| scholarly article | Q13442814 |
| P50 | author | Zhen Yang | Q38304491 |
| James K. Chen | Q39883191 | ||
| P2093 | author name string | Shuo Lin | |
| Song Li | |||
| Jin Jiang | |||
| Yun Zhao | |||
| Jing Xiang | |||
| Hongbo Yang | |||
| Nengdong Wang | |||
| Joel Hyman | |||
| P2860 | cites work | A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro | Q24315704 |
| Activating Smoothened mutations in sporadic basal-cell carcinoma | Q24318403 | ||
| Small molecule modulation of Smoothened activity | Q24540343 | ||
| Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells | Q24544004 | ||
| Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened | Q24682703 | ||
| Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists | Q24794838 | ||
| Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine | Q28138510 | ||
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| The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas | Q28288407 | ||
| Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 | Q28299947 | ||
| Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord | Q28566360 | ||
| Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog | Q28586621 | ||
| Sonic hedgehog regulates branching morphogenesis in the mammalian lung | Q28590700 | ||
| Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened | Q28646558 | ||
| The patched signaling pathway in tumorigenesis and development: lessons from animal models | Q33727365 | ||
| Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. | Q33965304 | ||
| The developmental biology of brain tumors. | Q34205396 | ||
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| A small-molecule antagonist of the hedgehog signaling pathway. | Q40077689 | ||
| Hedgehog signaling in the murine melanoma microenvironment | Q40086681 | ||
| In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice. | Q40470521 | ||
| Hedgehog signalling in prostate regeneration, neoplasia and metastasis | Q40516539 | ||
| Deconstructing the hedgehog pathway in development and disease | Q41844372 | ||
| Critical time window of hedgehog-dependent angiogenesis in murine yolk sac. | Q42170635 | ||
| Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development | Q42486654 | ||
| Medulloblastoma growth inhibition by hedgehog pathway blockade | Q44119270 | ||
| Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells | Q44576153 | ||
| Patching the gaps in Hedgehog signalling | Q45345885 | ||
| A concise and diversity-oriented approach to the synthesis of SAG derivatives | Q47377246 | ||
| A molecular fingerprint for medulloblastoma. | Q47616912 | ||
| Teratogen-mediated inhibition of target tissue response to Shh signaling | Q48004971 | ||
| Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. | Q52087418 | ||
| The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors | Q73954844 | ||
| P433 | issue | 31 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 20876-20884 | |
| P577 | publication date | 2009-04-14 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Converse conformational control of smoothened activity by structurally related small molecules | |
| P478 | volume | 284 |
| Q28485870 | A novel PEGylated liposome-encapsulated SANT75 suppresses tumor growth through inhibiting hedgehog signaling pathway |
| Q38920722 | Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway |
| Q33877283 | Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways |
| Q26865136 | Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy |
| Q37306391 | Drugging the Cancer Stem Cell Compartment: Lessons Learned from the Hedgehog and Wnt Signal Transduction Pathways |
| Q50467477 | Fish in chips: an automated microfluidic device to study drug dynamics in vivo using zebrafish embryos. |
| Q39175185 | Hedgehog Signaling: From Basic Biology to Cancer Therapy |
| Q39367534 | Hedgehog inhibitor decreases chemosensitivity to 5-fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer |
| Q38072095 | Hedgehog pathway inhibitors: a patent review (2009--present). |
| Q37890489 | Hedgehog signaling pathway as a therapeutic target in various types of cancer |
| Q38831323 | Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish |
| Q27316947 | In vivo imaging of Hedgehog pathway activation with a nuclear fluorescent reporter |
| Q37809668 | International Union of Basic and Clinical Pharmacology. LXXX. The Class Frizzled Receptors |
| Q48210660 | Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors. |
| Q36187353 | Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis |
| Q33540741 | Small-molecule inhibitors of the hedgehog signaling pathway as cancer therapeutics |
| Q91530365 | Smoothened stimulation by membrane sterols drives Hedgehog pathway activity |
| Q28478568 | Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened |
| Q36058644 | Sonic hedgehog is indirectly required for intraretinal axon pathfinding by regulating chemokine expression in the optic stalk |
| Q99418925 | Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling |
| Q47218042 | Strategies to target the Hedgehog signaling pathway for cancer therapy. |
| Q27684635 | Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs |
| Q36073607 | Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors |
| Q51622187 | The Loss of a Sugar Chain at C(3) Position Enhances Stemucronatoside K-Induced Apoptosis, Cell Cycle Arrest, and Hedgehog Pathway Inhibition in HT-29 Cells. |
| Q38051564 | Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile |
| Q33784918 | Visualization of Gli activity in craniofacial tissues of hedgehog-pathway reporter transgenic zebrafish |
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