A Phase 1, Multi-Center, Open-Label, Dose-Escalation Study of 131I-CLR1404 in Subjects with Relapsed or Refractory Advanced Solid Malignancies

scientific article

A Phase 1, Multi-Center, Open-Label, Dose-Escalation Study of 131I-CLR1404 in Subjects with Relapsed or Refractory Advanced Solid Malignancies is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3109/07357907.2015.1081691
P698PubMed publication ID26536061

P50authorJoanne E MortimerQ56826504
P2093author name stringKatherine Oliver
Glenn Liu
Jennifer Heideman
Jamey Weichert
Michael Pishvaian
Scott Perlman
Lance Hall
Sam Joseph Lubner
Jacqueline Mullvain
P2860cites workFluorescent Cancer-Selective Alkylphosphocholine Analogs for Intraoperative Glioma DetectionQ27346925
Alpha emitter radium-223 and survival in metastatic prostate cancerQ29617472
Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy.Q30620931
Re-treatment with I-131 tositumomab in patients with non-Hodgkin's lymphoma who had previously responded to I-131 tositumomabQ33368796
Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analoguesQ33870440
Phospholipid ether analogs for the detection of colorectal tumorsQ34294317
Papillary thyroid carcinoma managed at the Mayo Clinic during six decades (1940-1999): temporal trends in initial therapy and long-term outcome in 2444 consecutively treated patientsQ34523261
A phase 1 study of 131I-CLR1404 in patients with relapsed or refractory advanced solid tumors: dosimetry, biodistribution, pharmacokinetics, and safetyQ34523934
Phase III trial of consolidation therapy with yttrium-90-ibritumomab tiuxetan compared with no additional therapy after first remission in advanced follicular lymphomaQ34598460
Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospectsQ34806351
Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agentsQ35088190
Developments in the internal dosimetry of radiopharmaceuticalsQ35550407
Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancerQ35855096
Lipid rafts and clusters of apoptotic signaling molecule-enriched rafts in cancer therapy.Q37750797
Bone-targeting radiopharmaceuticals including radium-223.Q38075735
A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cellsQ40093876
Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts.Q40227228
Synthesis and structure-activity relationship effects on the tumor avidity of radioiodinated phospholipid ether analoguesQ40298705
Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesisQ40710187
Edelfosine is incorporated into rafts and alters their organizationQ46422474
Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activationQ46472923
Physical models and dose factors for use in internal dose assessmentQ47666272
Perspectives of novel imaging techniques for staging, therapy response assessment, and monitoring of surveillance in lung cancer: summary of the Dresden 2013 Post WCLC-IASLC State-of-the-Art Imaging WorkshopQ48624737
Localized well-differentiated thyroid carcinoma: survival analysis of prognostic factors and (131)I therapy.Q50880255
131I-tositumomab therapy as initial treatment for follicular lymphoma.Q54682444
Effect of anti-tumor ether lipids on ordered domains in model membranesQ57360781
Cytotoxicity of an Anti-cancer Lysophospholipid through Selective Modification of Lipid Raft CompositionQ57372381
P433issue10
P304page(s)483-489
P577publication date2015-11-04
P1433published inCancer InvestigationQ325953
P1476titleA Phase 1, Multi-Center, Open-Label, Dose-Escalation Study of 131I-CLR1404 in Subjects with Relapsed or Refractory Advanced Solid Malignancies
P478volume33