Enprostil. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease

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Enprostil. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease is …
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scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1005810378
P356DOI10.2165/00003495-198734050-00003
P698PubMed publication ID3121276

P2093author name stringGoa KL
Monk JP
P2860cites workGastric antisecretory and antiulcer properties of enprostil, (+/-)-11 alpha, 15 alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-9-oxoprosta- 4,5,13(t)-trienoic acid methyl esterQ28290166
Enprostil and ranitidine in prevention of duodenal ulcer relapse: one year double blind comparative trial.Q34069536
Misoprostol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer diseaseQ39540382
Comparative clinical trial of enprostil and ranitidine in the treatment of gastric ulcerQ39542302
Enprostil and ranitidine in duodenal ulcer healing: double blind comparative trial.Q39544363
Omeprazole. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peptic ulcer disease and Zollinger-Ellison syndromeQ39741061
Effect of enprostil, a synthetic prostaglandin E2 on 24 hour intragastric acidity, nocturnal acid and pepsin secretionQ41891763
Effects of enprostil on platelets, endothelial cells, and other cell types, and second messenger systems by which these effects are mediatedQ41950512
Prostaglandins and cellular restitution in the gastric mucosaQ42525595
Effect of a single oral dose of enprostil on gastric secretion and gastrin release. Studies in healthy volunteers and patients with pernicious anemiaQ43490492
Enprostil, a synthetic prostaglandin E2 analogue, inhibits meal-stimulated gastric acid secretion and gastrin release in patients with duodenal ulcer.Q51632993
Protective effects of the synthetic prostaglandin enprostil on the gastric microvasculature after ethanol injury in the rat.Q52490373
Gastroduodenal mucosal secretion of bicarbonate and mucus. Physiologic control and stimulation by prostaglandins.Q54423969
Protective effects of the prostaglandins on the gastric mucosaQ68736632
Prostanoid inhibition of canine parietal cellsQ68973035
Protection against aspirin-induced antral and duodenal damage with enprostil. A double-blind endoscopic studyQ69936489
Antisecretory and serum gastrin lowering effect of enprostil in patients with duodenal ulcer diseaseQ69954547
Platelet function in patients receiving enprostilQ70011792
Twenty-four-hour intragastric acidity and clinical trial of bedtime enprostil 70 micrograms compared with ranitidine 300 mg in duodenal ulcerQ70074577
Enprostil, in contrast to cimetidine, does not inhibit propranolol metabolismQ70292706
[Enprostil in the acute treatment of duodenal ulcer: direct comparative study with pirenzepin]Q70296835
Stimulatory effect of enprostil, an anti-ulcer prostaglandin, on gastric mucus secretionQ70304517
Reduction by enprostil of aspirin-induced blood loss from human gastric mucosaQ70304523
Protective effect of enprostil against aspirin-induced gastroduodenal mucosal injury in man. Comparison with cimetidine and sucralfateQ70304527
Treatment of duodenal ulcer with enprostil, a synthetic prostaglandin E2 analogueQ70304531
Treatment of duodenal ulcer with enprostil, a prostaglandin E2 analogueQ70304533
Comparison of enprostil and cimetidine in active duodenal ulcer disease. Summary of pooled European studiesQ70304536
Treatment of gastric ulcer with enprostilQ70304539
Gastric mucosal binding studies with enprostil: a potent anti-ulcer prostaglandinQ70317694
Stimulation of HCO3- secretion by the prostaglandin E2 analog enprostil: studies in human stomach and rat duodenumQ70333779
Enprostil and cimetidine: comparative efficacy and safety in patients with duodenal ulcerQ70343016
Influence of cigarette smoking on healing and relapse in duodenal ulcer diseaseQ72559716
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpeptic ulcer diseaseQ172941
pharmacokineticsQ323936
pharmacodynamicsQ725307
P304page(s)539-559
P577publication date1987-11-01
P1433published inDrugsQ3040094
P1476titleEnprostil. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease
P478volume34