Effects of phosphodiesterase 4 inhibition on alveolarization and hyperoxia toxicity in newborn rats

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Effects of phosphodiesterase 4 inhibition on alveolarization and hyperoxia toxicity in newborn rats is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2008PLoSO...3.3445M
P356DOI10.1371/JOURNAL.PONE.0003445
P932PMC publication ID2563688
P698PubMed publication ID18941502
P5875ResearchGate publication ID23403296

P50authorCéline MéhatsQ55875767
P2093author name stringThomas Schmitz
Christophe Delacourt
Danièle Evain-Brion
Olivier Boucherat
Pierre-Henri Jarreau
Emmanuel Lopez
Marie-Laure Franco-Montoya
Elodie Zana
Jacques Bourbon
P2860cites workInfluence of selective phosphodiesterase inhibitors on human neutrophil functions and levels of cAMP and Cai.Q44524786
Pentoxifylline reduces fibrin deposition and prolongs survival in neonatal hyperoxic lung injuryQ44945408
Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brainQ46080598
Relationship between neonatal leukemoid reaction and bronchopulmonary dysplasia in low-birth-weight infants: a cross-sectional studyQ47175290
Outcome of extremely low birth weight infants with leukemoid reactionQ47379843
Upregulation of phosphodiesterase-4 in the lung of allergic ratsQ47861309
Gene expression profile and histopathology of experimental bronchopulmonary dysplasia induced by prolonged oxidative stressQ48024586
Characterization of cyclic nucleotide phosphodiesterases of rat tissuesQ48824116
Antimacrophage chemokine treatment prevents neutrophil and macrophage influx in hyperoxia-exposed newborn rat lung.Q51685958
Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction.Q53576295
PDE4 inhibition prevents preterm delivery induced by an intrauterine inflammation.Q54449137
Effect of intratracheal adenoviral vector administration on lung development in newborn ratsQ64378371
Effects of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burstQ68160262
The postnatal development and growth of the human lung. I. MorphometryQ69003350
The toxicity of repeated exposures to rolipram, a type IV phosphodiesterase inhibitor, in ratsQ71203407
Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding siteQ72335344
Pentoxifylline does not protect against hyperoxic lung injury in ratsQ72798459
Lung inflammation in hyperoxia can be prevented by antichemokine treatment in newborn ratsQ73286382
Hypoxic and hyperoxic effect on blood phosphodiesterase activity in young and old ratsQ77741773
Phosphodiesterase 4B2 is the predominant phosphodiesterase species and undergoes differential regulation of gene expression in human monocytes and neutrophilsQ77933655
Investigation of the molecular mechanisms preceding PDE4 inhibitor-induced vasculopathy in rats: tissue inhibitor of metalloproteinase 1, a potential predictive biomarkerQ80479749
Nitric oxide donor restores lung growth factor and receptor expression in hyperoxia-exposed rat pupsQ82582862
Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosisQ24817140
The human cyclic AMP-specific phosphodiesterase PDE-46 (HSPDE4A4B) expressed in transfected COS7 cells occurs as both particulate and cytosolic species that exhibit distinct kinetics of inhibition by the antidepressant rolipramQ28115926
Bronchopulmonary dysplasiaQ28237555
Cyclic nucleotide phosphodiesterases: molecular regulation to clinical useQ28263273
Gene expression profiling in lung fibroblasts reveals new players in alveolarizationQ28569682
Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient miceQ28594618
Role of osteopontin in cellular signaling and toxicant injuryQ28594622
Caffeine Therapy for Apnea of PrematurityQ29395883
Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responsesQ30732295
Amniotic fluid cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8) and the risk for the development of bronchopulmonary dysplasiaQ34446393
Postnatal development of alveoli. Regulation and evidence for a critical period in ratsQ34557173
Long-term effects of caffeine therapy for apnea of prematurityQ34711652
Phosphodiesterase-4 inhibition attenuates pulmonary inflammation in neonatal lung injuryQ34727917
Bronchopulmonary dysplasia-oxidative stress and antioxidantsQ35095604
Phosphodiesterase-4 inhibitors in the treatment of inflammatory lung disease.Q35592380
An update and appraisal of the cilomilast Phase III clinical development programme for chronic obstructive pulmonary diseaseQ35827644
Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasiaQ36092140
The radial alveolar count method of Emery and Mithal: a reappraisal 1--postnatal lung growthQ36122596
The radial alveolar count method of Emery and Mithal: a reappraisal 2--intrauterine and early postnatal lung growthQ36122656
Contribution of inflammation to lung injury and developmentQ36403068
Are phosphodiesterase 4 inhibitors just more theophylline?Q36496374
Chronic lung disease after premature birth.Q36995880
4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3',5'-monophosphate phosphodiesterases in homogenates and tissue slices from rat brainQ40035136
Phosphodiesterase isozymes: molecular targets for novel antiasthma agentsQ41708863
Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasiaQ41886471
The postnatal growth of the rat lung. I. MorphometryQ43589639
Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn ratsQ43660336
Interleukin-1beta induces phosphodiesterase 4B2 expression in human myometrial cells through a prostaglandin E2- and cyclic adenosine 3',5'-monophosphate-dependent pathwayQ44238617
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)e3445
P577publication date2008-10-20
P1433published inPLOS OneQ564954
P1476titleEffects of phosphodiesterase 4 inhibition on alveolarization and hyperoxia toxicity in newborn rats
P478volume3

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cites work (P2860)
Q35168732Caffeine and rolipram affect Smad signalling and TGF-β1 stimulated CTGF and transgelin expression in lung epithelial cells
Q96124116Commentary: Phosphodiesterase 4 inhibitors as potential adjunct treatment targeting the cytokine storm in COVID-19
Q36767721Development and assessment of countermeasure formulations for treatment of lung injury induced by chlorine inhalation
Q28579991Differential expression of cyclic nucleotide phosphodiesterases 4 in developing rat lung
Q27303463Effect of two models of intrauterine growth restriction on alveolarization in rat lungs: morphometric and gene expression analysis
Q43863162Inflammation and bronchopulmonary dysplasia
Q35950168Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats.
Q92610839Rolipram Protects Mice from Gram-negative Bacterium Escherichia coli-induced Inflammation and Septic Shock

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