New and emerging anticoagulant therapy for atrial fibrillation and acute coronary syndrome

scientific article

New and emerging anticoagulant therapy for atrial fibrillation and acute coronary syndrome is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1592/PHCO.31.10.975
P698PubMed publication ID21950643

P2093author name stringJennifer A Campbell
Kathleen A Packard
Estella M Davis
Jon T Knezevich
P2860cites workOral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of AZD0837 vs. vitamin K antagonistsQ24647947
Bivalirudin for patients with acute coronary syndromesQ28210982
An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigatorsQ28254763
Dabigatran versus warfarin in patients with atrial fibrillationQ28256895
New oral anticoagulants in atrial fibrillationQ28261825
2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on Dabigatran): a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelinesQ28305368
Oral rivaroxaban for symptomatic venous thromboembolismQ29620160
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trialQ34102430
Antithrombotic strategies in patients undergoing percutaneous coronary intervention for acute coronary syndromeQ34129340
Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trialQ34134664
Apixaban versus enoxaparin for thromboprophylaxis after hip replacementQ34156023
Apixaban in patients with atrial fibrillationQ34163710
Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct Factor Xa inhibitorQ34381344
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trialQ34607209
Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteersQ34615829
Rivaroxaban: a new oral factor Xa inhibitorQ34616521
Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rationale and design of the ROCKET AF studyQ34617523
Effects of food on the pharmacokinetics of edoxaban, an oral direct factor Xa inhibitor, in healthy volunteersQ34620374
Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In MyocardialQ34624280
Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).Q34788530
Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplastyQ34789112
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplastyQ34789118
Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trialQ34789474
Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in developmentQ34900298
Advancement in antithrombotics for stroke prevention in atrial fibrillationQ37143256
Rivaroxaban -- an oral, direct Factor Xa inhibitor: lessons from a broad clinical study programmeQ37383508
Newer anticoagulants in 2009.Q37617159
Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic reviewQ37661890
Novel oral anticoagulants for prophylaxis and treatment of venous thromboembolism: part I (Factor Xa inhibitors).Q37810274
Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developmentsQ37818783
New oral anticoagulantsQ37843749
Drug and dietary interactions of warfarin and novel oral anticoagulants: an updateQ37848142
Pharmacokinetics of otamixaban, a direct factor Xa inhibitor, in healthy male subjects: pharmacokinetic model development for phase 2/3 simulation of exposureQ40359866
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjectsQ41121441
Factors affecting adherence to guidelines for antithrombotic therapy in elderly patients with atrial fibrillation admitted to internal medicine wardsQ42791455
Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trialQ42830264
Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillationQ42839725
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).Q42923039
Synergistic effect of a factor Xa inhibitor, TAK-442, and antiplatelet agents on whole blood coagulation and arterial thrombosis in ratsQ43069087
Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationaleQ43138658
Prevention of venous thromboembolism with an oral factor Xa inhibitor, YM150, after total hip arthroplasty. A dose finding study (ONYX-2).Q43188583
In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studiesQ43235385
Apixaban: an emerging oral factor Xa inhibitorQ43240015
A cost-effectiveness model comparing rivaroxaban and dabigatran etexilate with enoxaparin sodium as thromboprophylaxis after total hip and total knee replacement in the irish healthcare settingQ43267101
The first evaluation of a novel vitamin K antagonist, tecarfarin (ATI-5923), in patients with atrial fibrillationQ43279486
Otamixaban for the treatment of patients with non-ST-elevation acute coronary syndromes (SEPIA-ACS1 TIMI 42): a randomised, double-blind, active-controlled, phase 2 trialQ43283673
Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trialQ44672192
Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial: study design and rationaleQ45137335
Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial.Q45962608
Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) trial.Q45995789
Rationale and design of RE-LY: randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatranQ46045990
Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging studyQ46550059
Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study).Q46939643
Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillationQ49811601
New oral anticoagulants in development.Q50276490
Cost-effectiveness of rivaroxaban versus enoxaparin for the prevention of postsurgical venous thromboembolism in CanadaQ53064705
The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement.Q53229008
Direct and rapid inhibition of factor Xa by otamixaban: a pharmacokinetic and pharmacodynamic investigation in patients with coronary artery disease.Q53244860
Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.Q54135542
Safety of edoxaban, an oral factor Xa inhibitor, in Asian patients with non-valvular atrial fibrillation.Q55053661
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectanticoagulantQ215118
acute coronary syndromeQ266018
atrial fibrillationQ815819
anticoagulationQ63279445
P304page(s)975-1016
P577publication date2011-10-01
P1433published inPharmacotherapyQ7180800
P1476titleNew and emerging anticoagulant therapy for atrial fibrillation and acute coronary syndrome
P478volume31

Reverse relations

cites work (P2860)
Q54561846Acute ischemic stroke following cardioversion in a patient receiving dabigatran.
Q36108384An evidence-based review of apixaban and its potential in the prevention of stroke in patients with atrial fibrillation
Q37590158Atrial fibrillation: mechanisms, therapeutics, and future directions
Q34993935Evaluating the efficacy and safety of apixaban, a new oral anticoagulant, using Bayesian meta-analysis
Q26996325High-maintenance-dose clopidogrel in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis
Q34670994Hypersensitivity reactions to modern antiplatelet and anticoagulant drugs
Q38038905New oral anticoagulants: a review of the literature with particular emphasis on patients with impaired renal function
Q38838530Novel Oral Anticoagulants in Atrial Fibrillation: Update on Apixaban.
Q38124014Optimizing the use of anticoagulants (heparins and oral anticoagulants) in the elderly
Q43594298Oral factor Xa inhibitors for the long-term management of ACS.
Q38163036Pharmacologic and nonpharmacologic thromboprophylactic strategies in atrial fibrillation
Q38033194Prevention of venous thromboembolism with new oral anticoagulants versus standard pharmacological treatment in acute medically ill patients: a systematic review and meta-analysis
Q38888217Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists, aspirin or direct acting oral anticoagulants

Search more.