734956
Metabolism and mechanisms of action of bendamustine: rationales for combination therapiesQ34778774
Phase I studies with bendamustine: an updateQ34778779
The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial functionQ36211375
Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochlorideQ40234705
Weekly administration of bendamustine: a phase I study in patients with advanced progressive solid tumoursQ40616659
Repeated administration of short infusions of bendamustine: a phase I study in patients with advanced progressive solid tumoursQ40627330
In vitro induction of apoptosis of neoplastic cells in low-grade non-Hodgkin's lymphomas using combinations of established cytotoxic drugs with bendamustineQ40701958
Bendamustine as salvage treatment in patients with advanced progressive breast cancer: a phase II studyQ40831325
Toxicity of the alkylating agent bendamustinQ42224728
Cytotoxic efficacy of bendamustine in human leukemia and breast cancer cell linesQ44005427
In vitro evaluation of bendamustine induced apoptosis in B-chronic lymphocytic leukemiaQ44161643
High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomasQ44233737
Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase actiQ44569025
Bendamustine, vincristine and prednisone (BOP) versus cyclophosphamide, vincristine and prednisone (COP) in advanced indolent non-Hodgkin's lymphoma and mantle cell lymphoma: results of a randomised phase III trial (OSHO# 19).Q44966920
Synthesis and characterization of some new phase II metabolites of the alkylator bendamustine and their identification in human bile, urine, and plasma from patients with cholangiocarcinomaQ46450156
Treatment of bendamustine and prednisone in patients with newly diagnosed multiple myeloma results in superior complete response rate, prolonged time to treatment failure and improved quality of life compared to treatment with melphalan and prednisoQ46886613
Regression of brain metastases from breast carcinoma after chemotherapy with bendamustineQ48679005
Selective uptake of the anticancer drug bendamustine by liver and kidney tissues following its intravenous administration to mice.Q49088927
Phase-I/II study to evaluate dose limiting toxicity, maximum tolerated dose, and tolerability of bendamustine HCl in pre-treated patients with B-chronic lymphocytic leukaemia (Binet stages B and C) requiring therapy.Q51831972
Efficacy and toxicity of bendamustine in patients with relapsed low-grade non-Hodgkin's lymphomas.Q53991694
Aminos�ureantagonisten. III. ?-[Bis-(?-chlor�thyl)-amino-benzimidazolyl-(2)]-propion- bzw. -butters�uren als potentielle CytostatikaQ57075378
[Pharmacokinetics of bendamustin (Cytostasan) in B6D2F1-mice]Q67870047
Hepatobiliary elimination of bendamustin (Cytostasan) in ratsQ67884893
[Chemotherapy of advanced non-small-cell and small-cell bronchial carcinoma with bendamustine--a phase II study]Q77662037
Bendamustine prolongs progression-free survival in metastatic breast cancer (MBC): a phase III prospective, randomized, multicenter trial of bendamustine hydrochloride, methotrexate and 5-fluorouracil (BMF) versus cyclophosphamide, methotrexate andQ81050174
Efficacy of bendamustine in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase I/II study of the German CLL Study GroupQ81340591
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectbendamustineQ425745
P304page(s)1692-1698
P577publication date2007-05-08
P1433published inBritish Journal of CancerQ326309
P1476titleA phase I study of bendamustine hydrochloride administered day 1+2 every 3 weeks in patients with solid tumours
P478volume96