scholarly article | Q13442814 |
P50 | author | Cesare Montecucco | Q504278 |
Mario Milco D'Elios | Q52868123 | ||
Daniel Ladant | Q56811517 | ||
P2093 | author name string | Marisa Benagiano | |
Cosima T Baldari | |||
Silvia Rossi Paccani | |||
Irene Zornetta | |||
Nagaja Capitani | |||
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The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18) | Q24675699 | ||
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
Anthrax toxin receptor 2-dependent lethal toxin killing in vivo | Q28572283 | ||
Functional diversity of helper T lymphocytes | Q29619415 | ||
Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP! | Q30439119 | ||
Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells. | Q30449654 | ||
Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases. | Q33380169 | ||
Lineage commitment in the immune system: the T helper lymphocyte grows up. | Q33970744 | ||
E-prostanoid (EP)2/EP4 receptor-dependent maturation of human monocyte-derived dendritic cells and induction of helper T2 polarization. | Q51051385 | ||
The p38 mitogen-activated protein kinase regulates effector functions of primary human CD4 T cells. | Q51987576 | ||
Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production. | Q52547955 | ||
The molecular machinery for cAMP-dependent immunomodulation in T-cells: Figure 1 | Q57371064 | ||
Defective immunoglobulin class switching in Vav-deficient mice is attributable to compromised T cell help | Q63408332 | ||
cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction | Q72403439 | ||
Cyclic AMP inhibits extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways by inhibiting Rap1 | Q74293069 | ||
Adjuvant and protective properties of native and recombinant Bordetella pertussis adenylate cyclase toxin preparations in mice | Q77391682 | ||
p38 alpha mitogen-activated protein kinase is activated by CD28-mediated signaling and is required for IL-4 production by human CD4+CD45RO+ T cells and Th2 effector cells | Q77841569 | ||
SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1 | Q80991137 | ||
Direct inhibition of T-lymphocyte activation by anthrax toxins in vivo | Q34194649 | ||
The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses | Q34448375 | ||
Pore formation by the Bordetella adenylate cyclase toxin in lipid bilayer membranes: role of voltage and pH. | Q34708490 | ||
Effect of different forms of adenylate cyclase toxin of Bordetella pertussis on protection afforded by an acellular pertussis vaccine in a murine model | Q35220336 | ||
Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice. | Q35848067 | ||
Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4 | Q36228702 | ||
Bordetella adenylate cyclase toxin: a swift saboteur of host defense | Q36365962 | ||
Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling | Q36403206 | ||
AKAP signaling complexes: getting to the heart of the matter | Q36523453 | ||
The molecular machinery for cAMP-dependent immunomodulation in T-cells | Q36541993 | ||
Anthrax toxin: receptor binding, internalization, pore formation, and translocation | Q36750138 | ||
Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death. | Q38323912 | ||
Insertional mutagenesis of Bordetella pertussis adenylate cyclase | Q38330594 | ||
Cell entry and cAMP imaging of anthrax edema toxin | Q39121575 | ||
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis | Q39758258 | ||
cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin | Q39939713 | ||
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. | Q40174738 | ||
Protein kinase A regulates GATA-3-dependent activation of IL-5 gene expression in Th2 cells | Q40665498 | ||
cAMP inhibition of Akt is mediated by activated and phosphorylated Rap1b | Q40721660 | ||
Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression | Q40843952 | ||
Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction | Q42047758 | ||
The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. | Q42906330 | ||
Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production | Q42942780 | ||
Cholera toxin indirectly activates human monocyte-derived dendritic cells in vitro through the production of soluble factors, including prostaglandin E(2) and nitric oxide. | Q43192962 | ||
Multiple signals required for cyclic AMP-responsive element binding protein (CREB) binding protein interaction induced by CD3/CD28 costimulation | Q43512765 | ||
Complement receptor 3 ligation of dendritic cells suppresses their stimulatory capacity | Q44240882 | ||
Prostaglandin E2 synthesis in human monocyte-derived dendritic cells | Q44469414 | ||
Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis. | Q44707224 | ||
Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells | Q44851086 | ||
Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax | Q45043237 | ||
TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling | Q45094763 | ||
Adjuvanticity of native and detoxified adenylate cyclase toxin of Bordetella pertussis towards co-administered antigens | Q45098739 | ||
Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling. | Q45129927 | ||
Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation. | Q45147807 | ||
Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein. | Q45253754 | ||
Evaluation of serologic tests for diagnosis of anthrax after an outbreak of cutaneous anthrax in Paraguay | Q45520319 | ||
Anthrax edema toxin cooperates with lethal toxin to impair cytokine secretion during infection of dendritic cells | Q46425895 | ||
Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells | Q46653871 | ||
Evidence for adjuvanticity of anthrax edema toxin | Q46707928 | ||
Bacillus anthracis edema toxin acts as an adjuvant for mucosal immune responses to nasally administered vaccine antigens | Q46902199 | ||
Bacterial toxins as mucosal adjuvants. | Q50127978 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageQuant | Q112270642 |
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Bordetella pertussis | Q137103 |
Bacillus anthracis | Q614156 | ||
P304 | page(s) | e1000325 | |
P577 | publication date | 2009-03-06 | |
P1433 | published in | PLOS Pathogens | Q283209 |
P1476 | title | The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling | |
P478 | volume | 5 |
Q37727941 | A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection |
Q54217728 | A bivalent protein r-PB, comprising PA and BclA immunodominant regions for comprehensive protection against Bacillus anthracis. |
Q41012029 | Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells. |
Q40064017 | Anthrax Vaccine Precipitated induces Edema Toxin-neutralizing, Edema Factor-specific antibodies in human recipients |
Q35161514 | Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity |
Q38060730 | Anthrax lethal toxin and the induction of CD4 T cell immunity |
Q27000357 | Bacillus anthracis edema factor substrate specificity: evidence for new modes of action |
Q90419622 | Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy |
Q35217146 | Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells. |
Q30360778 | Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3 |
Q34399010 | Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network |
Q34994573 | Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the entry route |
Q34807865 | Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain. |
Q27010363 | Cellular and physiological effects of anthrax exotoxin and its relevance to disease |
Q54979011 | Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes. |
Q64121539 | Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling |
Q50041452 | Elevated cyclic AMP Inhibits Mycobacterium tuberculosis-stimulated T cell IFN-γ Secretion through type I Protein Kinase A. |
Q35726627 | Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines |
Q37935265 | New insights into the biological effects of anthrax toxins: linking cellular to organismal responses |
Q41649263 | Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction |
Q28392599 | Passive Immunotherapy Protects against Enteric Invasion and Lethal Sepsis in a Murine Model of Gastrointestinal Anthrax |
Q24602050 | Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools |
Q30416562 | Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection |
Q30425735 | Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussis |
Q37954335 | T cell targeting by anthrax toxins: two faces of the same coin |
Q30301113 | The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies |
Q35213542 | The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse |
Q37955761 | The myriad roles of cyclic AMP in microbial pathogens: from signal to sword |
Q38129761 | The virulence factors of Bordetella pertussis: talented modulators of host immune response. |
Q36540595 | Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection |
Q37954284 | Toxins-useful biochemical tools for leukocyte research |
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