Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers

scientific article

Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2009PLoSO...4.5474W
P356DOI10.1371/JOURNAL.PONE.0005474
P932PMC publication ID2677159
P698PubMed publication ID19434236
P5875ResearchGate publication ID24419703

P50authorNesrina ImamiQ41630663
P2093author name stringMark R Nelson
Brian Gazzard
Samantha J Westrop
Jeffrey Pido-Lopez
Frances M Gotch
Nadeem A Qazi
P2860cites workMicrobial translocation is a cause of systemic immune activation in chronic HIV infectionQ22251054
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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsQ29616205
The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infectionQ33904114
Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy.Q34009945
The differential ability of HLA B*5701+ long-term nonprogressors and progressors to restrict human immunodeficiency virus replication is not caused by loss of recognition of autologous viral gag sequencesQ34200151
A balanced type 1/type 2 response is associated with long-term nonprogressive human immunodeficiency virus type 1 infectionQ34344555
Effector and memory CTL differentiationQ34584974
Changes in paracrine interleukin-2 requirement, CCR7 expression, frequency, and cytokine secretion of human immunodeficiency virus-specific CD4+ T cells are a consequence of antigen loadQ35784804
Host factors influencing susceptibility to HIV infection and AIDS progressionQ35995936
T cell homeostasis: thymus regeneration and peripheral T cell restoration in mice with a reduced fraction of competent precursorsQ36376275
Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.Q36925272
Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapyQ36950611
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune controlQ37054526
Macrophage-dependent response of immune human T lymphocytes to PPD in vitro. Influence of HLA-D histocompatibilityQ39451372
Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 diseaseQ43582240
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infectionQ44902494
Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapyQ45721932
Even individuals considered as long-term nonprogressors show biological signs of progression after 10 years of human immunodeficiency virus infectionQ45761406
Thymic function in severely immunodeficient HIV type 1-infected patients receiving stable and effective antiretroviral therapyQ46944589
HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation.Q51995804
Highly active anti-retroviral therapy (HAART)-induced maintenance of adaptive but not innate immune parameters is associated with protection from HIV-induced mortality.Q53608089
Rev activity determines sensitivity of HIV-1-infected primary T cells to CTL killing.Q53940326
Preserved immune system in long-term asymptomatic vertically HIV-1 infected childrenQ57080067
CD8+ T-cell responses to different HIV proteins have discordant associations with viral loadQ57259602
Changes in thymic function with age and during the treatment of HIV infectionQ59066353
Disease progression in macaques with low SIV replication levels: on the relevance of TREC countsQ61565796
Rapid qualitative and quantitative analysis of T-cell responses in HIV-1-infected individuals receiving successful HAART and HIV-1 sero-negative controls: Concomitant assessment of perforin, IFN-γ and IL-4 secretionQ61767282
Initiation of Antiretroviral Therapy During Recent HIV-1 Infection Results in Lower Residual Viral ReservoirsQ61767288
Thymic Output during Initial Highly Active Antiretroviral Therapy (HAART) and during HAART Supplementation with Interleukin 2 and/or with HIV Type 1 Immunogen (Remune)Q61767312
Immune responses and reconstitution in HIV-1 infected individuals: impact of anti-retroviral therapy, cytokines and therapeutic vaccinationQ61767322
Immunopathogenesis of HIV infectionQ71752121
A simple method for the measurement of sjTREC levels in bloodQ73409321
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressorsQ78342521
Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infectionQ78551235
Thymic output and HIV infection: on the right TRECQ81119966
Elite suppression of HIV-1 replicationQ83051579
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)e5474
P577publication date2009-05-12
P1433published inPLOS OneQ564954
P1476titleTransient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers
P478volume4

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cites work (P2860)
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