Pathogenesis and treatment of the antiphospholipid antibody syndrome

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Pathogenesis and treatment of the antiphospholipid antibody syndrome is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0025-7125(05)70509-5
P698PubMed publication ID9012759

P50authorMichelle A. PetriQ67485110
P2860cites workLupus anticoagulant and heparin-associated bleedingQ71933468
Normal fetal growth in women with antiphospholipid syndrome treated with high-dose intravenous immunoglobulin (IVIG)Q72022440
Down-regulation of maternal antiphospholipid antibodies during early pregnancy and pregnancy outcomeQ72059538
Acquired free protein S deficiency is associated with antiphospholipid antibodies and increased thrombin generation in patients with systemic lupus erythematosusQ72140744
Crossreaction between antibodies to oxidised low-density lipoprotein and to cardiolipin in systemic lupus erythematosusQ72214273
A prospective study on pregnancy risk of antiphospholipid antibodies in association with systemic lupus erythematosusQ72284377
Low-dose aspirin for prevention of pregnancy losses in women with primary antiphospholipid syndromeQ72347443
Inhibition of prostacyclin release by endothelial binding anticardiolipin antibodies in thrombosis-prone patients with systemic lupus erythematosus and the antiphospholipid syndromeQ72373656
Arterial thrombosis, intrauterine death and "lupus" antiocoagulant: detection of immunoglobulin interfering with prostacyclin formationQ72451284
Intravenous immunoglobulin therapy for the antiphospholipid syndrome in pregnancyQ72547160
The management of thrombosis in the antiphospholipid-antibody syndromeQ72619159
Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patientsQ72671950
Unexplained thrombosis and factor V Leiden mutationQ72688139
Transesophageal echocardiographic detection of multiple mitral valve masses in primary antiphospholipid syndrome with strokeQ72746735
Combined corticosteroid and aspirin treatment for the high risk lupus pregnancyQ72838416
Anti-idiotypes against antiphospholipid antibodies are present in normal polyspecific immunoglobulins for therapeutic useQ72857704
Hypercoagulable statesQ72939029
Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H)Q24558202
Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosusQ28261335
Prothrombinase activity of human platelets is inhibited by beta 2-glycoprotein-IQ28304443
Beta 2-glycoprotein-I (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregationQ28305356
Double heart valve replacement disclosing antiphospholipid syndromeQ33354607
Induction of experimental anti-phospholipid syndrome associated with SLE following immunization with human monoclonal pathogenic anti-DNA idiotypeQ33355283
Anticardiolipin antibodies in heparin-associated thrombocytopeniaQ33356781
Induction of primary antiphospholipid syndrome in mice by immunization with a human monoclonal anticardiolipin antibody (H-3)Q33364820
Antiphospholipid Thrombosis: Clinical Course after the First Thrombotic Event in 70 PatientsQ33369688
In vivo efficacy of intravenous gammaglobulins in patients with lupus anticoagulant is not mediated by an anti-idiotypic mechanismQ33373724
Cerebral ischemic events associated with endocarditis, retinal vascular disease, and lupus anticoagulantQ33381987
Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodiesQ33388194
Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Prevalence and clinical significanceQ33392960
Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patientsQ33438663
Myocardial infarction in a young man with systemic lupus erythematosus, deep vein thrombosis, and antibodies to phospholipidQ33446337
Coagulation screen is more specific than the anticardiolipin antibody ELISA in defining a thrombotic subset of lupus patientsQ33447381
Thrombosis, recurrent fetal loss, and thrombocytopenia. Predictive value of the anticardiolipin antibody testQ33453407
Antibody to cardiolipin as a predictor of fetal distress or death in pregnant patients with systemic lupus erythematosusQ33458388
Thrombocytopenia in SLE and related autoimmune disorders: association with anticardiolipin antibodyQ33459225
Thrombosis in patients with the lupus anticoagulantQ33486691
A family study of anticardiolipin antibodies and associated clinical conditionsQ33487561
Lupus anticoagulant, heparin use, and thrombocytopenia in patients with chronic thromboembolic pulmonary hypertension: a preliminary reportQ33488491
Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparinQ33489438
Role of IL-3 in the antiphospholipid syndromeQ33490039
Pregnancy outcome in women with antiphospholipid antibodiesQ33493247
The effect of aspirin on recurrent fetal loss in experimental antiphospholipid syndromeQ33493954
The effect of intravenous gamma-globulin on the induction of experimental antiphospholipid syndromeQ33494140
Prevention of fetal loss in experimental antiphospholipid syndrome by in vivo administration of recombinant interleukin-3Q33494657
Avascular necrosis of bone in systemic lupus erythematosus: possible role of haemostatic abnormalitiesQ33561944
Prospective study of fluctuations of lupus anticoagulant activity and anticardiolipin antibody titre in patients with systemic lupus erythematosusQ33564380
Patients with antiphospholipid antibodies and venous thrombosis should receive long term anticoagulant treatmentQ33565796
Antiphospholipid antibodies (aPL) in systemic lupus erythematosus. Are they specific tools for the diagnosis of aPL syndrome?Q33566129
Antithrombotic effects of thrombin-induced activation of endogenous protein C in primatesQ33905952
Mutation in blood coagulation factor V associated with resistance to activated protein C.Q34340007
Use of antithrombotic agents during pregnancyQ35373440
Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein IQ35822631
(NZW x BXSB)F1 hybrid. A model of acute lupus and coronary vascular disease with myocardial infarctionQ36345299
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytesQ36363024
Effect of prednisone and hydroxychloroquine on coronary artery disease risk factors in systemic lupus erythematosus: a longitudinal data analysisQ36747001
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosusQ37722431
Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptives with differing progestagen componentsQ38508071
The frequency of lupus anticoagulant in systemic lupus erythematosus. A study of sixty consecutive patients by activated partial thromboplastin time, Russell viper venom time, and anticardiolipin antibody levelQ39289964
Hydroxychloroquine and postoperative thromboembolism after total hip replacementQ39531655
Cerebrovascular ischemia associated with lupus anticoagulantQ39593049
Lupus anticoagulant and pregnancyQ39849377
Cognitive deficit associated with rheumatic diseases: neuropsychological perspectivesQ40422622
Antiphospholipid antibodies and eicosanoidsQ40558516
Thoughts on the mechanism of pregnancy loss associated with the antiphospholipid syndromeQ40558522
Assays for detection of antiphospholipid antibodiesQ40558527
Cerebrovascular disease and antiphospholipid antibodies in systemic lupus erythematosus, lupus-like disease, and the primary antiphospholipid syndromeQ41238775
Obstetric performance in patients with the lupus anticoagulant and/or anticardiolipin antibodiesQ41837702
Risk factors for complications of chronic anticoagulation. A multicenter study. Warfarin Optimized Outpatient Follow-up Study GroupQ42287205
Detection of endothelial cell-reactive immunoglobulin in patients with anti-phospholipid antibodiesQ43719415
Effectiveness of prednisolone/aspirin therapy for recurrent aborters with antiphospholipid antibodyQ43960513
Successful treatment in two women with antiphospholipid antibodies and refractory pregnancy losses with intravenous immunoglobulin infusionsQ44067471
Anticardiolipin antibodies and lupus anticoagulants comprise separate antibody subgroups with different phospholipid binding characteristics.Q45239170
Deep Vein Thrombosis: Prevalence of Etiologic Factors and Results of Management in 100 Consecutive PatientsQ46010793
Valvular heart disease in the primary antiphospholipid syndromeQ46730841
Prevention of fetal loss in experimental antiphospholipid syndrome by low-molecular-weight heparinQ47389805
Cardioembolic caudate infarction as a cause of hemichorea in lupus anticoagulant syndromeQ48295399
Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosisQ48394757
Congenic autoimmune murine models of central nervous system disease in connective tissue disordersQ48766365
Corticosteroids and neuropsychological functioning in patients with systemic lupus erythematosus.Q51131677
Resistance to activated protein C as a basis for venous thrombosis.Q54214042
Lupus anticoagulant and the fibrinolytic system in young patients with strokeQ58421453
Antiphospholipid Antibodies and Endothelial CellsQ62395221
Serum apolipoprotein H levels in systemic lupus erythematosus are not influenced by antiphospholipid antibodiesQ67482133
The thrombotic diathesis associated with the presence of phospholipid antibodies may be due to low levels of free protein SQ67545591
Prevention of anticardiolipin antibody-related pregnancy losses with prednisone and aspirinQ67566965
A prospective, controlled multicenter study on the obstetric risks of pregnant women with antiphospholipid antibodiesQ67586423
Antiendothelial Cell Antibodies in Patients with the Antiphospholipid SyndromeQ67886354
Association of anti-beta 2 glycoprotein I antibodies with lupus-type circulating anticoagulant and thrombosis in systemic lupus erythematosusQ68008000
Anticardiolipin cofactor(s) and differential diagnosis of autoimmune diseaseQ68091809
Antiphospholipid antibodies and atherosclerosisQ68116700
Myocardial infarction caused by cardiac microvasculopathy in a patient with the primary antiphospholipid syndromeQ68125663
Repeated fetal losses associated with antiphospholipid antibodies: a collaborative randomized trial comparing prednisone with low-dose heparin treatmentQ68139494
Preliminary classification criteria for the antiphospholipid syndrome within systemic lupus erythematosusQ68153286
A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physiciansQ68227750
In vitro activation of the contact activation system (Hageman factor system) in plasma by acidic phospholipids and the inhibitory effect of I on this activationQ68310414
Increased thromboxane formation in patients with antiphospholipid syndromeQ68379902
Spontaneous recurrent fetal wastage and autoimmune abnormalities: a study of fourteen casesQ68796709
Skin lesions associated with circulating lupus anticoagulantQ69193395
Neurological disease associated with antiphospholipid antibodiesQ69624901
Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapyQ69742234
Antibodies to cardiolipin in young survivors of myocardial infarction: an association with recurrent cardiovascular eventsQ69874910
Prednisone does not prevent recurrent fetal death in women with antiphospholipid antibodyQ69946465
Hyperhomocysteinemia: an independent risk factor for vascular diseaseQ70131136
Chorea in systemic lupus erythematosus and "lupus-like" disease: association with antiphospholipid antibodiesQ70346602
An unusual syndrome of a devastating noninflammatory vasculopathy associated with anticardiolipin antibodies: report of two casesQ70365615
The relationship between lupus anticoagulants and antibodies to phospholipidQ70370974
Prevention of Postoperative Deep Venous Thrombosis and Pulmonary EmbolismQ70549361
Umbilical artery and ductal blood flow velocities in patients treated with aspirin and prednisone for presence of anticardiolipin antibodyQ70712836
In vitro lupus anticoagulant neutralizing activity of intravenous immunoglobulinQ70762184
Systemic lupus erythematosus and habitual abortion. Case reportQ71351766
Decidual vasculopathy and extensive placental infarction in a patient with repeated thromboembolic accidents, recurrent fetal loss, and a lupus anticoagulantQ71593361
Interaction of heparin with antiphospholipid antibodies (APA) from the sera of women with recurrent pregnancy loss (RPL)Q71908100
P433issue1
P304page(s)151-177
P577publication date1997-01-01
P1433published inMedical Clinics of North AmericaQ15761972
P1476titlePathogenesis and treatment of the antiphospholipid antibody syndrome
P478volume81

Reverse relations

cites work (P2860)
Q35574348A Cutaneous Manifestation of Antiphospholipid Antibody Syndrome
Q44057192Abnormal regional cerebral blood flow in primary antiphospholipid antibody syndrome patients with normal magnetic resonance imaging findings. A preliminary report
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Q36256231Anticardiolipin antibodies and ocular disease
Q79245648Anticardiolipin antibodies in various diseases in Taiwan: a retrospective analysis
Q74616049Antiphospholipid antibodies are a risk factor for early renal allograft failure: isolation of antiphospholipid antibodies from a thrombosed renal allograft
Q35104711Antiphospholipid antibodies: discovery, definitions, detection and disease
Q41713369Antiphospholipid antibody syndrome: current concepts
Q35984353Aortoiliac thrombosis in antiphospholipid syndrome-case report and literature review
Q52008946Behavioral and cognitive deficits occur only after prolonged exposure of mice to antiphospholipid antibodies.
Q33332894Cerebral blood flow and glucose metabolism in multi-infarct-dementia related to primary antiphospholipid antibody syndrome
Q77769404Evidence that anticardiolipin antibodies are independent risk factors for atherosclerotic vascular disease
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Q35549772How to treat women with antiphospholipid antibodies in pregnancy?
Q33338363Hyperactivity in a mouse model of the antiphospholipid syndrome
Q58647328IgA Anticardiolipin in Patients with Gastroenteric Tumor
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Q34250901Neuropsychiatric lupus
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Q33722879Women's health

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