Interactions between herbal medicines and prescribed drugs: an updated systematic review

scientific article

Interactions between herbal medicines and prescribed drugs: an updated systematic review is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P6179Dimensions Publication ID1005228311
P356DOI10.2165/11317010-000000000-00000
P698PubMed publication ID19719333
P5875ResearchGate publication ID26779082

P50authorEdzard ErnstQ70166
Angelo A. IzzoQ42411084
P2860cites workSt John's wort for major depressionQ24241294
Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazideQ24651117
Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokineticsQ24656624
Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjectsQ24678775
Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and femalesQ24679237
Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in renal transplant recipients.Q24815942
Herb-drug interactions: a literature reviewQ28176037
Multiple doses of saw palmetto (Serenoa repens) did not alter cytochrome P450 2D6 and 3A4 activity in normal volunteersQ28190298
Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interactionQ28213939
The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivoQ28241382
Herb-drug interactions in oncology: focus on mechanisms of inductionQ28255139
Coma in a patient with Alzheimer's disease taking low dose trazodone and gingko bilobaQ28344326
Herb-drug interactions: review and assessment of report reliabilityQ28365912
Herbal medicines as a factor in deliriumQ28369070
Interactions between herbal medicines and prescribed drugs: a systematic reviewQ30790065
Effects of St. John's wort on irinotecan metabolismQ33184162
Herbal and dietary supplement--drug interactions in patients with chronic illnesses.Q33317576
Clinical evidence of herb-drug interactions: a systematic review by the natural standard research collaboration.Q33392243
Kava and dopamine antagonismQ33734168
St John's wort: Prozac from the plant kingdom.Q33950220
The effect of garlic supplements on the pharmacokinetics of saquinavirQ33956369
Herbal medicines and perioperative careQ34083672
Multiple-Dose Administration of Ginkgo biloba Did Not Affect Cytochrome P-450 2D6 or 3A4 Activity in Normal VolunteersQ34277542
Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidenceQ34309286
In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypesQ34419646
Interaction between cyclosporine and Hypericum perforatum (St. John's wort) after organ transplantationQ34421963
Adverse effects profile of the herbal antidepressant St. John's wort (Hypericum perforatum L.).Q34484334
Garlic interaction with fluindione: a case report.Q44696317
Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteersQ44697441
Effect of St. John's wort on the pharmacokinetics of theophylline in healthy volunteersQ44697443
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazoleQ44787217
St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolismQ44827285
The influence of St John's Wort on CYP2C19 activity with respect to genotypeQ44897883
Effect of St John's wort dose and preparations on the pharmacokinetics of digoxinQ44923001
Brief communication: American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled TrialQ44967299
Induction of imatinib metabolism by hypericum perforatumQ45007465
Impact of cytochrome P-450 inhibition by cimetidine and induction by carbamazepine on the kinetics of hypericin and pseudohypericin in healthy volunteersQ45062240
Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction.Q45095090
In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto.Q45146006
The influence of St. John's wort on the pharmacokinetics and protein binding of imatinib mesylateQ45146720
Studies on interactions between functional foods or dietary supplements and medicines. IV. Effects of ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in healthy volunteersQ45171973
Pharmacogenetics and herb-drug interactions: experience with Ginkgo biloba and omeprazoleQ45193955
Serotonin syndrome resulting from an herbal detox cocktailQ45235359
CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populationsQ45259361
Efficacy and tolerability of Hypericum perforatum in major depressive disorder in comparison with selective serotonin reuptake inhibitors: a meta-analysisQ46231784
St John's wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptiveQ46240940
Effect of Ginkgo biloba (EGb 761) and aspirin on platelet aggregation and platelet function analysis among older adults at risk of cardiovascular disease: a randomized clinical trialQ46371414
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extractQ46459610
Interaction between warfarin and Panax ginseng in ischemic stroke patientsQ46475692
Interaction of St. John's Wort with oral contraceptives: effects on the pharmacokinetics of norethindrone and ethinyl estradiol, ovarian activity and breakthrough bleedingQ46507921
St. John's Wort, corticosteroids, cocaine, alcohol ... and a first manic episodeQ46587528
Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokineticsQ46589222
Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. John's wort). Case of drug interaction?Q46657916
Influence of garlic (Allium sativum) on the pharmacokinetics of docetaxelQ46774278
The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose.Q46845808
Fatal seizures due to potential herb-drug interactions with Ginkgo bilobaQ46898710
Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivoQ46905661
Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrateQ46908034
Lack of pharmacokinetic interaction between St. John's wort and prednisoneQ46958985
Association between priapism and concurrent use of risperidone and Ginkgo bilobaQ46972442
Traditional remedies and food supplements. A 5-year toxicological study (1991-1995).Q47775763
Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivoQ48598672
Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteersQ48651682
Low cyclosporin-A level due to Saint-John's-wort in heart transplant patientsQ48686546
St. John's wort and antidepressant drug interactions in the elderlyQ48749332
Delayed emergence and St. John's wort.Q49137471
Gingko biloba: a case report of herbal medicine and bleeding postoperatively from a laparoscopic cholecystectomy.Q50184418
Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trialQ50237753
Herbal medicines and postoperative haemorrhage.Q51221712
A possible cause of cardiovascular collapse during anesthesia: long-term use of St. John's Wort.Q51365200
Interaction between a commercially available St. John's wort product (Movina) and atorvastatin in patients with hypercholesterolemia.Q51465582
Hazardous pharmacokinetic interaction of Saint John's wort (Hypericum perforatum) with the immunosuppressant cyclosporin.Q52968365
Mania in a patient receiving testosterone replacement postorchidectomy taking St John's wort and sertraline.Q53781790
Impact of ginkgo biloba on the pharmacokinetics of digoxin.Q53859229
Indinavir concentrations and St John's wort.Q55033637
Interaction between curry ingredient (karela) and drug (chlorpropamide)Q66702306
Bees, ginseng and MAOIs revisitedQ68002127
Interaction of ginseng with phenelzineQ69061821
Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzymeQ37161542
Potential of pharmacokinetic profiling for detecting herbal interactions with drugsQ37163340
In vivo assessment of herb-drug interactions: possible utility of a pharmacogenetic approach?Q37212905
A critical evaluation of drug interactions with Echinacea spp.Q37212909
Clinical drugs that interact with St. John's wort and implication in drug developmentQ37232852
Serenoa repens (saw palmetto): a systematic review of adverse eventsQ37547218
Back to basics.Q40477719
Pharmacodynamic interaction studies of Ginkgo biloba with cilostazol and clopidogrel in healthy human subjectsQ41123941
Herbal medicines: can we do without pharmacologist?Q42003490
Drug interaction between St John's Wort and quazepam.Q42158860
Coma from the health food store: interaction between kava and alprazolamQ42551855
Effects of Hypericum perforatum on ivabradine pharmacokinetics in healthy volunteers: an open-label, pharmacokinetic interaction clinical trialQ42598774
Effect of St John's wort on imatinib mesylate pharmacokineticsQ42637650
Unwanted pregnancy on self-medication with St John's wort despite hormonal contraceptionQ42760300
Prolonged oro-facial dystonia in a 58 year old female following therapy with bupropion and St John's WortQ42958186
Drug interaction between St John's wort and nevirapineQ43556089
St. John's wort: effect on CYP2D6 activity using dextromethorphan-dextrorphan ratiosQ43761157
The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activityQ43775254
Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatinQ43830741
Ginko, Vioxx and excessive bleeding--possible drug-herb interactions: case reportQ43858589
Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's wort ( Hypericum perforatum ).Q43859427
Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wortQ43940399
Hypomania induced by herbal and pharmaceutical psychotropic medicines following mild traumatic brain injuryQ43959255
Effect of St John's wort on the pharmacokinetics of fexofenadineQ44043537
Phenelzine and the dream machine--ramblings and reflections.Q44073363
Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humansQ44139044
Possible serotonin syndrome after combination of buspirone and St John's WortQ44263574
Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjectsQ44289523
Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patientsQ44362349
Methadone maintenance treatment and St. John's Wort - a case reportQ44370716
Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofenQ44485571
Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteersQ44532788
Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzymeQ44586531
The interaction between St John's wort and an oral contraceptiveQ44685310
Hyperforin in St. John's wort drug interactionsQ34494412
St John's Wort supplements endanger the success of organ transplantationQ34558766
Complementary medicines in psychiatry: review of effectiveness and safetyQ34564616
Serotonin syndrome and rhabdomyolysis induced by concomitant use of triptans, fluoxetine and hypericumQ34583010
Garlic (Allium sativum L.): adverse effects and drug interactions in humansQ34698908
Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs: what is the evidence?Q34739887
No clinically relevant CYP3A induction after St. John's wort with low hyperforin content in healthy volunteers.Q34819036
St. John's wort and oral contraceptives: reasons for concern?Q35026875
Panax ginseng.Q35574823
Drug interactions between herbal and prescription medicines.Q35593896
Interaction of St John's wort with conventional drugs: systematic review of clinical trialsQ35615173
Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo bilobaQ35765836
Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humansQ35781981
Interaction of St John's wort with low‐dose oral contraceptive therapy: a randomized controlled trialQ35825530
Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjectsQ35826093
Effect of short-term administration of garlic supplements on single-dose ritonavir pharmacokinetics in healthy volunteersQ35846696
Drug interactions with St John's wort : mechanisms and clinical implicationsQ35879020
Adverse effects of St. John's Wort: a systematic reviewQ35956630
Herb-drug interactions: an overview of the clinical evidenceQ36014951
Clinical risk management of herb-drug interactionsQ36025053
Interactions between herbal and conventional medicinesQ36082038
Possible drug-metabolism interactions of medicinal herbs with antiretroviral agentsQ36551135
Development of quantitative structure-activity relationships and its application in rational drug designQ36683643
The recovery time-course of CYP3A after induction by St John's wort administrationQ36729151
Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey.Q36779045
Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical CenterQ36840598
Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjectsQ36842490
A detailed safety assessment of a saw palmetto extractQ36843661
Identification of drugs that interact with herbs in drug development.Q36913494
Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.Q36926307
Patient Disclosure about Herb and Supplement Use among Adults in the US.Q36981134
Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoringQ37016989
The effect of herbal medicines on platelet function: an in vivo experiment and review of the literatureQ37036593
Effect of Ginkgo biloba extract on microsomal enzyme inductionQ69651450
The effect of garlic extract on human metabolism of acetaminophenQ72104641
Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)Q73145709
Probable interaction between warfarin and ginsengQ73166583
Spontaneous hyphema associated with ingestion of Ginkgo biloba extractQ73199998
Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitor nevirapine by human hepatic cytochromes P-450Q73201582
Drug interaction of herbal tea containing St. John's wort with cyclosporineQ73218902
Interaction of Hypericum perforatum (St. John's wort) with cyclosporin A metabolism in a patient after liver transplantationQ73246112
St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4Q73443725
Lack of effect of St John's Wort on carbamazepine pharmacokinetics in healthy volunteersQ73443729
Acute heart transplant rejection due to Saint John's wortQ73465831
Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteersQ73501072
Profound drop of cyclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum)Q73893153
Drug interaction of St John's wort with cyclosporinQ73923310
[St. Johns wort-venlafaxine interaction]Q74100379
Unexplained decrease of cyclosporin trough levels in a compliant renal transplant patientQ74291281
Drug interaction between St. John's wort and cyclosporineQ74299422
SSRIs and St.John's Wort: possible toxicity?Q74368781
[St. John's wort: interaction with cyclosporine increases risk of rejection for the kidney transplant and raises daily cost of medication]Q74521003
Association of Ginkgo biloba with intracerebral hemorrhageQ74673650
St John's wort: a hidden risk for transplant patientsQ77708483
Potential metabolic interaction between St. John's wort and theophyllineQ77761677
Hypericum perforatum (St John's wort) in depression: pest or blessing?Q77793078
Herbal medicine: the dangers of drug interactionQ78365884
Potential drug-herb interaction with antiplatelet/anticoagulant drugsQ79214582
Induction of intestinal P-glycoprotein by St John's wort reduces the oral bioavailability of talinololQ80058660
Brief report: enzyme inducers reduce elimination half-life after a single dose of nevirapine in healthy womenQ80186135
Herb-drug interactions. St. John's wort and prescription medicationsQ80387628
Herb-drug interactionsQ81133365
Aged garlic extract may be safe for patients on warfarin therapyQ82582261
Safety of St John's wort (Hypericum perforatum)Q93929858
Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjectsQ94681842
Inhibition of P-glycoprotein in Caco-2 cells: effects of herbal remedies frequently used by cancer patientsQ94702263
P433issue13
P921main subjectsystematic reviewQ1504425
P304page(s)1777-1798
P577publication date2009-01-01
P1433published inDrugsQ3040094
P1476titleInteractions between herbal medicines and prescribed drugs: an updated systematic review
P478volume69

Reverse relations

cites work (P2860)
Q36460605A Blended Learning Course Design in Clinical Pharmacology for Post-graduate Dental Students
Q89861542A Systematic Review of the Effect of Dietary Supplements on Cognitive Performance in Healthy Young Adults and Military Personnel
Q35565585A pilot study of website information regarding aromatase inhibitors: dietary supplement interactions
Q38366431A review of nurses' knowledge, attitudes, and ability to communicate the risks and benefits of complementary and alternative medicine
Q21090750A review of potential harmful interactions between anticoagulant/antiplatelet agents and Chinese herbal medicines
Q37422735A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors.
Q38209332A systematic review and meta-analysis of herbal medicine on chronic obstructive pulmonary diseases
Q38630265A systematic review of the pharmacokinetic and pharmacodynamic interactions of herbal medicine with warfarin.
Q47145098Abuse and Misuse of Selected Dietary Supplements Among Adolescents: a Look at Poison Center Data
Q48215007Acute and chronic pretreatment with essential oil of peppermint (Mentha × piperita L., Lamiaceae) influences drug effects.
Q37593205Addition of propolis to irinotecan therapy prolongs survival in ehrlich ascites tumor-bearing mice.
Q38749357Adulterated and Counterfeit Male Enhancement Nutraceuticals and Dietary Supplements Pose a Real Threat to the Management of Erectile Dysfunction: A Global Perspective.
Q50094359Adulteration and Counterfeiting of Online Nutraceutical Formulations in the United States: Time for Intervention?
Q26800279Adverse drug reactions and drug-drug interactions with over-the-counter NSAIDs
Q38611443Adverse food-drug interactions
Q31051777Allergy-Like Immediate Reactions with Herbal Medicines: A Retrospective Study Using Data from VigiBase®.
Q37013930Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors.
Q44590864Alternative therapies for asthma: are patients at risk?
Q39444589An automated system for retrieving herb-drug interaction related articles from MEDLINE.
Q28477174An epidemiological study of concomitant use of Chinese medicine and antipsychotics in schizophrenic patients: implication for herb-drug interaction
Q35919968An overview of the evidence and mechanisms of herb-drug interactions.
Q33947228Antibacterial activity of some selected medicinal plants of Pakistan
Q85005859Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities
Q64900241Association between complementary and alternative medicine use and prolonged time to conventional treatment among Thai cancer patients in a tertiary-care hospital.
Q37710055Behaviors of consumers, physicians and pharmacists in response to adverse events associated with dietary supplement use
Q49376486Biological activities of the red algae Galaxaura rugosa and Liagora hawaiiana butters
Q46369656Biotransformation enzyme activities and phase I metabolites analysis in Litopenaeus vannamei following intramuscular administration of T-2 toxin
Q33986613Buyer beware? Does the information provided with herbal products available over the counter enable safe use?
Q42126731Cardioprotective Effects of Atorvastatin plus Trimetazidine in Percutaneous Coronary Intervention.
Q35685299Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla
Q38616585Classification of Use Status for Dietary Supplements in Clinical Notes
Q38221696Clinical applications of herbal medicines for anxiety and insomnia; targeting patients with bipolar disorder
Q36417984Clinical pharmacology in sleep medicine
Q37968621Clinically significant drug interactions with newer antidepressants
Q50243040Coltsfoot as a potential cause of deep vein thrombosis and pulmonary embolism in a patient also consuming kava and blue vervain
Q38011807Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux.
Q35849421Common dietary supplements for cognitive health
Q35671034Common use of dietary supplements for bipolar disorder: a naturalistic, self-reported study
Q38875174Complementary and alternative medicine therapies for chronic pain
Q38202901Complementary and alternative medicine: risks and special considerations in pretransplant and posttransplant patients
Q45749220Complementary or alternative medicine in cancer care-myths and realities
Q35586021Concomitant use of dietary supplements and medicines in patients due to miscommunication with physicians in Japan
Q37585353Concurrent Use of Conventional Drugs with Chinese Herbal Products in Taiwan: A Population-based Study
Q47202565Concurrent Use of Prescription Drugs and Herbal Medicinal Products in Older Adults: A Systematic Review.
Q43604171Concurrent use of drugs and supplements in a community-dwelling population aged 50 years or more: potential benefits and risks.
Q37640084Cytochrome P450 and P-Glycoprotein-Mediated Interactions Involving African Herbs Indicated for Common Noncommunicable Diseases.
Q35725540Cytochrome P450 enzyme mediated herbal drug interactions (Part 1)
Q35729029Cytochrome P450 enzyme mediated herbal drug interactions (Part 2)
Q37802740Deleterious Effects of Reactive Metabolites
Q92373474Dietary and Supplement-Based Complementary and Alternative Medicine Use in Pediatric Autism Spectrum Disorder
Q36054864Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.
Q36068525Do your patients with bipolar disorder use dietary supplements?
Q46025254Doctor-patient communication and cancer patients' choice of alternative therapies as supplement or alternative to conventional care.
Q83274402Drug interactions with herbal medicines
Q57180639Drug-drug interactions and clinical considerations with co-administration of antiretrovirals and psychotropic drugs
Q35904433Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers.
Q37314453Effect of Red Ginseng on cytochrome P450 and P-glycoprotein activities in healthy volunteers
Q34339576Effect of garlic on serum lipids: an updated meta-analysis
Q53671478Effect of kanglaite on rat cytochrome P450.
Q42074732Effect of milk thistle on the pharmacokinetics of darunavir-ritonavir in HIV-infected patients.
Q54511648Effectiveness and safety of combination treatment of herbal medicines and oral antihistamines for atopic dermatitis: a retrospective chart review.
Q58615950Effects of Common CYP1A2 Genotypes and other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: an Exploratory Analysis
Q34362562Effects of Flos carthami on CYP2D6 and on the Pharmacokinetics of Metoprolol in Rats
Q47748496Effects of capsicine on rat cytochrome P450 isoforms CYP1A2, CYP2C19, and CYP3A4.
Q43712337Effects of natural products on the function of human organic anion transporting polypeptide 1B1.
Q47782012Effects of vitexin on the pharmacokinetics and mRNA expression of CYP isozymes in rats
Q37107406Efficacy of Hypericum extract WS(®) 5570 compared with paroxetine in patients with a moderate major depressive episode - a subgroup analysis
Q99240445Emerging Complementary and Integrative Therapies for Geriatric Mental Health
Q52677334Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone.
Q35113280Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies
Q35141015Ethnobotanical and antimicrobial study of some selected medicinal plants used in Khyber Pakhtunkhwa (KPK) as a potential source to cure infectious diseases
Q34306204Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature review
Q34238039Evaluation of metabolism-mediated herb-drug interactions
Q88012905Flupirtine drug-induced liver injury in a patient developing acute liver failure
Q38695934Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review
Q42864265Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans
Q36679039Ginkgo biloba Extract for Patients with Early Diabetic Nephropathy: A Systematic Review
Q38109094Ginkgo biloba extracts: a review of the pharmacokinetics of the active ingredients
Q34483552Herb-drug interaction between Echinacea purpurea and darunavir-ritonavir in HIV-infected patients
Q36276879Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients
Q34279245Herb-drug interactions: an overview of systematic reviews
Q58576453Herbal Bioenhancers in Veterinary Phytomedicine
Q64235486Herbal Medicinal Product Use During Pregnancy and the Postnatal Period: A Systematic Review
Q92132099Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
Q33786771Herbal and Alternative Medicine Use in Tanzanian Adults Admitted with Hypertension-Related Diseases: A Mixed-Methods Study
Q84030111Herbal medicines and forensic investigations
Q57273966Herbal tea extracts inhibit Cytochrome P450 3A4 in vitro
Q36916959Hypericum perforatum-induced hepatotoxicity with possible association with copaiba (Copaifera langsdorffii Desf):case report
Q34360600Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions
Q43051294Important drug-nutrient interactions
Q41534845In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities
Q34774934Inappropriate usage of dietary supplements in patients by miscommunication with physicians in Japan
Q36469701Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants
Q64230731Influences of on the Activities of CYP450 Enzymes in Rats with a Cocktail Approach
Q35557149Infrequent older adult-primary care provider discussion and documentation of dietary supplements
Q35162440Inhibition of major drug metabolizing CYPs by common herbal medicines used by HIV/AIDS patients in Africa-- implications for herb-drug interactions
Q49804065Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells.
Q86056783Inhibitory action of Epilobium hirsutum extract and its constituent ellagic acid on drug-metabolizing enzymes
Q35187885Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities.
Q42953779Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity
Q34512871Interactions between Natural Health Products and Oral Anticoagulants: Spontaneous Reports in the Italian Surveillance System of Natural Health Products
Q38283110Interactions between herbs and antidiabetics: an overview of the mechanisms, evidence, importance, and management
Q34124444Interactions between herbs and conventional drugs: overview of the clinical data.
Q38581233Issues and promise in clinical studies of botanicals with anticonvulsant potential
Q37133257Knowledge, attitude, and practices toward ayurvedic medicine use among allopathic resident doctors: A cross-sectional study at a tertiary care hospital in India
Q50052519Local Radiotherapy Affects Drug Pharmacokinetics-Exploration of a Neglected but Significant Uncertainty of Cancer Therapy
Q38201108Manic psychosis associated with ginseng: a report of two cases and discussion of the literature
Q37637048Medication use by middle-aged and older participants of an exercise study: results from the Brain in Motion study.
Q35059110Microbiological profiling and the demonstration of in vitro anti-bacterial traits of the major oral herbal medicines used in Dhaka Metropolis
Q47219850Mining Adverse Events of Dietary Supplements from Product Labels by Topic Modeling
Q26781613Modelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectives
Q36744650Natural health product-drug interaction tool: A scoping review.
Q33946426Natural products and supplements for geriatric depression and cognitive disorders: an evaluation of the research
Q38074992Nuclear receptors in herb-drug interactions.
Q37304704Optimizing chemotherapy: concomitant medication lists
Q33709156Patient needs and preferences for herb-drug-disease interaction alerts: a structured interview study
Q38074712Pharmacogenetics of clinical response to risperidone.
Q85829560Pharmacokinetic comparisons of benzoylmesaconine in rats using ultra-performance liquid chromatography-tandem mass spectrometry after administration of pure benzoylmesaconine and Wutou decoction
Q50094239Pharmacology and pharmacokinetics of imatinib in pediatric patients
Q86502171Pinelliae rhizoma, a toxic chinese herb, can significantly inhibit CYP3A activity in rats
Q37179352Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1
Q39624983Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa
Q88956486Potential Influence of Centrally Acting Herbal Drugs on Transporters at the Blood-Cerebrospinal Fluid Barrier and Blood-Brain Barrier
Q37803219Potential of St John's Wort for the treatment of depression: the economic perspective.
Q34700821Potential of garlic (Allium sativum) in lowering high blood pressure: mechanisms of action and clinical relevance
Q38040597Potential of treating age-related depression and cognitive decline with nutraceutical approaches: a mini-review.
Q47137566Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey
Q64938443Pregnant women's use and attitude toward herbal, vitamin, and mineral supplements in an academic tertiary care center, Riyadh, Saudi Arabia.
Q55072787Principles of pharmacological research of nutraceuticals.
Q34071450Provider and patient expectations for dietary supplement discussions
Q38047816Psychotropic drug-drug interactions involving P-glycoprotein
Q24628778Rainforest pharmacopeia in Madagascar provides high value for current local and prospective global uses
Q64100479Regulation of P-glycoprotein by Bajijiasu in vitro and in vivo by activating the Nrf2-mediated signalling pathway
Q88657353Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
Q38213152Review article: Herbal hepatotoxicity--an update on traditional Chinese medicine preparations
Q85823665Role of clinical pharmacists to prevent drug interactions in cancer outpatients: a single-centre experience
Q41167590Safety Analysis of Panax Ginseng in Randomized Clinical Trials: A Systematic Review
Q35490308Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity
Q88709362Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
Q28539251Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein
Q89944830Suboptimal Health, Dietary Supplementation, and Public Health Approaches to Regulatory Challenges in Dubai
Q55301721The Complementary Health Approaches for Pain Survey (CHAPS): Validity testing and characteristics of a rural population with pain.
Q38110713The classification and application of toxic Chinese materia medica.
Q37982110The effect of garlic supplements and phytochemicals on the ADMET properties of drugs
Q54473907The interaction potential of herbal medicinal products: a luminescence-based screening platform assessing effects on cytochrome P450 and its use with devil's claw (Harpagophyti radix) preparations.
Q36324428The prevalence, characteristics, and factors associated with purchasing Chinese herbal medicine among adults in Taiwan
Q35810068The roles of carboxylesterase and CYP isozymes on the in vitro metabolism of T-2 toxin
Q38068221Theranostics meets traditional Chinese medicine: rational prediction of drug-herb interactions
Q33630966Therapeutic Effects of Phytochemicals and Medicinal Herbs on Depression.
Q37943827Therapeutic potential of ginseng in the management of cardiovascular disorders
Q34614106Thiazide-like diuretic drug metolazone activates human pregnane X receptor to induce cytochrome 3A4 and multidrug-resistance protein 1.
Q92240828Traditional Medicine and Its Role in the Management of Diabetes Mellitus: "Patients' and Herbalists' Perspectives"
Q54960358Traditional medicines and alternative practice in the management of prostate diseases in southern Ghana
Q30395449Traditional use of medicinal plants in the boreal forest of Canada: review and perspectives
Q59400990Traditional, complementary and alternative medicine use in Sub-Saharan Africa: a systematic review
Q37387226Trans-Resveratrol Enhances the Anticoagulant Activity of Warfarin in a Mouse Model
Q37280785Trends in the use of oral contraceptives among adolescents and young women in Spain
Q91626717U.S. Filipino Adults' Patterns of CAM Use and Medical Pluralism: Secondary Analysis of 2012 National Health Interview Survey
Q36719646UGT concentrations in human rectal tissue after multidose, oral curcumin
Q38293810Understanding interactions between Chinese medicines and pharmaceutical drugs in integrative healthcare
Q90599845Understanding the relevance of herb-drug interaction studies with special focus on interplays: a prerequisite for integrative medicine
Q37562491Unproven Therapies for Diabetes and Their Implications
Q33648514Use of Complementary and Alternative Medicine (CAM) in cancer patients: An Italian multicenter survey.
Q35095883Use of bodily sensations as a risk assessment tool: exploring people with Multiple Sclerosis' views on risks of negative interactions between herbal medicine and conventional drug therapies
Q53666242Use of dietary supplements for cognitive health: results of a national survey of adults in the United States.
Q33882005Use of herbal medicinal products among children and adolescents in Germany
Q40614867Use of over-the-counter (OTC) drugs and perceptions of OTC drug safety among German adults
Q30420889Vietnamese traditional medicine from a pharmacist's perspective
Q37907479What do I tell patients about saw palmetto for benign prostatic hyperplasia?
Q37037596What do most erectile dysfunction guidelines have in common? No evidence-based discussion or recommendation of heart-healthy lifestyle changes and/or Panax ginseng
Q64053346What has been the impact of the Traditional Herbal Registration (THR) scheme in the UK on information provided with herbal products bought over the counter?

Search more.