Identification and characterization of inhibitors of West Nile virus

scientific article

Identification and characterization of inhibitors of West Nile virus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ANTIVIRAL.2009.03.005
P932PMC publication ID3214651
P698PubMed publication ID19501258
P5875ResearchGate publication ID26271295

P50authorPei-Yong ShiQ59435668
Bo ZhangQ64160150
Hongping DongQ114420607
Gang ZouQ40130449
P2093author name stringFrancesc Puig-Basagoiti
Min Qing
Zhiming Yuan
P2860cites workInhibition of dengue virus serotypes 1 to 4 in vero cell cultures with morpholino oligomersQ24520621
Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivoQ24531947
Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infectionQ24562957
Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structureQ40363892
Use of RNA interference to prevent lethal murine west nile virus infectionQ40513711
Treatment of West Nile virus-infected mice with reactive immunoglobulin reduces fetal titers and increases dam survivalQ40514962
Prophylactic and therapeutic efficacy of human intravenous immunoglobulin in treating West Nile virus infection in miceQ40556192
Protection of mice against Japanese encephalitis virus by passive administration with monoclonal antibodiesQ40781926
Protection against 17D yellow fever encephalitis in mice by passive transfer of monoclonal antibodies to the nonstructural glycoprotein gp48 and by active immunization with gp48.Q40814867
The carboxy-terminal part of the NS 3 protein of the West Nile Flavivirus can be isolated as a soluble protein after proteolytic cleavage and represents an RNA-stimulated NTPaseQ42985863
The flavivirus-conserved penta-nucleotide in the 3' stem-loop of the West Nile virus genome requires a specific sequence and structure for RNA synthesis, but not for viral translationQ42989770
Inhibitory effect of RNAi on Japanese encephalitis virus replication in vitro and in vivoQ42997248
Elucidation of the topography and determination of the protective epitopes on the E glycoprotein of Saint Louis encephalitis virus by passive transfer with monoclonal antibodiesQ43030485
West Nile virus.Q51714865
Flavivirus genome organization, expression, and replicationQ24575500
Inhibition of interferon signaling by dengue virusQ24630622
In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virusQ24678543
A single siRNA suppresses fatal encephalitis induced by two different flavivirusesQ25255046
Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replicationQ27469445
Alpha-glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulumQ27469618
Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of FlavivirusesQ27469841
Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonistQ27472136
An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterizationQ27472613
High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discoveryQ27472764
Antiviral effects of an iminosugar derivative on flavivirus infectionsQ27472863
Mutations in the Yellow Fever Virus Nonstructural Protein NS2A Selectively Block Production of Infectious ParticlesQ27472873
Infectious cDNA clone of the epidemic west nile virus from New York CityQ27472878
Triaryl pyrazoline compound inhibits flavivirus RNA replicationQ27473130
West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5Q27477465
Molecular and Functional Analyses of Kunjin Virus Infectious cDNA Clones Demonstrate the Essential Roles for NS2A in Virus Assembly and for a Nonconservative Residue in NS3 in RNA ReplicationQ27477562
Structure and Function of Flavivirus NS5 MethyltransferaseQ27478377
Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation EventsQ27480347
A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesisQ27481037
Identification of Novel Small-Molecule Inhibitors of West Nile Virus InfectionQ27484983
Functional Analysis of Mosquito-Borne Flavivirus Conserved Sequence Elements within 3' Untranslated Region of West Nile Virus by Use of a Reporting Replicon That Differentiates between Viral Translation and RNA ReplicationQ27485398
Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNAQ27486408
Potential High-Throughput Assay for Screening Inhibitors of West Nile Virus ReplicationQ27487569
Efficacy of Interferon -2b and Ribavirin Against West Nile Virus In VitroQ27489383
Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activityQ28276481
Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteinsQ29620712
Discovery of small molecule inhibitors of West Nile virus using a high-throughput sub-genomic replicon screenQ33244670
A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitorQ33555761
West Nile virus inhibits the signal transduction pathway of alpha interferonQ33718537
Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirusQ36771001
Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cellsQ40079953
Antibody prophylaxis and therapy against West Nile virus infection in wild-type and immunodeficient miceQ40344535
P433issue1
P921main subjectWest Nile virusQ158856
P304page(s)71-79
P577publication date2009-04-01
P1433published inAntiviral ResearchQ4775352
P1476titleIdentification and characterization of inhibitors of West Nile virus
P478volume83

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cites work (P2860)
Q95839233An RNA-dependent RNA polymerase inhibitor for tick-borne encephalitis virus
Q36585005Design, synthesis and characterization of novel 1,2-benzisothiazol-3(2H)-one and 1,3,4-oxadiazole hybrid derivatives: potent inhibitors of Dengue and West Nile virus NS2B/NS3 proteases
Q35212106Flavivirus RNA cap methyltransferase: structure, function, and inhibition
Q33584783Generation of West Nile virus infectious clones containing amino acid insertions between capsid and capsid anchor
Q39626614Generation of a recombinant West Nile virus stably expressing the Gaussia luciferase for neutralization assay
Q26700125Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase
Q40506281Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana).
Q22583530Identification of a novel antiviral inhibitor of the flavivirus guanylyltransferase enzyme
Q39081733Identification of a small-molecule inhibitor of dengue virus using a replicon system
Q42978698In vitro and in vivo activity of AS101 against West Nile virus (WNV).
Q41903737Inactivation of the tick-borne encephalitis virus by RNA-cleaving compounds
Q91950266Lentivirus expressing shRNAs inhibit the replication of contagious ecthyma virus by targeting DNA polymerase gene
Q28548514Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase
Q56795718Nucleic Acid-Based Infectious and Pseudo-Infectious Flavivirus Vaccines
Q40185164Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase
Q33519132Regioselective intramolecular dipolar cycloaddition of azides and unsymmetrical alkynes
Q35018619S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase
Q33852451Small molecule drug discovery for Dengue and West Nile viruses: applying experience from hepatitis C virus

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